Monnieriside A

CAS# 1401807-73-5

Monnieriside A

Catalog No. BCN7892----Order now to get a substantial discount!

Product Name & Size Price Stock
Monnieriside A: 5mg Please Inquire In Stock
Monnieriside A: 10mg Please Inquire In Stock
Monnieriside A: 20mg Please Inquire Please Inquire
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Quality Control of Monnieriside A

Number of papers citing our products

Chemical structure

Monnieriside A

3D structure

Chemical Properties of Monnieriside A

Cas No. 1401807-73-5 SDF Download SDF
PubChem ID 70686986 Appearance Powder
Formula C16H18O10 M.Wt 370.31
Type of Compound Flavonoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 5,7-dihydroxy-2-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]chromen-4-one
SMILES C1=C(C=C2C(=C1O)C(=O)C=C(O2)COC3C(C(C(C(O3)CO)O)O)O)O
Standard InChIKey HKSWNVKSXBFJGZ-YMILTQATSA-N
Standard InChI InChI=1S/C16H18O10/c17-4-11-13(21)14(22)15(23)16(26-11)24-5-7-3-9(20)12-8(19)1-6(18)2-10(12)25-7/h1-3,11,13-19,21-23H,4-5H2/t11-,13-,14+,15-,16-/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Monnieriside A

The herbs of Drynaria fortunei

Biological Activity of Monnieriside A

DescriptionMonnieriside A is a natural product from Drynaria fortunei.
In vitro

Anti-adipogenic chromone glycosides from Cnidium monnieri fruits in 3T3-L1 cells.[Pubmed: 22932311]

Bioorg Med Chem Lett. 2012 Oct 1;22(19):6267-71.


METHODS AND RESULTS:
Seven new chromone glycosides, Monnieriside A (3),monnieriside B (10),monnieriside C (11), monnieriside D (12), monnieriside E (13), monnieriside F (15) and monnieriside G (16) were isolated from Cnidium. monnieri, together with ten known chromone derivatives, undulatoside A (1), cnidimol C (2), saikochromoside A (4), cnidimoside A (5), cnidimoside B (6), 2-methyl-5-hydroxy-6-(2-butenyl-3-hydroxymethyl)-7-(β-d-glucopyranosyloxy)-4H-1-benzopyran-4-one (7), cnidimol D (8), hydroxycnidimoside A (9), umtatin (14) and 6'-hydroxylangelicain (17). The structures of isolated compounds were determined on the basis of spectroscopic analysis including 1D, 2D NMR and HR-MS.
CONCLUSIONS:
Among the compounds isolated, compounds 5, 6, 9 and 10 significantly inhibited adipocyte differentiation as measured by fat accumulation in 3T3-L1 cells using Oil Red O staining.

Monnieriside A Dilution Calculator

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Monnieriside A Molarity Calculator

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Preparing Stock Solutions of Monnieriside A

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.7004 mL 13.5022 mL 27.0044 mL 54.0088 mL 67.511 mL
5 mM 0.5401 mL 2.7004 mL 5.4009 mL 10.8018 mL 13.5022 mL
10 mM 0.27 mL 1.3502 mL 2.7004 mL 5.4009 mL 6.7511 mL
50 mM 0.054 mL 0.27 mL 0.5401 mL 1.0802 mL 1.3502 mL
100 mM 0.027 mL 0.135 mL 0.27 mL 0.5401 mL 0.6751 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Monnieriside A

Anti-adipogenic chromone glycosides from Cnidium monnieri fruits in 3T3-L1 cells.[Pubmed:22932311]

Bioorg Med Chem Lett. 2012 Oct 1;22(19):6267-71.

Seven new chromone glycosides, monnierisides A (3), B (10), C (11), D (12), E (13), F (15) and G (16) were isolated from Cnidium. monnieri, together with ten known chromone derivatives, undulatoside A (1), cnidimol C (2), saikochromoside A (4), cnidimoside A (5), cnidimoside B (6), 2-methyl-5-hydroxy-6-(2-butenyl-3-hydroxymethyl)-7-(beta-d-glucopyranosyloxy)-4H- 1-benzopyran-4-one (7), cnidimol D (8), hydroxycnidimoside A (9), umtatin (14) and 6'-hydroxylangelicain (17). The structures of isolated compounds were determined on the basis of spectroscopic analysis including 1D, 2D NMR and HR-MS. Among the compounds isolated, compounds 5, 6, 9 and 10 significantly inhibited adipocyte differentiation as measured by fat accumulation in 3T3-L1 cells using Oil Red O staining.

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