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7,3',4'-Tri-O-methyleriodictyol

CAS# 70987-96-1

7,3',4'-Tri-O-methyleriodictyol

2D Structure

Catalog No. BCN7766----Order now to get a substantial discount!

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7,3',4'-Tri-O-methyleriodictyol: 5mg $725 In Stock
7,3',4'-Tri-O-methyleriodictyol: 10mg Please Inquire In Stock
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7,3',4'-Tri-O-methyleriodictyol: 200mg Please Inquire Please Inquire
7,3',4'-Tri-O-methyleriodictyol: 500mg Please Inquire Please Inquire
7,3',4'-Tri-O-methyleriodictyol: 1000mg Please Inquire Please Inquire

Quality Control of 7,3',4'-Tri-O-methyleriodictyol

3D structure

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7,3',4'-Tri-O-methyleriodictyol

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Chemical Properties of 7,3',4'-Tri-O-methyleriodictyol

Cas No. 70987-96-1 SDF Download SDF
PubChem ID 14078482 Appearance Powder
Formula C18H18O6 M.Wt 330.33
Type of Compound Flavonoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (2S)-2-(3,4-dimethoxyphenyl)-5-hydroxy-7-methoxy-2,3-dihydrochromen-4-one
SMILES COC1=C(C=C(C=C1)C2CC(=O)C3=C(C=C(C=C3O2)OC)O)OC
Standard InChIKey MRFOCZPULZWYTJ-HNNXBMFYSA-N
Standard InChI InChI=1S/C18H18O6/c1-21-11-7-12(19)18-13(20)9-15(24-17(18)8-11)10-4-5-14(22-2)16(6-10)23-3/h4-8,15,19H,9H2,1-3H3/t15-/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of 7,3',4'-Tri-O-methyleriodictyol

The whole plants of Pogostemon cablin.

Biological Activity of 7,3',4'-Tri-O-methyleriodictyol

Description1. 7, 3',4'-Tri-O-methyleriodictyol has antimutagenic activity.

7,3',4'-Tri-O-methyleriodictyol Dilution Calculator

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7,3',4'-Tri-O-methyleriodictyol Molarity Calculator

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Preparing Stock Solutions of 7,3',4'-Tri-O-methyleriodictyol

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.0273 mL 15.1364 mL 30.2728 mL 60.5455 mL 75.6819 mL
5 mM 0.6055 mL 3.0273 mL 6.0546 mL 12.1091 mL 15.1364 mL
10 mM 0.3027 mL 1.5136 mL 3.0273 mL 6.0546 mL 7.5682 mL
50 mM 0.0605 mL 0.3027 mL 0.6055 mL 1.2109 mL 1.5136 mL
100 mM 0.0303 mL 0.1514 mL 0.3027 mL 0.6055 mL 0.7568 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on 7,3',4'-Tri-O-methyleriodictyol

Antimutagenic activity of flavonoids from Pogostemon cablin.[Pubmed:10725128]

J Agric Food Chem. 2000 Mar;48(3):642-7.

A methanol extract from Pogostemon cablin showed a suppressive effect on umu gene expression of SOS response in Salmonella typhimurium TA1535/pSK1002 against the mutagen 2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide (furylfuramide). The methanol extract was re-extracted with hexane, dichloromethane, butanol, and water. A dichloromethane fraction showed a suppressive effect. Suppressive compounds against furylfuramide in the dichloromethane fraction were isolated by SiO(2) column chromatography and identified as 7,4'-di-O-methyleriodictyol (1), 7, 3',4'-tri-O-methyleriodictyol (2), and 3,7,4'-tri-O-methylkaempferol (3). In addition, three flavonoids, ombuine (4), pachypodol (5), and kumatakenin (6), were isolated and identified from the dichrolomethane fraction. Compounds 1 and 3 suppressed >50% of the SOS-inducing activity at <0.6 micromol/mL, and the ID(50) values of both compounds were 0.25 micromol/mL. Compound 2 showed a weakly suppressive effect (17%) at a concentration of 0.6 micromol/mL, and compounds 4-6 did not. These compounds were also assayed with 3-amino-1,4-dimethyl-5H-pyrido[4,3-b]indole (Trp-P-1), which requires liver metabolizing enzymes. Compounds 3-6 suppressed >80% of the SOS-inducing activity of Trp-P-1 at <0.06 micromol/mL, and compounds 1 and 2 suppressed 87 and 63% at a concentration of 0.3 micromol/mL. In addition, these compounds were assayed with activated Trp-P-1, and the suppressed effects of these compounds were further decreased when compared to Trp-P-1. The antimutagenic activities of these compounds against furylfuramide, Trp-P-1, and activated Trp-P-1 were assayed by the Ames test using S. typhimurium TA100.

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