Lochnericine

CAS# 72058-36-7

Lochnericine

Catalog No. BCN4595----Order now to get a substantial discount!

Product Name & Size Price Stock
Lochnericine: 5mg Please Inquire In Stock
Lochnericine: 10mg Please Inquire In Stock
Lochnericine: 20mg Please Inquire Please Inquire
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Quality Control of Lochnericine

Number of papers citing our products

Chemical structure

Lochnericine

3D structure

Chemical Properties of Lochnericine

Cas No. 72058-36-7 SDF Download SDF
PubChem ID 11382599 Appearance Powder
Formula C21H24N2O3 M.Wt 352.43
Type of Compound Alkaloids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
SMILES CCC12CC(=C3C4(C1N(CC4)CC5C2O5)C6=CC=CC=C6N3)C(=O)OC
Standard InChIKey AUVZFRDLRJQTQF-KXEYLTKFSA-N
Standard InChI InChI=1S/C21H24N2O3/c1-3-20-10-12(18(24)25-2)16-21(13-6-4-5-7-14(13)22-16)8-9-23(19(20)21)11-15-17(20)26-15/h4-7,15,17,19,22H,3,8-11H2,1-2H3/t15-,17-,19-,20+,21-/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Lochnericine

The herbs of Catharanthus roseus (L.)G.Don

Biological Activity of Lochnericine

Description1. Lochnericine (LOC) is a component of Voacanga africana, which is a type of traditional medical food in Africa widely used for treating diseases.

Lochnericine Dilution Calculator

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Lochnericine Molarity Calculator

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Preparing Stock Solutions of Lochnericine

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.8374 mL 14.1872 mL 28.3744 mL 56.7489 mL 70.9361 mL
5 mM 0.5675 mL 2.8374 mL 5.6749 mL 11.3498 mL 14.1872 mL
10 mM 0.2837 mL 1.4187 mL 2.8374 mL 5.6749 mL 7.0936 mL
50 mM 0.0567 mL 0.2837 mL 0.5675 mL 1.135 mL 1.4187 mL
100 mM 0.0284 mL 0.1419 mL 0.2837 mL 0.5675 mL 0.7094 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Lochnericine

Spectroscopy and docking simulations of the interaction between lochnericine and bovine serum albumin.[Pubmed:24942935]

Luminescence. 2015 Mar;30(2):240-6.

Lochnericine (LOC) is a component of Voacanga africana, which is a type of traditional medical food in Africa widely used for treating diseases. In this article, the interaction between LOC and bovine serum albumin (BSA) was studied by fluorescence spectroscopy. Furthermore, Fourier transform infrared (FTIR), Raman and circular dichroism (CD) were used to investigate the structural changes of BSA. The experimental results consistently indicated that LOC changed the secondary structure of BSA. Three structure-similar components were used to study the interference experiments. The molecular modeling results showed that LOC could bind within not only sites I and II, but also bind the cavity of subdomain IB.

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