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Monocrotaline N-oxide

CAS# 35337-98-5

Monocrotaline N-oxide

Catalog No. BCN2097----Order now to get a substantial discount!

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Quality Control of Monocrotaline N-oxide

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Chemical structure

Monocrotaline N-oxide

3D structure

Chemical Properties of Monocrotaline N-oxide

Cas No. 35337-98-5 SDF Download SDF
PubChem ID 197173 Appearance White-brownish powder
Formula C16H23NO7 M.Wt 341.36
Type of Compound Alkaloids Storage Desiccate at -20°C
Solubility Soluble in methan
SMILES CC1C(=O)OC2CC[N+]3(C2C(=CC3)COC(=O)C(C1(C)O)(C)O)[O-]
Standard InChIKey LHVAZUAALQTANZ-UHFFFAOYSA-N
Standard InChI InChI=1S/C16H23NO7/c1-9-13(18)24-11-5-7-17(22)6-4-10(12(11)17)8-23-14(19)16(3,21)15(9,2)20/h4,9,11-12,20-21H,5-8H2,1-3H3
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Monocrotaline N-oxide

The herbs of Crotalaria pallida Ait.

Biological Activity of Monocrotaline N-oxide

Description1. Monocrotaline N-oxide is a phagostimulant for larvae and it stimulates the growth and development of adult male androconial organs called coremata. 2. Monocrotaline N-oxide fed to larvae also affects the courtship behavior of adult males. 3. Monocrotaline N-oxide is an adequate precursor for the production of the courtship pheromone hydroxydanaidal.

Monocrotaline N-oxide Dilution Calculator

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Monocrotaline N-oxide Molarity Calculator

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Preparing Stock Solutions of Monocrotaline N-oxide

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.9295 mL 14.6473 mL 29.2946 mL 58.5892 mL 73.2365 mL
5 mM 0.5859 mL 2.9295 mL 5.8589 mL 11.7178 mL 14.6473 mL
10 mM 0.2929 mL 1.4647 mL 2.9295 mL 5.8589 mL 7.3236 mL
50 mM 0.0586 mL 0.2929 mL 0.5859 mL 1.1718 mL 1.4647 mL
100 mM 0.0293 mL 0.1465 mL 0.2929 mL 0.5859 mL 0.7324 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Monocrotaline N-oxide

If you've got it, flaunt it: ingested alkaloids affect corematal display behavior in the salt marsh moth, Estigmene acrea.[Pubmed:16299591]

J Insect Sci. 2005;5:1.

Plant-derived pyrrolizidine alkaloids play an important role in the biology of the salt marsh moth, Estigmene acrea (Lepidoptera: Arctiidae). They are phagostimulants for larvae and they stimulate the growth and development of adult male androconial organs called coremata. In this study, we have shown that the pyrrolizidine alkaloid Monocrotaline N-oxide (MNO) fed to larvae also affects the courtship behavior of adult males. Males fed a diet containing MNO display their coremata while males fed on the same diet without alkaloid rarely display. This explains why it has been difficult to replicate field observations of the "lekking" behavior of this species in the laboratory where animals are frequently raised on commercially available diets devoid of alkaloids. Corematal inflation was observed in isolated males and in laboratory leks. The effect of larvae feeding on pyrrolizidine alkaloid on the reproductive behavior of adults suggests that this substance may modify the development of the moth's nervous system and contribute to their unusual dual mating strategies. MNO was also shown to be an adequate precursor for the production of the courtship pheromone hydroxydanaidal.

Description

Monocrotaline N-Oxide, a monocrotaline metabolite, leads to DNA adduct formation in vivo.

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