Sepinol

CAS# 72061-63-3

Sepinol

Catalog No. BCN4277----Order now to get a substantial discount!

Product Name & Size Price Stock
Sepinol: 5mg $989 In Stock
Sepinol: 10mg Please Inquire In Stock
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Quality Control of Sepinol

Number of papers citing our products

Chemical structure

Sepinol

3D structure

Chemical Properties of Sepinol

Cas No. 72061-63-3 SDF Download SDF
PubChem ID 91884832 Appearance Powder
Formula C16H14O7 M.Wt 318.3
Type of Compound Flavonoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (2R,3R)-2-(3,5-dihydroxy-4-methoxyphenyl)-3,7-dihydroxy-2,3-dihydrochromen-4-one
SMILES COC1=C(C=C(C=C1O)C2C(C(=O)C3=C(O2)C=C(C=C3)O)O)O
Standard InChIKey AFCZAKZBCYSVSS-LSDHHAIUSA-N
Standard InChI InChI=1S/C16H14O7/c1-22-16-10(18)4-7(5-11(16)19)15-14(21)13(20)9-3-2-8(17)6-12(9)23-15/h2-6,14-15,17-19,21H,1H3/t14-,15+/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Sepinol

The herbs of Sophora viciifolia

Biological Activity of Sepinol

In vitro

P22 Discovery of new bioactive compounds from (Dioclea reflexa Hook F.): Effective constituents of a traditional herbal medicine.[Reference: WebLink]

Biochemical Pharmacology, 2017, 139:132.


METHODS AND RESULTS:
Three new flavonoids, reflevone 1, lexaflavanone 2 and lexaflavanol 3, together with, mearnsetin 4, 7,4’-dihydroxyflavone 5, Sepinol 6, pallasin 7, 4-OMGA (3, 5-dihydroxyl-4-methoxylbenzoic acid) 8, Lupeol 9, Hederagenin 10 and a rare dipeptide, auratiamide acetate 11 were isolated from the ethyl acetate soluble part of the ethanolic root extract of Dioclea reflexa. Structures of the isolated compounds were elucidated by 1 and 2-dimensional NMR spectroscopy. The secondary metabolites were selectively examined for immunomodulatory, urease inhibitory, lypoxigenase inhibitory and free radical scavenging activities. Additionally, an in vitro cytotoxicity bioassay was carried on human non small cell lung cancer (NCI-H460).
CONCLUSIONS:
Our findings suggest that various activities of the new metabolites may indicate pharmacological potential against immune disorders, gastrointestinal ulcers and oxidative stress diseases.

Sepinol Dilution Calculator

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Sepinol Molarity Calculator

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Preparing Stock Solutions of Sepinol

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.1417 mL 15.7085 mL 31.4169 mL 62.8338 mL 78.5423 mL
5 mM 0.6283 mL 3.1417 mL 6.2834 mL 12.5668 mL 15.7085 mL
10 mM 0.3142 mL 1.5708 mL 3.1417 mL 6.2834 mL 7.8542 mL
50 mM 0.0628 mL 0.3142 mL 0.6283 mL 1.2567 mL 1.5708 mL
100 mM 0.0314 mL 0.1571 mL 0.3142 mL 0.6283 mL 0.7854 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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