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2-Hydroxyplatyphyllide

CAS# 72145-19-8

2-Hydroxyplatyphyllide

Catalog No. BCN7119----Order now to get a substantial discount!

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Chemical structure

2-Hydroxyplatyphyllide

3D structure

Chemical Properties of 2-Hydroxyplatyphyllide

Cas No. 72145-19-8 SDF Download SDF
PubChem ID 14681768 Appearance Powder
Formula C14H14O3 M.Wt 230.26
Type of Compound Sesquiterpenoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (1R,11R)-6-hydroxy-11-prop-1-en-2-yl-2-oxatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-3-one
SMILES CC(=C)C1CCC2=C3C1OC(=O)C3=CC(=C2)O
Standard InChIKey BUSWPFRBQXQTLO-ZWNOBZJWSA-N
Standard InChI InChI=1S/C14H14O3/c1-7(2)10-4-3-8-5-9(15)6-11-12(8)13(10)17-14(11)16/h5-6,10,13,15H,1,3-4H2,2H3/t10-,13-/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of 2-Hydroxyplatyphyllide

The roots of Ligularia songarica.

Biological Activity of 2-Hydroxyplatyphyllide

Description2-Hydroxyplatyphyllide is a natural product from Ligularia songarica.

Protocol of 2-Hydroxyplatyphyllide

Structure Identification
Zhong Yao Cai. 2014 Oct;37(10):1789-92.

Chemical constituents of Ligularia songarica.[Pubmed: 25895384]

To study the chemical constituents of Ligularia songarica.
METHODS AND RESULTS:
Isolation and purification were carried out on repeated silica gel column chromatography. The compounds structures were identified by physico-chemical properties and spectral analyses. Ten compounds were isolated and identified as benzofuranoeremophil-2-ene (1), 6-angeloyloxy-1,10-epoxy-euryopsin (2), 2-Hydroxyplatyphyllide (3), 1β-hydroxy-6,9-dien-8-oxoeremophy-11-nor-11-ketone (4), 2-isopropenyl-6-acetyl-8-methoxy-13-benzodioxin-4-one (5), 1β-hydroxy-6,9-dien-8-oxo-11-nor-11-hydroxyeremophilane (6), isopetasin (7), 6β,10α-dihydroxy-1-oxoeremophila-7 (11), 8(9)-diene-8,12-olide (8), 10α-hydroxy-1-oxo-eremophila-7 (11), 8(9)-diene-8,12-olide (9) and 6β-angeloyloxy-1β,10β-epoxy-9-oxo-furaneremophilane (10).
CONCLUSIONS:
Compounds 2-9 are obtained from this plant for the first time.

2-Hydroxyplatyphyllide Dilution Calculator

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Preparing Stock Solutions of 2-Hydroxyplatyphyllide

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 4.3429 mL 21.7146 mL 43.4292 mL 86.8583 mL 108.5729 mL
5 mM 0.8686 mL 4.3429 mL 8.6858 mL 17.3717 mL 21.7146 mL
10 mM 0.4343 mL 2.1715 mL 4.3429 mL 8.6858 mL 10.8573 mL
50 mM 0.0869 mL 0.4343 mL 0.8686 mL 1.7372 mL 2.1715 mL
100 mM 0.0434 mL 0.2171 mL 0.4343 mL 0.8686 mL 1.0857 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on 2-Hydroxyplatyphyllide

[Chemical constituents of Ligularia songarica].[Pubmed:25895384]

Zhong Yao Cai. 2014 Oct;37(10):1789-92.

OBJECTIVE: To study the chemical constituents of Ligularia songarica. METHODS: Isolation and purification were carried out on repeated silica gel column chromatography. The compounds structures were identified by physico-chemical properties and spectral analyses. RESULTS: Ten compounds were isolated and identified as benzofuranoeremophil-2-ene (1), 6-angeloyloxy-1,10-epoxy-euryopsin (2), 2-Hydroxyplatyphyllide (3), 1beta-hydroxy-6,9-dien-8-oxoeremophy-11-nor-11-ketone (4), 2-isopropenyl-6-acetyl-8-methoxy-13-benzodioxin-4-one (5), 1beta-hydroxy-6,9-dien-8-oxo-11-nor-11-hydroxyeremophilane (6), isopetasin (7), 6beta,10alpha-dihydroxy-1-oxoeremophila-7 (11), 8(9)-diene-8,12-olide (8), 10alpha-hydroxy-1-oxo-eremophila-7 (11), 8(9)-diene-8,12-olide (9) and 6beta-angeloyloxy-1beta,10beta-epoxy-9-oxo-furaneremophilane (10). CONCLUSION: Compounds 2-9 are obtained from this plant for the first time.

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