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MK-2894 sodium salt

EP4 antagonist CAS# 1006036-88-9

MK-2894 sodium salt

Catalog No. BCC1758----Order now to get a substantial discount!

Product Name & Size Price Stock
MK-2894 sodium salt: 5mg $196 In Stock
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Quality Control of MK-2894 sodium salt

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Chemical structure

MK-2894 sodium salt

3D structure

Chemical Properties of MK-2894 sodium salt

Cas No. 1006036-88-9 SDF Download SDF
PubChem ID 24953972 Appearance Powder
Formula C25H21F3NNaO3S M.Wt 495.49
Type of Compound N/A Storage Desiccate at -20°C
Solubility DMSO
Chemical Name sodium;4-[1-[[2,5-dimethyl-4-[[4-(trifluoromethyl)phenyl]methyl]thiophene-3-carbonyl]amino]cyclopropyl]benzoate
SMILES CC1=C(C(=C(S1)C)C(=O)NC2(CC2)C3=CC=C(C=C3)C(=O)[O-])CC4=CC=C(C=C4)C(F)(F)F.[Na+]
Standard InChIKey RQRUUNKVGDVBFV-UHFFFAOYSA-M
Standard InChI InChI=1S/C25H22F3NO3S.Na/c1-14-20(13-16-3-7-19(8-4-16)25(26,27)28)21(15(2)33-14)22(30)29-24(11-12-24)18-9-5-17(6-10-18)23(31)32;/h3-10H,11-13H2,1-2H3,(H,29,30)(H,31,32);/q;+1/p-1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

MK-2894 sodium salt Dilution Calculator

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MK-2894 sodium salt Molarity Calculator

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Preparing Stock Solutions of MK-2894 sodium salt

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.0182 mL 10.091 mL 20.182 mL 40.3641 mL 50.4551 mL
5 mM 0.4036 mL 2.0182 mL 4.0364 mL 8.0728 mL 10.091 mL
10 mM 0.2018 mL 1.0091 mL 2.0182 mL 4.0364 mL 5.0455 mL
50 mM 0.0404 mL 0.2018 mL 0.4036 mL 0.8073 mL 1.0091 mL
100 mM 0.0202 mL 0.1009 mL 0.2018 mL 0.4036 mL 0.5046 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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Background on MK-2894 sodium salt

MK-2894, a highly potent and selective second generation EP4 antagonist.MK-2894 exhibits favorable pharmacokinetic profile in a number of preclinical species and potent anti-inflammatory activity in several animal models of pain/inflammation. MK-2894 also shows favorable GI tolerability profile in rats when compared to traditional NSAID indomethacin.

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Description

MK-2894 sodium salt is a highly potent and selective second generation EP4 antagonist.

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