Home >> Research Area >>Natural Products>>Alkaloids>> N1-Phenylsuberamide

N1-Phenylsuberamide

CAS# 1305124-48-4

N1-Phenylsuberamide

Catalog No. BCX0407----Order now to get a substantial discount!

Product Name & Size Price Stock
N1-Phenylsuberamide: 5mg $552 In Stock
N1-Phenylsuberamide: 10mg Please Inquire In Stock
N1-Phenylsuberamide: 20mg Please Inquire Please Inquire
N1-Phenylsuberamide: 50mg Please Inquire Please Inquire
N1-Phenylsuberamide: 100mg Please Inquire Please Inquire
N1-Phenylsuberamide: 200mg Please Inquire Please Inquire
N1-Phenylsuberamide: 500mg Please Inquire Please Inquire
N1-Phenylsuberamide: 1000mg Please Inquire Please Inquire

Quality Control of N1-Phenylsuberamide

Number of papers citing our products

Chemical structure

N1-Phenylsuberamide

3D structure

Chemical Properties of N1-Phenylsuberamide

Cas No. 1305124-48-4 SDF Download SDF
PubChem ID 23075284 Appearance Powder
Formula C14H20N2O2 M.Wt 248.32
Type of Compound Alkaloids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name N'-phenyloctanediamide
SMILES C1=CC=C(C=C1)NC(=O)CCCCCCC(=O)N
Standard InChIKey FYALHEGRKUJDBE-UHFFFAOYSA-N
Standard InChI InChI=1S/C14H20N2O2/c15-13(17)10-6-1-2-7-11-14(18)16-12-8-4-3-5-9-12/h3-5,8-9H,1-2,6-7,10-11H2,(H2,15,17)(H,16,18)
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

N1-Phenylsuberamide Dilution Calculator

Concentration (start)
x
Volume (start)
=
Concentration (final)
x
Volume (final)
 
 
 
C1
V1
C2
V2

calculate

N1-Phenylsuberamide Molarity Calculator

Mass
=
Concentration
x
Volume
x
MW*
 
 
 
g/mol

calculate

Preparing Stock Solutions of N1-Phenylsuberamide

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 4.0271 mL 20.1353 mL 40.2706 mL 80.5412 mL 100.6765 mL
5 mM 0.8054 mL 4.0271 mL 8.0541 mL 16.1082 mL 20.1353 mL
10 mM 0.4027 mL 2.0135 mL 4.0271 mL 8.0541 mL 10.0677 mL
50 mM 0.0805 mL 0.4027 mL 0.8054 mL 1.6108 mL 2.0135 mL
100 mM 0.0403 mL 0.2014 mL 0.4027 mL 0.8054 mL 1.0068 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

Organizitions Citing Our Products recently

 
 
 

Calcutta University

University of Minnesota

University of Maryland School of Medicine

University of Illinois at Chicago

The Ohio State University

University of Zurich

Harvard University

Colorado State University

Auburn University

Yale University

Worcester Polytechnic Institute

Washington State University

Stanford University

University of Leipzig

Universidade da Beira Interior

The Institute of Cancer Research

Heidelberg University

University of Amsterdam

University of Auckland
TsingHua University
TsingHua University
The University of Michigan
The University of Michigan
Miami University
Miami University
DRURY University
DRURY University
Jilin University
Jilin University
Fudan University
Fudan University
Wuhan University
Wuhan University
Sun Yat-sen University
Sun Yat-sen University
Universite de Paris
Universite de Paris
Deemed University
Deemed University
Auckland University
Auckland University
The University of Tokyo
The University of Tokyo
Korea University
Korea University
Featured Products
New Products
 

References on N1-Phenylsuberamide

Efficient new constructs against triple negative breast cancer cells: synthesis and preliminary biological study of ferrocifen-SAHA hybrids and related species.[Pubmed:24030275]

Dalton Trans. 2013 Nov 21;42(43):15489-501.

Chemotherapeutic agents combining several active groups within a single molecule can modulate multiple cellular pathways and, thus, exhibit higher efficacy than single-target drugs. In this study, six new hybrid compounds combining tamoxifen (TAM) or ferrocifen (FcTAM) structural motifs with suberoylanilide hydroxamic acid (SAHA) were synthesised and evaluated. Antiproliferative activity was first explored in cancer cell lines. Combining FcTAM and SAHA structural motifs to form the unprecedented FcTAM-SAHA hybrid molecule led to an increased cytotoxicity (IC50 = 0.7 muM) in triple-negative MDA-MB-231 breast cancer cells when compared to FcTAM or SAHA alone (IC50 = 2.6 muM and 3.6 muM, respectively), while the organic hybrid analogue TAM-SAHA was far less cytotoxic (IC50 = 8.6 muM). In hormone-dependent MCF-7 breast cancer cells, FcTAM-SAHA was more active (IC50 = 2.0 muM) than FcTAM (IC50 = 4.4 muM) and TAM-SAHA (IC50 > 10 muM), but less toxic than SAHA (IC50 = 1.0 muM). Surprisingly, FcTAM-PSA, an N1-Phenylsuberamide derivative, also possessed strong antiproliferative activity (IC50 = 0.5 muM and 1.8 muM in MDA-MB-231 and MCF-7 cells, respectively). Subsequent biochemical studies indicate that estrogen receptor alpha (ERalpha) and histone deacetylases (HDAC) are not the main targets of the hybrid compounds for their antiproliferative effect. Interestingly, both organometallic compounds were able to induce p21waf1/cip1 gene expression in MCF-7 breast cancer cells in accordance with their antiproliferative activity.

Keywords:

N1-Phenylsuberamide,1305124-48-4,Natural Products, buy N1-Phenylsuberamide , N1-Phenylsuberamide supplier , purchase N1-Phenylsuberamide , N1-Phenylsuberamide cost , N1-Phenylsuberamide manufacturer , order N1-Phenylsuberamide , high purity N1-Phenylsuberamide

Online Inquiry for:

      Fill out the information below

      • Size:Qty: - +

      * Required Fields

                                      Result: