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Mulberroside C

CAS# 102841-43-0

Mulberroside C

Catalog No. BCN6344----Order now to get a substantial discount!

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Mulberroside C: 5mg $69 In Stock
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Quality Control of Mulberroside C

Number of papers citing our products

Chemical structure

Mulberroside C

3D structure

Chemical Properties of Mulberroside C

Cas No. 102841-43-0 SDF Download SDF
PubChem ID 190453 Appearance Powder
Formula C24H26O9 M.Wt 458.46
Type of Compound Phenols Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (2S,3R,4S,5R)-2-[3-hydroxy-5-(6-hydroxy-7,7-dimethyl-5,6-dihydrofuro[3,2-g]chromen-2-yl)phenoxy]oxane-3,4,5-triol
SMILES CC1(C(CC2=C(O1)C=C3C(=C2)C=C(O3)C4=CC(=CC(=C4)OC5C(C(C(CO5)O)O)O)O)O)C
Standard InChIKey OHVJCFZJKPEJRL-BOWLQXBNSA-N
Standard InChI InChI=1S/C24H26O9/c1-24(2)20(27)7-12-3-11-6-17(32-18(11)9-19(12)33-24)13-4-14(25)8-15(5-13)31-23-22(29)21(28)16(26)10-30-23/h3-6,8-9,16,20-23,25-29H,7,10H2,1-2H3/t16-,20?,21+,22-,23+/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Mulberroside C

The root bark of Morus alba L.

Biological Activity of Mulberroside C

DescriptionMulberroside C shows weak activity (IC 50 =75.4 μg/ml) against herpes simplex type 1 virus (HSV-1).
TargetsHSV
In vitro

[2-Arylbenzofuran derivatives from Morus wittiorum].[Pubmed: 19239031]

Yao Xue Xue Bao. 2008 Nov;43(11):1119-22.

The investigation on the stem bark of Morus wittiorum was carried out to find its chemical constituents possessing anti-oxidative activity.
METHODS AND RESULTS:
The isolation and purification were performed by various chromatographies such as silica gel, Sephadex LH-20, RP-C18 column chromatography and so on. Based on the spectral analysis such as NMR, MS, etc., seven 2-arylbenzofuran derivatives were identified as wittifuran D (1), wittifuran E (2), moracin C (3), moracin M (4), moracin P (5), 2-(3,5-dihydroxyphenyl)-5,6-dihydroxybenzofuran (6) and Mulberroside C (7). Compounds 1-7 were isolated from this plant for the first time. Among them, 1 and 2 were new compounds. Compounds 3-7 were used to assay antioxidant activity, the inhibitory ratios of compounds 3, 4, 6, at a concentration of 1 x 10(-5) mol x L(-1), to malondialdehyde (MDA) produced during microsomal lipid peroxidation induced by ferrous-cysteine were 73%, 69% and 89% respectively.

Antiviral flavonoids from the root bark of Morus alba L.[Pubmed: 12648543]

Phytochemistry. 2003 Apr;62(8):1235-8.


METHODS AND RESULTS:
A prenylated flavonoid, moralbanone, along with seven known compounds kuwanon S, Mulberroside C, cyclomorusin, eudraflavone B hydroperoxide, oxydihydromorusin, leachianone G and alpha-acetyl-amyrin were isolated from the root bark of Morus alba L. Leachianone G showed potent antiviral activity (IC(50) = 1.6 microg/ml), whereas Mulberroside C showed weak activity (IC(50) = 75.4 microg/ml) against herpes simplex type 1 virus (HSV-1).
CONCLUSIONS:
Their structures were elucidated by spectroscopic methods.

Protocol of Mulberroside C

Structure Identification
Zhongguo Zhong Yao Za Zhi. 2010 Aug;35(15):1978-82.

[Chemical constituents from root barks of Morus atropurpurea].[Pubmed: 20931850]

To study the chemical constituents from the root barks of Morus atropurpurea.
METHODS AND RESULTS:
The chemical constituents from the 70% ethanol extract of M. atropurpurea were isolated and purified by column chromatographic methods. Their structures were identified by physico-chemical properties as well as spectral data. RESULT: Fifteen compounds were isolated and identified as sanggenol O(1), kuwanon S(2), moracin C(3), mulberrofuran A(4), mulberrofuran B(5), mulberrofuran C(6), mulberrofuran G(7), mulberroside A(8), Mulberroside C(9), 1-deoxynojirimycin(10), 2-O-alpha-D-galactopyranosyl-1-deoxynojirimycin(11), fagomine(12), betulinic acid(13), ursolic acid(14) and beta-sitosterol(15).
CONCLUSIONS:
Compounds 1-6 and 8-13 were isolated from M. atropurpurea for the first time.

Mulberroside C Dilution Calculator

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Mulberroside C Molarity Calculator

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Preparing Stock Solutions of Mulberroside C

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.1812 mL 10.9061 mL 21.8122 mL 43.6243 mL 54.5304 mL
5 mM 0.4362 mL 2.1812 mL 4.3624 mL 8.7249 mL 10.9061 mL
10 mM 0.2181 mL 1.0906 mL 2.1812 mL 4.3624 mL 5.453 mL
50 mM 0.0436 mL 0.2181 mL 0.4362 mL 0.8725 mL 1.0906 mL
100 mM 0.0218 mL 0.1091 mL 0.2181 mL 0.4362 mL 0.5453 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Mulberroside C

[2-Arylbenzofuran derivatives from Morus wittiorum].[Pubmed:19239031]

Yao Xue Xue Bao. 2008 Nov;43(11):1119-22.

The investigation on the stem bark of Morus wittiorum was carried out to find its chemical constituents possessing anti-oxidative activity. The isolation and purification were performed by various chromatographies such as silica gel, Sephadex LH-20, RP-C18 column chromatography and so on. Based on the spectral analysis such as NMR, MS, etc., seven 2-arylbenzofuran derivatives were identified as wittifuran D (1), wittifuran E (2), moracin C (3), moracin M (4), moracin P (5), 2-(3,5-dihydroxyphenyl)-5,6-dihydroxybenzofuran (6) and Mulberroside C (7). Compounds 1-7 were isolated from this plant for the first time. Among them, 1 and 2 were new compounds. Compounds 3-7 were used to assay antioxidant activity, the inhibitory ratios of compounds 3, 4, 6, at a concentration of 1 x 10(-5) mol x L(-1), to malondialdehyde (MDA) produced during microsomal lipid peroxidation induced by ferrous-cysteine were 73%, 69% and 89% respectively.

Antiviral flavonoids from the root bark of Morus alba L.[Pubmed:12648543]

Phytochemistry. 2003 Apr;62(8):1235-8.

A prenylated flavonoid, moralbanone, along with seven known compounds kuwanon S, Mulberroside C, cyclomorusin, eudraflavone B hydroperoxide, oxydihydromorusin, leachianone G and alpha-acetyl-amyrin were isolated from the root bark of Morus alba L. Leachianone G showed potent antiviral activity (IC(50) = 1.6 microg/ml), whereas Mulberroside C showed weak activity (IC(50) = 75.4 microg/ml) against herpes simplex type 1 virus (HSV-1). Their structures were elucidated by spectroscopic methods.

[Chemical constituents from root barks of Morus atropurpurea].[Pubmed:20931850]

Zhongguo Zhong Yao Za Zhi. 2010 Aug;35(15):1978-82.

OBJECTIVE: To study the chemical constituents from the root barks of Morus atropurpurea. METHOD: The chemical constituents from the 70% ethanol extract of M. atropurpurea were isolated and purified by column chromatographic methods. Their structures were identified by physico-chemical properties as well as spectral data. RESULT: Fifteen compounds were isolated and identified as sanggenol O(1), kuwanon S(2), moracin C(3), mulberrofuran A(4), mulberrofuran B(5), mulberrofuran C(6), mulberrofuran G(7), mulberroside A(8), Mulberroside C(9), 1-deoxynojirimycin(10), 2-O-alpha-D-galactopyranosyl-1-deoxynojirimycin(11), fagomine(12), betulinic acid(13), ursolic acid(14) and beta-sitosterol(15). CONCLUSION: Compounds 1-6 and 8-13 were isolated from M. atropurpurea for the first time.

Description

Mulberroside C is one of the main bioactive constituents in mulberry (Morus alba L.). Mulberroside C is a HCV replicon inhibitor. Antiviral activity.

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