Ludaconitine

CAS# 82144-72-7

Ludaconitine

Catalog No. BCX1193----Order now to get a substantial discount!

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Ludaconitine: 5mg Please Inquire In Stock
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Quality Control of Ludaconitine

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Chemical structure

Ludaconitine

3D structure

Chemical Properties of Ludaconitine

Cas No. 82144-72-7 SDF Download SDF
PubChem ID 138911430.0 Appearance Powder
Formula C32H45NO9 M.Wt 587.71
Type of Compound Alkaloids Storage Desiccate at -20°C
Synonyms 14-benzoylpseudaconine
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name [(2R,3R,4R,5S,6S,8R,13R,14R,16S,17S,18R)-11-ethyl-5,8,14-trihydroxy-6,16,18-trimethoxy-13-(methoxymethyl)-11-azahexacyclo[7.7.2.12,5.01,10.03,8.013,17]nonadecan-4-yl] benzoate
SMILES CCN1CC2(C(CC(C34C2C(C(C31)C5(CC(C6(CC4C5C6OC(=O)C7=CC=CC=C7)O)OC)O)OC)OC)O)COC
Standard InChIKey WCJLKJORIRSXRT-DDEDXNQJSA-N
Standard InChI InChI=1S/C32H45NO9/c1-6-33-15-29(16-38-2)19(34)12-20(39-3)32-18-13-30(36)21(40-4)14-31(37,23(26(32)33)24(41-5)25(29)32)22(18)27(30)42-28(35)17-10-8-7-9-11-17/h7-11,18-27,34,36-37H,6,12-16H2,1-5H3/t18-,19-,20+,21+,22-,23?,24+,25-,26?,27-,29+,30+,31-,32?/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Ludaconitine

Aconitum carmichaeli Debx.

Ludaconitine Dilution Calculator

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Ludaconitine Molarity Calculator

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Preparing Stock Solutions of Ludaconitine

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.7015 mL 8.5076 mL 17.0152 mL 34.0304 mL 42.538 mL
5 mM 0.3403 mL 1.7015 mL 3.403 mL 6.8061 mL 8.5076 mL
10 mM 0.1702 mL 0.8508 mL 1.7015 mL 3.403 mL 4.2538 mL
50 mM 0.034 mL 0.1702 mL 0.3403 mL 0.6806 mL 0.8508 mL
100 mM 0.017 mL 0.0851 mL 0.1702 mL 0.3403 mL 0.4254 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Ludaconitine

Antileishmanial diterpenoid alkaloids from Aconitum spicatum (Bruhl) Stapf.[Pubmed:26615865]

Nat Prod Res. 2016 Nov;30(22):2590-2593.

The crude extracts of tubers of Aconitum spicatum (Bruhl) Stapf were investigated for in vitro antileishmanial activity against Leishmania major. The dichloromethane extract at pH 2.5 showed antileishmanial activity with IC(50) value of 27.10 +/- 0.0 mug/mL. Chromatographic purification of the dichloromethane extract led to isolation of three C-19 norditerpenoid alkaloids indaconitine (1), chasmaconitine (2) and Ludaconitine (3). Compounds 3 and 2 showed antileishmanial activity with IC(50) = 36.10 +/- 3.4 and 56.30 +/- 2.1 mug/mL, respectively. Compound 1 was less effective (IC(50) > 100 mug/mL). The cytotoxicity of compounds 1, 2 and 3 studied against MCF7, HeLa and PC3 cancer cell lines and 3T3 normal fibroblast cell line did not show cytotoxicity at 30 muM.

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