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2alpha-Hydroxyeupatolide 8-O-angelate

CAS# 72229-39-1

2alpha-Hydroxyeupatolide 8-O-angelate

Catalog No. BCN7340----Order now to get a substantial discount!

Product Name & Size Price Stock
2alpha-Hydroxyeupatolide 8-O-angelate: 5mg $886 In Stock
2alpha-Hydroxyeupatolide 8-O-angelate: 10mg Please Inquire In Stock
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Chemical structure

2alpha-Hydroxyeupatolide 8-O-angelate

3D structure

Chemical Properties of 2alpha-Hydroxyeupatolide 8-O-angelate

Cas No. 72229-39-1 SDF Download SDF
PubChem ID 131858140 Appearance Powder
Formula C20H26O5 M.Wt 346.42
Type of Compound Sesquiterpenoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name [(3aR,4R,6Z,8S,10E,11aR)-8-hydroxy-6,10-dimethyl-3-methylidene-2-oxo-3a,4,5,8,9,11a-hexahydrocyclodeca[b]furan-4-yl] (Z)-2-methylbut-2-enoate
SMILES CC=C(C)C(=O)OC1CC(=CC(CC(=CC2C1C(=C)C(=O)O2)C)O)C
Standard InChIKey ZYKRXWIPMUJNME-NJYQSCQOSA-N
Standard InChI InChI=1S/C20H26O5/c1-6-13(4)19(22)24-16-9-11(2)7-15(21)8-12(3)10-17-18(16)14(5)20(23)25-17/h6-7,10,15-18,21H,5,8-9H2,1-4H3/b11-7-,12-10+,13-6-/t15-,16-,17-,18-/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of 2alpha-Hydroxyeupatolide 8-O-angelate

The herbs of Eupatorium chinense var. tozanense.

Biological Activity of 2alpha-Hydroxyeupatolide 8-O-angelate

Description2alpha-Hydroxyeupatolide 8-O-angelate is a natural product from Eupatorium chinense var. tozanense.

Protocol of 2alpha-Hydroxyeupatolide 8-O-angelate

Structure Identification
Helvetica Chimica Acta, 2010, 91(11):2115-2121.

Eupatozansins A-C, Sesquiterpene Lactones from Eupatorium chinense var. tozanense[Reference: WebLink]


METHODS AND RESULTS:
Phytochemical investigation of Eupatorium chinense var. tozanense has resulted in the isolation of three new germacranolides, designated as eupatozansins A–C (1–3), along with five known compounds, (5S,6R,7R,8R)-8-angeloyloxy-2-oxoguaia-1(10),3,11(13)-trien-12,6-olide (4), costunolide (5), leptocarpin (6), 2alpha-Hydroxyeupatolide 8-O-angelate (7), and quercetin (8).
CONCLUSIONS:
The structures of the new compounds were identified by 1D and 2D NMR experiments, as well as high-resolution mass spectrometry. The in vitro cytotoxic activities of compounds 1–8 were evaluated.

2alpha-Hydroxyeupatolide 8-O-angelate Dilution Calculator

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2alpha-Hydroxyeupatolide 8-O-angelate Molarity Calculator

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Preparing Stock Solutions of 2alpha-Hydroxyeupatolide 8-O-angelate

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.8867 mL 14.4333 mL 28.8667 mL 57.7334 mL 72.1667 mL
5 mM 0.5773 mL 2.8867 mL 5.7733 mL 11.5467 mL 14.4333 mL
10 mM 0.2887 mL 1.4433 mL 2.8867 mL 5.7733 mL 7.2167 mL
50 mM 0.0577 mL 0.2887 mL 0.5773 mL 1.1547 mL 1.4433 mL
100 mM 0.0289 mL 0.1443 mL 0.2887 mL 0.5773 mL 0.7217 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on 2alpha-Hydroxyeupatolide 8-O-angelate

Eupatozansins A-C, Sesquiterpene Lactones from Eupatorium chinense var. tozanense

Helvetica Chimica Acta, 2010, 91(11):2115-2121.

Phytochemical investigation of Eupatorium chinense var. tozanense has resulted in the isolation of three new germacranolides, designated as eupatozansins A–C (1–3), along with five known compounds, (5S,6R,7R,8R)-8-angeloyloxy-2-oxoguaia-1(10),3,11(13)-trien-12,6-olide (4), costunolide (5), leptocarpin (6), 2alpha-Hydroxyeupatolide 8-O-angelate (7), and quercetin (8). The structures of the new compounds were identified by 1D and 2D NMR experiments, as well as high-resolution mass spectrometry. The in vitro cytotoxic activities of compounds 1–8 were evaluated.

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