Guaiacol salicylateCAS# 87-16-1 |
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| Cas No. | 87-16-1 | SDF | Download SDF |
| PubChem ID | 66596 | Appearance | Powder |
| Formula | C14H12O4 | M.Wt | 244.25 |
| Type of Compound | N/A | Storage | Desiccate at -20°C |
| Synonyms | 2-Methoxyphenyl salicylate;Guaiacol salol | ||
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | (2-methoxyphenyl) 2-hydroxybenzoate | ||
| SMILES | COC1=CC=CC=C1OC(=O)C2=CC=CC=C2O | ||
| Standard InChIKey | APMWEQQELZTXTL-UHFFFAOYSA-N | ||
| Standard InChI | InChI=1S/C14H12O4/c1-17-12-8-4-5-9-13(12)18-14(16)10-6-2-3-7-11(10)15/h2-9,15H,1H3 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
Guaiacol salicylate Dilution Calculator
Guaiacol salicylate Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 4.0942 mL | 20.4708 mL | 40.9417 mL | 81.8833 mL | 102.3541 mL |
| 5 mM | 0.8188 mL | 4.0942 mL | 8.1883 mL | 16.3767 mL | 20.4708 mL |
| 10 mM | 0.4094 mL | 2.0471 mL | 4.0942 mL | 8.1883 mL | 10.2354 mL |
| 50 mM | 0.0819 mL | 0.4094 mL | 0.8188 mL | 1.6377 mL | 2.0471 mL |
| 100 mM | 0.0409 mL | 0.2047 mL | 0.4094 mL | 0.8188 mL | 1.0235 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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[The physiologic disposition and pharmacokinetics of guaiacol acetylsalicylate in rats].[Pubmed:2092574]
Yao Xue Xue Bao. 1990;25(9):664-9.
Guaiacol acetylsalicylate (GASL) has been shown to possess significant anti-inflammatory, antipyretic and expectorant activities and has been used clinically in chronic bronchitis with fairly good results. In the present work, the absorption, distribution and excretion of metabolites of the drug were studied in rats using quantitative TLC scanning technique. GASL was shown to be unstable in rat gastrointestinal tract and Guaiacol salicylate (GSLT) and salicylic acid (SLA) were found in plasma. The plasma SLA concentration-time curve obtained after oral administration of GASL to rats was shown to fit a one compartment open model with the following pharmacokinetic parameters: T1/2ka = 1.25 h, T1/2ke = 3.28 h, ka = 0.5554/h, ke = 0.2111/h, Tmax = 3.02 h, Cmax = 331.46 micrograms/ml, AUC = 2832.93 micrograms/ml.h The SLA concentration was found to be high in muscle, moderate in spleen, testicle, kidney, lung, plasma, heart and liver and low in brain. The GSLT concentration was found to be low in plasma and organs. Within 24 h following ig administration of GASL the total SLA excreted in urine and feces was 10.9 and 0.41 of the GASL dose, respectively.
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