Doxapram hydrochloride monohydrateCAS# 7081-53-0 |
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| Cas No. | 7081-53-0 | SDF | Download SDF |
| PubChem ID | 64648 | Appearance | Powder |
| Formula | C24H33ClN2O3 | M.Wt | 433.0 |
| Type of Compound | N/A | Storage | Desiccate at -20°C |
| Solubility | DMSO : ≥ 55 mg/mL (127.03 mM) *"≥" means soluble, but saturation unknown. | ||
| Chemical Name | 1-ethyl-4-(2-morpholin-4-ylethyl)-3,3-diphenylpyrrolidin-2-one;hydrate;hydrochloride | ||
| SMILES | CCN1CC(C(C1=O)(C2=CC=CC=C2)C3=CC=CC=C3)CCN4CCOCC4.O.Cl | ||
| Standard InChIKey | ZOMBFZRWMLIDPX-UHFFFAOYSA-N | ||
| Standard InChI | InChI=1S/C24H30N2O2.ClH.H2O/c1-2-26-19-22(13-14-25-15-17-28-18-16-25)24(23(26)27,20-9-5-3-6-10-20)21-11-7-4-8-12-21;;/h3-12,22H,2,13-19H2,1H3;1H;1H2 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
Doxapram hydrochloride monohydrate Dilution Calculator
Doxapram hydrochloride monohydrate Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.3095 mL | 11.5473 mL | 23.0947 mL | 46.1894 mL | 57.7367 mL |
| 5 mM | 0.4619 mL | 2.3095 mL | 4.6189 mL | 9.2379 mL | 11.5473 mL |
| 10 mM | 0.2309 mL | 1.1547 mL | 2.3095 mL | 4.6189 mL | 5.7737 mL |
| 50 mM | 0.0462 mL | 0.2309 mL | 0.4619 mL | 0.9238 mL | 1.1547 mL |
| 100 mM | 0.0231 mL | 0.1155 mL | 0.2309 mL | 0.4619 mL | 0.5774 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Doxapram hydrochloride hydrate inhibits TASK-1, TASK-3, TASK-1/TASK-3 heterodimeric channel function with EC50 of 410 nM, 37 μM, 9 μM, respectively.
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