8-O-Methylretusin-7-O-beta-D-glucopyranosideCAS# 68862-13-5 |
Quality Control & MSDS
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| Cas No. | 68862-13-5 | SDF | Download SDF |
| PubChem ID | 131637615 | Appearance | Powder |
| Formula | C23H24O10 | M.Wt | 460.43 |
| Type of Compound | Flavonoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | 8-methoxy-3-(4-methoxyphenyl)-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one | ||
| SMILES | COC1=CC=C(C=C1)C2=COC3=C(C2=O)C=CC(=C3OC)OC4C(C(C(C(O4)CO)O)O)O | ||
| Standard InChIKey | WTXMHYXTGODDJX-PUIBNRJISA-N | ||
| Standard InChI | InChI=1S/C23H24O10/c1-29-12-5-3-11(4-6-12)14-10-31-21-13(17(14)25)7-8-15(22(21)30-2)32-23-20(28)19(27)18(26)16(9-24)33-23/h3-8,10,16,18-20,23-24,26-28H,9H2,1-2H3/t16-,18-,19+,20-,23-/m1/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | 1. 8-O-Methylretusin-7-O-beta-D-glucopyranoside shows significant antimicrobial activity with a broad spectrum as well as antioxidant activity . |
| Targets | Antifection |
8-O-Methylretusin-7-O-beta-D-glucopyranoside Dilution Calculator
8-O-Methylretusin-7-O-beta-D-glucopyranoside Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.1719 mL | 10.8594 mL | 21.7188 mL | 43.4377 mL | 54.2971 mL |
| 5 mM | 0.4344 mL | 2.1719 mL | 4.3438 mL | 8.6875 mL | 10.8594 mL |
| 10 mM | 0.2172 mL | 1.0859 mL | 2.1719 mL | 4.3438 mL | 5.4297 mL |
| 50 mM | 0.0434 mL | 0.2172 mL | 0.4344 mL | 0.8688 mL | 1.0859 mL |
| 100 mM | 0.0217 mL | 0.1086 mL | 0.2172 mL | 0.4344 mL | 0.543 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Phenolic compounds from Halimodendron halodendron (Pall.) voss and their antimicrobial and antioxidant activities.[Pubmed:23109858]
Int J Mol Sci. 2012;13(9):11349-64.
Halimodendron halodendron has been used as forage in northwestern China for a long time. Its young leaves and flowers are edible and favored by indigenous people. In this study, eleven phenolic compounds were bioassay-guided and isolated from the aerial parts of H. halodendron for the first time. They were identified by means of physicochemical and spectrometric analysis as quercetin (1), 3,5,7,8,4'-pentahydroxy-3'-methoxy flavone (2), 3-O-methylquercetin (3), 3,3'-di-O-methylquercetin (4), 3,3'-di-O-methylquercetin-7-O-beta-d-glucopyranoside (5), isorhamentin-3-O-beta-d-rutinoside (6), 8-O-methylretusin (7), 8-O-Methylretusin-7-O-beta-D-glucopyranoside (8), salicylic acid (9), p-hydroxybenzoic acid (ferulic acid) (10), and 4-hydroxy-3-methoxy cinnamic acid (11). They were sorted as flavonols (1-6), soflavones (7 and 8), and phenolic acids (9-11). Among the compounds, flanools 1-4 revealed a strong antibacterial activity with minimum inhibitory concentration (MIC) values of 50-150 mug/mL, and median inhibitory concentration (IC(50)) values of 26.8-125.1 mug/mL. The two isoflavones (7 and 8) showed moderate inhibitory activity on the test bacteria. Three phenolic acids (9, 10 and 11) showed strong antibacterial activity with IC(50) values of 28.1-149.7 mug/mL. Antifungal activities of the compounds were similar to their antibacterial activities. All these phenolic compounds showed significant antimicrobial activity with a broad spectrum as well as antioxidant activity based on 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging and beta-carotene-linoleic acid bleaching assays. In general, the flavonol aglycones with relatively low polarity exhibited stronger activities than the glycosides. The results suggest the potential of this plant as a source of functional food ingredients and provide support data for its utilization as forage as well.
