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(+)-Medicarpin

CAS# 33983-40-3

(+)-Medicarpin

2D Structure

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3D structure

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(+)-Medicarpin

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Chemical Properties of (+)-Medicarpin

Cas No. 33983-40-3 SDF Download SDF
PubChem ID 623060.0 Appearance Powder
Formula C16H14O4 M.Wt 270.28
Type of Compound N/A Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 9-methoxy-6a,11a-dihydro-6H-[1]benzofuro[3,2-c]chromen-3-ol
SMILES COC1=CC2=C(C=C1)C3COC4=C(C3O2)C=CC(=C4)O
Standard InChIKey NSRJSISNDPOJOP-UHFFFAOYSA-N
Standard InChI InChI=1S/C16H14O4/c1-18-10-3-5-11-13-8-19-14-6-9(17)2-4-12(14)16(13)20-15(11)7-10/h2-7,13,16-17H,8H2,1H3
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

(+)-Medicarpin Dilution Calculator

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(+)-Medicarpin Molarity Calculator

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Preparing Stock Solutions of (+)-Medicarpin

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.6999 mL 18.4993 mL 36.9987 mL 73.9973 mL 92.4967 mL
5 mM 0.74 mL 3.6999 mL 7.3997 mL 14.7995 mL 18.4993 mL
10 mM 0.37 mL 1.8499 mL 3.6999 mL 7.3997 mL 9.2497 mL
50 mM 0.074 mL 0.37 mL 0.74 mL 1.4799 mL 1.8499 mL
100 mM 0.037 mL 0.185 mL 0.37 mL 0.74 mL 0.925 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on (+)-Medicarpin

[A new benzopyran glycoside from Gentiana macrophylla].[Pubmed:38403317]

Zhongguo Zhong Yao Za Zhi. 2024 Jan;49(2):412-419.

Thirteen compounds were isolated and identified from 70% ethanol extract of the roots of Gentiana macrophylla by multi-chromatographic methods, including microporous resin, silica gel, and C_(18) reversed-phase column chromatography, as well as HPLC as follows: macrophylloside G(1), macrophylloside D(2), 5-formyl-2,3-dihydroisocoumarin(3),(+)-Medicarpin(4),(+)-syringaresinol(5), liquiritigenin(6),(3R)-sativanone(7),(3R)-3'-O-methylviolanone(8), 4,2',4'-trihydroxychalcone(9), latifolin(10), gentioxepine(11), 6alpha-hydroxycyclonerolidol(12), and ethyl linoleate(13). Compound 1 was a new benzopyran glycoside. Compounds 4, 6-10, 12, and 13 were isolated for the first time from Gentiana plants. Compounds 1 and 2 showed promising hepatoprotective activity against D-GalN-induced AML12 cell damage at the concentration of 10 mumol.L~(-1), and compound 2 exhibited more significant activity than silybin at the same concentration.

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