DiscodermideCAS# 134458-00-7 |
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| Cas No. | 134458-00-7 | SDF | Download SDF |
| PubChem ID | 54720479 | Appearance | Powder |
| Formula | C27H34N2O6 | M.Wt | 482.58 |
| Type of Compound | Alkaloids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | (1Z,3E,19E)-2,25-dihydroxy-10-methyl-12-oxa-22,27-diazahexacyclo[24.2.1.05,17.08,16.09,14.011,13]nonacosa-1,3,19-triene-21,28,29-trione | ||
| SMILES | CC1C2C3CCC4C=CC(=C5C(=O)C(C(CCNC(=O)C=CCC4C3CC2C6C1O6)O)NC5=O)O | ||
| Standard InChIKey | FMGYABSXIBFKHP-HJOPEIERSA-N | ||
| Standard InChI | InChI=1S/C27H34N2O6/c1-12-21-15-7-5-13-6-8-18(30)22-24(33)23(29-27(22)34)19(31)9-10-28-20(32)4-2-3-14(13)16(15)11-17(21)26-25(12)35-26/h2,4,6,8,12-17,19,21,23,25-26,30-31H,3,5,7,9-11H2,1H3,(H,28,32)(H,29,34)/b4-2+,8-6+,22-18- | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
The Discodermia dissoluta
| Description | 1. Discodermide has antifungal and cytotoxic activities. |
| Targets | Antifection |
Discodermide Dilution Calculator
Discodermide Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.0722 mL | 10.361 mL | 20.722 mL | 41.4439 mL | 51.8049 mL |
| 5 mM | 0.4144 mL | 2.0722 mL | 4.1444 mL | 8.2888 mL | 10.361 mL |
| 10 mM | 0.2072 mL | 1.0361 mL | 2.0722 mL | 4.1444 mL | 5.1805 mL |
| 50 mM | 0.0414 mL | 0.2072 mL | 0.4144 mL | 0.8289 mL | 1.0361 mL |
| 100 mM | 0.0207 mL | 0.1036 mL | 0.2072 mL | 0.4144 mL | 0.518 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Discodermide: A new bioactive macrocyclic lactam from the marine sponge Discodermia dissoluta
J. Org. Chem., 1991, 56(16):4833-40
A new macrocyclic lactam, Discodermide (1), was isolated from a Caribbean marine sponge, Discodermia dissoluta. Its structure was elucidated through a combination of spectroscopic techniques, in particular NMR spectroscopy. The carbon skeleton displayed by Discodermide is new; Discodermide is antifungal and cytotoxic.
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