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Monnieriside G

CAS# 1401799-34-5

Monnieriside G

2D Structure

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Monnieriside G

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Chemical Properties of Monnieriside G

Cas No. 1401799-34-5 SDF Download SDF
PubChem ID 124510520 Appearance Powder
Formula C21H26O10 M.Wt 438.43
Type of Compound Phenols Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (2R)-4-hydroxy-7-methyl-2-[2-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxypropan-2-yl]-2,3-dihydrofuro[3,2-g]chromen-5-one
SMILES CC1=CC(=O)C2=C(C3=C(C=C2O1)OC(C3)C(C)(C)OC4C(C(C(C(O4)CO)O)O)O)O
Standard InChIKey KHWKLNXMSVVKCH-BQLFOJHWSA-N
Standard InChI InChI=1S/C21H26O10/c1-8-4-10(23)15-12(28-8)6-11-9(16(15)24)5-14(29-11)21(2,3)31-20-19(27)18(26)17(25)13(7-22)30-20/h4,6,13-14,17-20,22,24-27H,5,7H2,1-3H3/t13-,14-,17-,18+,19-,20+/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Monnieriside G

The fruits of Cnidium monnieri.

Biological Activity of Monnieriside G

DescriptionMonnieriside G is a natural product from Cnidium monnieri.

Protocol of Monnieriside G

Structure Identification
Planta Medica, 2012, 78(11):1204-1204.

New cromones from Cnidium monnieri fruits inhibit adipocyte differentiation in 3T3-L1 cells.[Reference: WebLink]


METHODS AND RESULTS:
Seven new chromone glycosides, monnieriside A (3),monnieriside B (10), monnieriside C (12) monnieriside D (13), monnieriside E (15), monnieriside F (16), Monnieriside G (17) and one new phenolic compound, methylpicraquassioside B (23) were isolated from the n-BuOH soluble fraction of Cnidium monnieri fruits (Umbelliferae), together with fourteen known compounds, undulatoside A (1), cnidimol C (2), saikochromoside A (4), cnidimoside A (5), cnidimoside B (6), 2-methyl-5-hydroxy-6-(2-butenyl-3-hydroxymethyl)-7-(β-D-glucopyranosyloxy)-4H-1-benzopyran-4-one (7), cnidimol D (8), hydroxycnidimoside A (9), umtatin (11), 6′-hydroxylangelicain (14), cnidioside A (18), cnidioside B (19), picraquassioside A (20), methylpicraquassioside A (21) and picraquassioside B (22). The structures of isolated compounds were determined on the basis of spectroscopic analysis including 1D, 2D NMR and HRESI-MS.
CONCLUSIONS:
Among the compounds isolated, compounds 5, 6, 9 and 10 significantly inhibited adipocyte differentiation as measured by fat accumulation in 3T3-L1 cells using Oil Red O staining.

Monnieriside G Dilution Calculator

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Preparing Stock Solutions of Monnieriside G

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.2809 mL 11.4043 mL 22.8087 mL 45.6173 mL 57.0216 mL
5 mM 0.4562 mL 2.2809 mL 4.5617 mL 9.1235 mL 11.4043 mL
10 mM 0.2281 mL 1.1404 mL 2.2809 mL 4.5617 mL 5.7022 mL
50 mM 0.0456 mL 0.2281 mL 0.4562 mL 0.9123 mL 1.1404 mL
100 mM 0.0228 mL 0.114 mL 0.2281 mL 0.4562 mL 0.5702 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Monnieriside G

New cromones from Cnidium monnieri fruits inhibit adipocyte differentiation in 3T3-L1 cells.

Planta Medica, 2012, 78(11):1204-1204.

Seven new chromone glycosides, monnieriside A (3),monnieriside B (10), monnieriside C (12) monnieriside D (13), monnieriside E (15), monnieriside F (16), Monnieriside G (17) and one new phenolic compound, methylpicraquassioside B (23) were isolated from the n-BuOH soluble fraction of Cnidium monnieri fruits (Umbelliferae), together with fourteen known compounds, undulatoside A (1), cnidimol C (2), saikochromoside A (4), cnidimoside A (5), cnidimoside B (6), 2-methyl-5-hydroxy-6-(2-butenyl-3-hydroxymethyl)-7-(β-D-glucopyranosyloxy)-4H-1-benzopyran-4-one (7), cnidimol D (8), hydroxycnidimoside A (9), umtatin (11), 6′-hydroxylangelicain (14), cnidioside A (18), cnidioside B (19), picraquassioside A (20), methylpicraquassioside A (21) and picraquassioside B (22). The structures of isolated compounds were determined on the basis of spectroscopic analysis including 1D, 2D NMR and HRESI-MS. Among the compounds isolated, compounds 5, 6, 9 and 10 significantly inhibited adipocyte differentiation as measured by fat accumulation in 3T3-L1 cells using Oil Red O staining.

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