1-Cinnamoyl-3-hydroxypyrrolidineCAS# 1344876-77-2 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
| Cas No. | 1344876-77-2 | SDF | Download SDF |
| PubChem ID | 62917426 | Appearance | Powder |
| Formula | C13H15NO2 | M.Wt | 217.3 |
| Type of Compound | Alkaloids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | (E)-1-(3-hydroxypyrrolidin-1-yl)-3-phenylprop-2-en-1-one | ||
| SMILES | C1CN(CC1O)C(=O)C=CC2=CC=CC=C2 | ||
| Standard InChIKey | FHARWVZPAKTDJR-VOTSOKGWSA-N | ||
| Standard InChI | InChI=1S/C13H15NO2/c15-12-8-9-14(10-12)13(16)7-6-11-4-2-1-3-5-11/h1-7,12,15H,8-10H2/b7-6+ | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | 1-Cinnamoyl-3-hydroxypyrrolidine is a natural product from Piper nigrum. |
| Structure Identification | Planta Med. 2017 Jan;83(1-02):143-50.Antifungal Amide Alkaloids from the Aerial Parts of Piper flaviflorum and Piper sarmentosum.[Pubmed: 27405106]
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1-Cinnamoyl-3-hydroxypyrrolidine Dilution Calculator
1-Cinnamoyl-3-hydroxypyrrolidine Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 4.6019 mL | 23.0097 mL | 46.0193 mL | 92.0387 mL | 115.0483 mL |
| 5 mM | 0.9204 mL | 4.6019 mL | 9.2039 mL | 18.4077 mL | 23.0097 mL |
| 10 mM | 0.4602 mL | 2.301 mL | 4.6019 mL | 9.2039 mL | 11.5048 mL |
| 50 mM | 0.092 mL | 0.4602 mL | 0.9204 mL | 1.8408 mL | 2.301 mL |
| 100 mM | 0.046 mL | 0.2301 mL | 0.4602 mL | 0.9204 mL | 1.1505 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Antifungal Amide Alkaloids from the Aerial Parts of Piper flaviflorum and Piper sarmentosum.[Pubmed:27405106]
Planta Med. 2017 Jan;83(1-02):143-150.
Sixty-three amide alkaloids, including three new, piperflaviflorine A (1), piperflaviflorine B (2), and sarmentamide D (4), and two previously synthesized ones, (1E,3S)-1-cinnamoyl-3- hydroxypyrrolidine (3) and N-[7'-(4'-methoxyphenyl)ethyl]-2-methoxybenzamide (5), were isolated from the aerial parts of Piper flaviflorum and Piper sarmentosum. Their structures were elucidated by detailed spectroscopic analysis and, in case of 3, by single-crystal X-ray diffraction. Most of the isolates were tested for their antifungal and antibacterial activities. Ten amides (6-15) showed antifungal activity against Cryptococcus neoformans ATCC 90 113 with IC50 values in the range between 4.7 and 20.0 microg/mL.
