DigiferruginolCAS# 24094-45-9 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
Cas No. | 24094-45-9 | SDF | Download SDF |
PubChem ID | 32209 | Appearance | Powder |
Formula | C15H10O4 | M.Wt | 254.2 |
Type of Compound | Anthraquinones | Storage | Desiccate at -20°C |
Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
Chemical Name | 1-hydroxy-2-(hydroxymethyl)anthracene-9,10-dione | ||
SMILES | C1=CC=C2C(=C1)C(=O)C3=C(C2=O)C(=C(C=C3)CO)O | ||
Standard InChIKey | JCZCSQSSSAHDCB-UHFFFAOYSA-N | ||
Standard InChI | InChI=1S/C15H10O4/c16-7-8-5-6-11-12(13(8)17)15(19)10-4-2-1-3-9(10)14(11)18/h1-6,16-17H,7H2 | ||
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
||
About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
||
Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. |
Description | 1. Digiferruginol has cytotoxic activity. 2. Digiferruginol and hederagenin show weak effect on porcine respiratory and reproductive syndrome virus (PRRSV) with an IC50 value of 80.5 ± 16.9 uM(SI = 19.9) and 43.2 ± 7.4 uM (SI = 13.1), respectively. |
Targets | Antifection |
Digiferruginol Dilution Calculator
Digiferruginol Molarity Calculator
1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
1 mM | 3.9339 mL | 19.6696 mL | 39.3391 mL | 78.6782 mL | 98.3478 mL |
5 mM | 0.7868 mL | 3.9339 mL | 7.8678 mL | 15.7356 mL | 19.6696 mL |
10 mM | 0.3934 mL | 1.967 mL | 3.9339 mL | 7.8678 mL | 9.8348 mL |
50 mM | 0.0787 mL | 0.3934 mL | 0.7868 mL | 1.5736 mL | 1.967 mL |
100 mM | 0.0393 mL | 0.1967 mL | 0.3934 mL | 0.7868 mL | 0.9835 mL |
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. |
Calcutta University
University of Minnesota
University of Maryland School of Medicine
University of Illinois at Chicago
The Ohio State University
University of Zurich
Harvard University
Colorado State University
Auburn University
Yale University
Worcester Polytechnic Institute
Washington State University
Stanford University
University of Leipzig
Universidade da Beira Interior
The Institute of Cancer Research
Heidelberg University
University of Amsterdam
University of Auckland
TsingHua University
The University of Michigan
Miami University
DRURY University
Jilin University
Fudan University
Wuhan University
Sun Yat-sen University
Universite de Paris
Deemed University
Auckland University
The University of Tokyo
Korea University
- 5-Chlorothiophene-2-carboxylic acid
Catalog No.:BCC8745
CAS No.:24065-33-6
- Isocurcumenol
Catalog No.:BCN3526
CAS No.:24063-71-6
- Salvicine
Catalog No.:BCN3163
CAS No.:240423-23-8
- H-Glu-pNA
Catalog No.:BCC2923
CAS No.:24032-35-7
- Agathadiol diacetate
Catalog No.:BCN5093
CAS No.:24022-13-7
- 2-Amino-3-benzyloxypyridine
Catalog No.:BCC8524
CAS No.:24016-03-3
- Griffithinam
Catalog No.:BCN4744
CAS No.:240122-32-1
- Griffithazanone A
Catalog No.:BCN4813
CAS No.:240122-30-9
- QX 314 bromide
Catalog No.:BCC6889
CAS No.:24003-58-5
- Pyrocatechol monoglucoside
Catalog No.:BCN4667
CAS No.:2400-71-7
- Dehydroepiandrosterone enanthate
Catalog No.:BCC8930
CAS No.:23983-43-9
- 13-Deacetyltaxachitriene A
Catalog No.:BCN7390
CAS No.:239800-99-8
- 6-Isopentenyloxyisobergapten
Catalog No.:BCC8110
CAS No.:24099-29-4
- Sibiricose A6
Catalog No.:BCN2786
CAS No.:241125-75-7
- Sibiricaxanthone B
Catalog No.:BCN2784
CAS No.:241125-81-5
- Adaphostin
Catalog No.:BCC3890
CAS No.:241127-58-2
- Flupenthixol dihydrochloride
Catalog No.:BCC7851
CAS No.:2413-38-9
- 2-CMDO
Catalog No.:BCC5671
CAS No.:24140-98-5
- Khellactone
Catalog No.:BCN6684
CAS No.:24144-61-4
- TMS
Catalog No.:BCC7093
CAS No.:24144-92-1
- Isavuconazole
Catalog No.:BCC5515
CAS No.:241479-67-4
- Catalpol
Catalog No.:BCN5094
CAS No.:2415-24-9
- N-(4-Methylphenyl)-3-oxobutanamide
Catalog No.:BCC9058
CAS No.:2415-85-2
- Febrifugine
Catalog No.:BCN3269
CAS No.:24159-07-7
Antitumor agents, 75. Synthesis of cytotoxic anthraquinones digiferruginol and morindaparvin-B.[Pubmed:3841556]
J Nat Prod. 1985 Nov-Dec;48(6):948-51.
A simple and efficient synthesis of Digiferruginol (4) and morindaparvin-B (10) is described. Marschalk reaction of 1-hydroxyanthraquinone afforded 1-hydroxy-2-methylanthraquinone (2). Treatment of 2 with N-bromosuccinimide and benzoyl peroxide led to 1-hydroxy-2-bromomethylanthraquinone (3), which was converted to 4 with AgNO3 in quantitative yield. Methylation of 1,5-dihydroxyanthraquinone yielded a dimethyl ether (6), which was partially demethylated with boron trifluoride to a difluoroboron chelate (7). Treatment of 7 with alkaline HCHO and sodium dithionate gave rise to 1-hydroxy-2-hydroxy-methyl-5-methoxyanthraquinone (9). Cleavage of the 5-methyl ether of 9 with boron tribromide furnished 10.