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Ganolucidic acid E

CAS# 114567-50-9

Ganolucidic acid E

Catalog No. BCX0032----Order now to get a substantial discount!

Product Name & Size Price Stock
Ganolucidic acid E: 5mg $357 In Stock
Ganolucidic acid E: 10mg Please Inquire In Stock
Ganolucidic acid E: 20mg Please Inquire Please Inquire
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Ganolucidic acid E: 500mg Please Inquire Please Inquire
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Quality Control of Ganolucidic acid E

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Chemical structure

Ganolucidic acid E

Chemical Properties of Ganolucidic acid E

Cas No. 114567-50-9 SDF Download SDF
PubChem ID N/A Appearance Powder
Formula C30H44O5 M.Wt 484.7
Type of Compound Triterpenoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Ganolucidic acid E

The fruit body of Ganoderma lucidum

Ganolucidic acid E Dilution Calculator

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Ganolucidic acid E Molarity Calculator

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Preparing Stock Solutions of Ganolucidic acid E

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.0631 mL 10.3157 mL 20.6313 mL 41.2626 mL 51.5783 mL
5 mM 0.4126 mL 2.0631 mL 4.1263 mL 8.2525 mL 10.3157 mL
10 mM 0.2063 mL 1.0316 mL 2.0631 mL 4.1263 mL 5.1578 mL
50 mM 0.0413 mL 0.2063 mL 0.4126 mL 0.8253 mL 1.0316 mL
100 mM 0.0206 mL 0.1032 mL 0.2063 mL 0.4126 mL 0.5158 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Ganolucidic acid E

Distinct Responses of Cytotoxic Ganoderma lucidum Triterpenoids in Human Carcinoma Cells.[Pubmed:26292672]

Phytother Res. 2015 Nov;29(11):1744-52.

The medicinal mushroom Ganoderma lucidum is well recognized for its effective cancer-preventative and therapeutic properties, while specific components responsible for these anticancer effects are not well studied. Six triterpenoids that are Ganolucidic acid E, lucidumol A, ganodermanontriol, 7-oxo-ganoderic acid Z, 15-hydroxy-ganoderic acid S, and ganoderic acid DM were isolated and identified from an extract of the mushroom. All compounds reduced cell growth in three human carcinoma cells (Caco-2, HepG2, and HeLa cells) dose dependently with LC50s from 20.87 to 84.36 muM. Moreover, the six compounds induced apoptosis in HeLa cells with a maximum increase (22%) of sub-G1 accumulations and 43.03% apoptotic cells in terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) assay (15-hydroxy-ganoderic acid S treatment). Apoptosis was further confirmed by annexin-V staining. Four of the compounds also caused apoptosis in Caco-2 cells with maximum 9.5% increase of sub-G1 accumulations (7-oxo-ganoderic acid Z treatment) and maximum 29.84% apoptotic cells in TUNEL assay (ganoderic acid DM treatment). Contrarily, none of the compounds induced apoptosis in HepG2 cells. The different responses of the three cell lines following these treatments indicated that the bioactive properties of these compounds may vary from cells of different sites of origin and are likely acting under diverse regulatory mechanisms.

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