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Ilexgenin B

CAS# 109008-39-1

Ilexgenin B

2D Structure

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Ilexgenin B

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Chemical Properties of Ilexgenin B

Cas No. 109008-39-1 SDF Download SDF
PubChem ID N/A Appearance Powder
Formula C30H48O4 M.Wt 472.71
Type of Compound N/A Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Ilexgenin B Dilution Calculator

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Ilexgenin B Molarity Calculator

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Preparing Stock Solutions of Ilexgenin B

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.1155 mL 10.5773 mL 21.1546 mL 42.3092 mL 52.8865 mL
5 mM 0.4231 mL 2.1155 mL 4.2309 mL 8.4618 mL 10.5773 mL
10 mM 0.2115 mL 1.0577 mL 2.1155 mL 4.2309 mL 5.2887 mL
50 mM 0.0423 mL 0.2115 mL 0.4231 mL 0.8462 mL 1.0577 mL
100 mM 0.0212 mL 0.1058 mL 0.2115 mL 0.4231 mL 0.5289 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Ilexgenin B

Antiplatelet aggregation triterpene saponins from the barks of Ilex rotunda.[Pubmed:25447155]

Fitoterapia. 2015 Mar;101:19-26.

Four new triterpene saponins, rotundinosides A-D (1-4) and seven known triterpene saponins (5-11) were isolated from a methanol extract of the barks of Ilex rotunda Thunb. The new saponins were characterized as 3-O-beta-d-glucopyranosy1-(1-->2)-beta-d-xylopyranosyl siaresinolic acid 28-O-beta-d-glucopyranoside (1), 3-O-[beta-d-glucopyranosy1-(1-->2)-beta-d-xylopyranosyl]-3beta,19alpha-dihydroxyurs-12-en-28-oic-O-beta-d-glucopranosy1ester (2), 3-O-[alpha-l-rhamnopyranosyl-(1-->2)-beta-d-glucopyranosy1-(1-->2)-alpha-l-arabinopyranosyl]-3beta,19alpha-dihydroxyurs-12-en-28-oic-O-beta-d-glucopyranosy1 ester (3), and 3-O-alpha-l-rhamanopyranosyl-(1-->2)-beta-d-glucopyranosy1-(1-->2)-alpha-l-arabinopyranosyl Ilexgenin B 28-O-beta-d-glucopyranosy1 ester (4), respectively. Their structures were established by extensive spectroscopic analysis, including HSQC, HMBC, (1)H-(1)H COSY, NOESY and acid hydrolysis, and also by the comparison of their spectroscopic data with those of related compounds. The known compounds 5-11 were all obtained from this species for the first time. The biological activity of compounds 1-11 against ADP induced platelet aggregation in rabbit plasma was determined. Among the tested compounds 1, 3, 5 and 10 exhibited strong inhibition of platelet aggregation in vitro, with IC50 values of 11.4+/-2.2, 10.4+/-1.3, 13.2+/-2.4, and 15.1+/-3.4muM, respectively.

Triterpenoid saponins from Ilex mamillata C.Y. Wu ex C.J. Tseng.[Pubmed:22124275]

Nat Prod Res. 2012 Nov;26(21):1991-5.

Two new triterpenoid saponins, ilemaminosides A and B (1 and 2) along with six known saponins (3-8) were isolated from 70% ethanolic extract of the leaves of Ilex mamillata C.Y. Wu ex C.J. Tseng. The new saponins were characterised as 3-O-alpha-L-arabinopyranosyl-Ilexgenin B (1) and 3-O-beta-D-glucopyranosyl-(1 --> 3)-alpha-L-arabinopyranosyl-Ilexgenin B (2). The structures of compounds 1 and 2 were elucidated on the basis of the chemical and spectroscopic methods, and the structures of known compounds were identified by comparison of their spectroscopic data with those reported in the literature. The compounds showed inhibitory activities in anti-inflammatory assay in vitro with IC(50) values in the range 25.37-38.33 microg mL(-1).

Two new triterpenoid saponins from the root of Ilex pubescens.[Pubmed:18058383]

J Asian Nat Prod Res. 2008 Jan-Feb;10(1-2):71-5.

Two new triterpenoid saponins, named ilexsaponins B(4) (1) and C (2), have been isolated from the roots of Ilex pubescens. Their structures have been established as Ilexgenin B 3-O-alpha-L-arabinopyranosyl-(2-->1)-beta-D-glucopyranosyl-(2-->1)-beta-D-xylopyranoside (1) and 3-O-beta-D-xylopyranosyl spathodic acid 28-beta-D-glucopyranosyl ester (2) by means of spectral and chemical methods.

Triterpenoid saponins from Ilex latifolia.[Pubmed:9887534]

Phytochemistry. 1998 Dec;49(8):2483-6.

Three new triterpenoid saponins, latifolosides F, G, H were isolated from the leaves of Ilex latifolia. Their structures were elucidated on the basis of chemical and spectral evidence. Latifoloside F was determined to be 3-O-[alpha-L-rhamnopyranosyl(1-2)]-[beta-D-glucopyranosyl(1-3)-]- alpha-L-arabinopyranosyl Ilexgenin B 28-O-[alpha-L-rhamnopyranosyl(1-2)]-beta-D-glucopyranoside. Latifoloside G was 3-O-[alpha-L-rhamnopyranosyl(1-2)]-[beta-D-glucopyranosyl(1-3)-]- alpha-L-arabinopyranosyl pomolic acid 28-O-[alpha-L-rhamnopyranosyl(1-2)]-beta-D-glucopyranoside. Latifolioside H(3) was 3-O-[alpha-L-rhamnopyranosyl(1-2)]-[beta-D-glucopyranosyl(1-3)-]- alpha-L-arabinopyranosyl siaresinolic acid 28-O-[alpha-L-rhamnopyranosyl(1-2)]-beta-D-glucopyranoside.

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