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Ganoderic acid Epsilon

CAS# 294674-05-8

Ganoderic acid Epsilon

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Quality Control of Ganoderic acid Epsilon

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Chemical structure

Ganoderic acid Epsilon

3D structure

Chemical Properties of Ganoderic acid Epsilon

Cas No. 294674-05-8 SDF Download SDF
PubChem ID 15427810.0 Appearance Powder
Formula C30H44O7 M.Wt 516.67
Type of Compound N/A Storage Desiccate at -20°C
Synonyms Ganoderic acid ε
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (E,4S,6R)-6-[(3S,5R,7S,10S,13R,14R,17R)-3,7-dihydroxy-4,4,10,13,14-pentamethyl-11,15-dioxo-2,3,5,6,7,12,16,17-octahydro-1H-cyclopenta[a]phenanthren-17-yl]-4-hydroxy-2-methylhept-2-enoic acid
SMILES CC(CC(C=C(C)C(=O)O)O)C1CC(=O)C2(C1(CC(=O)C3=C2C(CC4C3(CCC(C4(C)C)O)C)O)C)C
Standard InChIKey MIWGXXQCEDNROQ-UZOYOLKESA-N
Standard InChI InChI=1S/C30H44O7/c1-15(10-17(31)11-16(2)26(36)37)18-12-23(35)30(7)25-19(32)13-21-27(3,4)22(34)8-9-28(21,5)24(25)20(33)14-29(18,30)6/h11,15,17-19,21-22,31-32,34H,8-10,12-14H2,1-7H3,(H,36,37)/b16-11+/t15-,17+,18-,19+,21+,22+,28+,29-,30+/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Ganoderic acid Epsilon

Ganoderma Lucidum Karst

Ganoderic acid Epsilon Dilution Calculator

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Ganoderic acid Epsilon Molarity Calculator

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Preparing Stock Solutions of Ganoderic acid Epsilon

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.9355 mL 9.6774 mL 19.3547 mL 38.7094 mL 48.3868 mL
5 mM 0.3871 mL 1.9355 mL 3.8709 mL 7.7419 mL 9.6774 mL
10 mM 0.1935 mL 0.9677 mL 1.9355 mL 3.8709 mL 4.8387 mL
50 mM 0.0387 mL 0.1935 mL 0.3871 mL 0.7742 mL 0.9677 mL
100 mM 0.0194 mL 0.0968 mL 0.1935 mL 0.3871 mL 0.4839 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Ganoderic acid Epsilon

A new triterpene from the fruiting bodies of Ganoderma lucidum.[Pubmed:19806918]

Yao Xue Xue Bao. 2009 Jul;44(7):768-70.

A new lanostanoid triterpene, named ganoderitriol M (1), together with a known triterpene Ganoderic acid Epsilon (2), were isolated from the fruiting bodies of G lucidum. Compound 1 was deduced as (24S)-lanosta-7-oxo-8-en-3beta, 24, 25-triol on the basis of spectral analysis (UV, IR, MS, 1H NMR, 13C NMR and 2D NMR).

A new lanostane-type triterpene from the fruiting bodies of Ganoderma lucidum.[Pubmed:12067158]

J Asian Nat Prod Res. 2002 Jun;4(2):129-34.

A new lanostane-type triterpene, named ganoderic acid LM2 (5), was isolated from the fruiting bodies of Ganoderma lucidum. Its structure was characterized as (23S) 7beta, -dihydroxy-3, 11, 15-trioxo-5alpha-lanosta-8, 24-dien-26-oic acid by 1D- and 2D-NMR spectra. In addition, a known triterpene, Ganoderic acid Epsilon (4), was obtained. Both of them exhibited potent enhancement of ConA-induced mice splenocytes proliferation in vitro.

Triterpenes from the spores of Ganoderma lucidum and their cytotoxicity against meth-A and LLC tumor cells.[Pubmed:10923835]

Chem Pharm Bull (Tokyo). 2000 Jul;48(7):1026-33.

Six new highly oxygenated lanostane-type triterpenes, called ganoderic acid gamma (1), ganoderic acid delta (2), Ganoderic acid Epsilon (3), ganoderic acid zeta (4), ganoderic acid eta (5) and ganoderic acid theta (6), were isolated from the spores of Ganoderma lucidum, together with known ganolucidic acid D (7) and ganoderic acid C2 (8). Their structures of the new triterpenes were determined as (23S)-7beta,15alpha,23-trihydroxy-3,11-dioxolanosta-8, 24(E)-diene-26-oic acid (1), (23S)-7alpha,15alpha23-trihydroxy-3,11-dioxolanosta-8, 24(E)-diene-26-oic acid (2), (23S)-3beta3,7beta, 23-trihydroxy-11,15-dioxolanosta-8,24(E)-diene-26-oic acid (3), (23S)-3beta,23-dihydroxy-7,11,15-trioxolanosta-8, 24(E)-diene-26-oic acid (4), (23S)-3beta,7beta,12beta,23-tetrahydroxy-11,15-dioxolanos ta-8,24(E)-diene-26-oic acid (5) and (23S)-3beta,12beta23-trihydroxy-7,11,15-trioxolanosta-8,24(E )-diene-26-oic acid (6), respectively, by chemical and spectroscopic means, which included the determination of a chiral center in the side chain by a modification of Mosher's method. The cytotoxicity of the compounds isolated from the Ganoderma spores was carried out in vitro against Meth-A and LLC tumor cell lines.

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