LudaconitineCAS# 82144-72-7 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
Cas No. | 82144-72-7 | SDF | Download SDF |
PubChem ID | 138911430.0 | Appearance | Powder |
Formula | C32H45NO9 | M.Wt | 587.71 |
Type of Compound | Alkaloids | Storage | Desiccate at -20°C |
Synonyms | 14-benzoylpseudaconine | ||
Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
Chemical Name | [(2R,3R,4R,5S,6S,8R,13R,14R,16S,17S,18R)-11-ethyl-5,8,14-trihydroxy-6,16,18-trimethoxy-13-(methoxymethyl)-11-azahexacyclo[7.7.2.12,5.01,10.03,8.013,17]nonadecan-4-yl] benzoate | ||
SMILES | CCN1CC2(C(CC(C34C2C(C(C31)C5(CC(C6(CC4C5C6OC(=O)C7=CC=CC=C7)O)OC)O)OC)OC)O)COC | ||
Standard InChIKey | WCJLKJORIRSXRT-DDEDXNQJSA-N | ||
Standard InChI | InChI=1S/C32H45NO9/c1-6-33-15-29(16-38-2)19(34)12-20(39-3)32-18-13-30(36)21(40-4)14-31(37,23(26(32)33)24(41-5)25(29)32)22(18)27(30)42-28(35)17-10-8-7-9-11-17/h7-11,18-27,34,36-37H,6,12-16H2,1-5H3/t18-,19-,20+,21+,22-,23?,24+,25-,26?,27-,29+,30+,31-,32?/m1/s1 | ||
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
||
About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
||
Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. |
Ludaconitine Dilution Calculator
Ludaconitine Molarity Calculator
1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
1 mM | 1.7015 mL | 8.5076 mL | 17.0152 mL | 34.0304 mL | 42.538 mL |
5 mM | 0.3403 mL | 1.7015 mL | 3.403 mL | 6.8061 mL | 8.5076 mL |
10 mM | 0.1702 mL | 0.8508 mL | 1.7015 mL | 3.403 mL | 4.2538 mL |
50 mM | 0.034 mL | 0.1702 mL | 0.3403 mL | 0.6806 mL | 0.8508 mL |
100 mM | 0.017 mL | 0.0851 mL | 0.1702 mL | 0.3403 mL | 0.4254 mL |
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. |
Calcutta University
University of Minnesota
University of Maryland School of Medicine
University of Illinois at Chicago
The Ohio State University
University of Zurich
Harvard University
Colorado State University
Auburn University
Yale University
Worcester Polytechnic Institute
Washington State University
Stanford University
University of Leipzig
Universidade da Beira Interior
The Institute of Cancer Research
Heidelberg University
University of Amsterdam
University of Auckland
TsingHua University
The University of Michigan
Miami University
DRURY University
Jilin University
Fudan University
Wuhan University
Sun Yat-sen University
Universite de Paris
Deemed University
Auckland University
The University of Tokyo
Korea University
- (-)-3-Demethylcolchicine
Catalog No.:BCX1192
CAS No.:7336-33-6
- Daucosterin acetate
Catalog No.:BCX1191
CAS No.:4282-00-2
- Deoxycytidine
Catalog No.:BCX1190
CAS No.:951-77-9
- Kissoone A
Catalog No.:BCX1189
CAS No.:903559-01-3
- Glycyrrhizic acid methyl ester
Catalog No.:BCX1188
CAS No.:104191-95-9
- Rubropunctamine
Catalog No.:BCX1187
CAS No.:514-66-9
- Neoisoliquiritigenin
Catalog No.:BCX1186
CAS No.:7014-39-3
- 6-Acetyl-7-hydroxy-2,3-dimethylchromone
Catalog No.:BCX1185
CAS No.:225518-70-7
- Heterophyllin J
Catalog No.:BCX1184
CAS No.:660397-15-9
- 5-Methoxyafrormosin 7-O-glucoside
Catalog No.:BCX1183
CAS No.:64656-92-4
- Acetylarenobufagin
Catalog No.:BCX1182
CAS No.:184673-79-8
- N-Acetyl-D-lactosamine
Catalog No.:BCX1181
CAS No.:32181-59-2
- Syringopicroside
Catalog No.:BCX1194
CAS No.:29118-80-7
- Taccalonolide C
Catalog No.:BCX1195
CAS No.:117803-96-0
- Complanatuside 6"-malonate
Catalog No.:BCX1196
CAS No.:2089462-18-8
- Resinacein C
Catalog No.:BCX1197
CAS No.:1309931-92-7
- Markogenin
Catalog No.:BCX1198
CAS No.:562-35-6
- 4α-Phorbol
Catalog No.:BCX1199
CAS No.:26241-63-4
- Alltride
Catalog No.:BCX1200
CAS No.:2050-87-5
- 21-keto-gypenoside A
Catalog No.:BCX1201
CAS No.:1392136-41-2
- Tigogenin lactone
Catalog No.:BCX1202
CAS No.:514-33-0
- 8-Keto-berberine
Catalog No.:BCX1203
CAS No.:81397-08-2
- Isoproprotogracillin B
Catalog No.:BCX1204
CAS No.:117457-34-8
- Iodixanol Impurity C
Catalog No.:BCX1205
CAS No.:171897-74-8
Antileishmanial diterpenoid alkaloids from Aconitum spicatum (Bruhl) Stapf.[Pubmed:26615865]
Nat Prod Res. 2016 Nov;30(22):2590-2593.
The crude extracts of tubers of Aconitum spicatum (Bruhl) Stapf were investigated for in vitro antileishmanial activity against Leishmania major. The dichloromethane extract at pH 2.5 showed antileishmanial activity with IC(50) value of 27.10 +/- 0.0 mug/mL. Chromatographic purification of the dichloromethane extract led to isolation of three C-19 norditerpenoid alkaloids indaconitine (1), chasmaconitine (2) and Ludaconitine (3). Compounds 3 and 2 showed antileishmanial activity with IC(50) = 36.10 +/- 3.4 and 56.30 +/- 2.1 mug/mL, respectively. Compound 1 was less effective (IC(50) > 100 mug/mL). The cytotoxicity of compounds 1, 2 and 3 studied against MCF7, HeLa and PC3 cancer cell lines and 3T3 normal fibroblast cell line did not show cytotoxicity at 30 muM.