Myriceric acid C

CAS# 162059-94-1

Myriceric acid C

Catalog No. BCN1719----Order now to get a substantial discount!

Product Name & Size Price Stock
Myriceric acid C: 5mg Please Inquire In Stock
Myriceric acid C: 10mg Please Inquire In Stock
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Quality Control of Myriceric acid C

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Chemical structure

Myriceric acid C

3D structure

Chemical Properties of Myriceric acid C

Cas No. 162059-94-1 SDF Download SDF
PubChem ID 15767725 Appearance Powder
Formula C48H60O10 M.Wt 797.0
Type of Compound Triterpenoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (4aS,6aR,6aR,6bR,8aR,10S,12aR,14bS)-10-[(E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy-6a-[[(E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxymethyl]-2,2,6b,9,9,12a-hexamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid
SMILES CC1(CCC2(CCC3(C(=CCC4C3(CCC5C4(CCC(C5(C)C)OC(=O)C=CC6=CC(=C(C=C6)O)O)C)C)C2C1)COC(=O)C=CC7=CC(=C(C=C7)O)O)C(=O)O)C
Standard InChIKey OQOHHYHCCUJBHE-HQEPTUIISA-N
Standard InChI InChI=1S/C48H60O10/c1-43(2)21-22-47(42(55)56)23-24-48(28-57-40(53)15-9-29-7-12-33(49)35(51)25-29)31(32(47)27-43)11-14-38-45(5)19-18-39(44(3,4)37(45)17-20-46(38,48)6)58-41(54)16-10-30-8-13-34(50)36(52)26-30/h7-13,15-16,25-26,32,37-39,49-52H,14,17-24,27-28H2,1-6H3,(H,55,56)/b15-9+,16-10+/t32-,37-,38+,39-,45-,46+,47-,48-/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Myriceric acid C

The herbs of Myrica cerifera

Biological Activity of Myriceric acid C

Description1. Myriceric acid C has cytotoxic activity against human lung carcinoma and breast carcinoma.
TargetsEndothelin Receptor

Myriceric acid C Dilution Calculator

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Myriceric acid C Molarity Calculator

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Preparing Stock Solutions of Myriceric acid C

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.2547 mL 6.2735 mL 12.5471 mL 25.0941 mL 31.3676 mL
5 mM 0.2509 mL 1.2547 mL 2.5094 mL 5.0188 mL 6.2735 mL
10 mM 0.1255 mL 0.6274 mL 1.2547 mL 2.5094 mL 3.1368 mL
50 mM 0.0251 mL 0.1255 mL 0.2509 mL 0.5019 mL 0.6274 mL
100 mM 0.0125 mL 0.0627 mL 0.1255 mL 0.2509 mL 0.3137 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Myriceric acid C

Endothelin receptor antagonist triterpenoid, myriceric acid A, isolated from Myrica cerifera, and structure activity relationships of its derivatives.[Pubmed:8998841]

Chem Pharm Bull (Tokyo). 1996 Feb;44(2):343-51.

As the first non-peptide endothelin receptor antagonist from a higher plant, a new triterpenoid, myriceric acid A (50-235) (1) was isolated from the bayberry, Myrica cerifera. Myriceric acid A (1) inhibited not only an endothelin-1-induced increase in cytosolic free Ca2+ concentration (IC50 = 11 +/- 2 nM) but [125I]endothelin-1 binding in rat aortic smooth muscle cells (Ki = 66 +/- 15 nM). Two new related triterpenoids, Myriceric acid C (6), and myriceric acid D (8), were also isolated. Furthermore, the chemical modification of these natural products led to the synthesis of sulfated derivatives (13, 14, 15) which showed 1.5 to 20 times higher affinity for endothelin receptors. The structure activity relationships of myriceric acids and their derivatives are discussed.

Constituents from the stems of Hibiscus taiwanensis.[Pubmed:15635230]

Chem Pharm Bull (Tokyo). 2005 Jan;53(1):56-9.

Five new compounds, hibicuslide A (1), hibicuslide B (2), hibicuslide C (3), hibicutaiwanin (4), hibicusin (5), and fifty-one known compounds have been isolated from the stems of Hibiscus taiwanensis. The structures of these compounds were determined by spectroscopic and chemical transformation methods. Among them, mansonone H (19) and uncarinic acid A (30) inhibited HIV replication in H9 lymphocyte cells. The 9,9'-O-feruloyl-(-)-secoisolaricinresinol (12), Myriceric acid C (29), and uncarinic acid A (30) showed cytotoxic activity against human lung carcinoma and breast carcinoma.

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