Neopuerarin ACAS# 1150314-34-3 |
- Neopuerarin B
Catalog No.:BCX0997
CAS No.:1150314-39-8
Quality Control & MSDS
3D structure
Package In Stock
Number of papers citing our products
| Cas No. | 1150314-34-3 | SDF | Download SDF |
| PubChem ID | 91173115.0 | Appearance | Powder |
| Formula | C21H20O9 | M.Wt | 416.38 |
| Type of Compound | Flavonoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | 8-[(2R,3R,4R,5R)-5-[(1R)-1,2-dihydroxyethyl]-3,4-dihydroxyoxolan-2-yl]-7-hydroxy-3-(4-hydroxyphenyl)chromen-4-one | ||
| SMILES | C1=CC(=CC=C1C2=COC3=C(C2=O)C=CC(=C3C4C(C(C(O4)C(CO)O)O)O)O)O | ||
| Standard InChIKey | ANUVQPJCPQLESC-OMFXLVFUSA-N | ||
| Standard InChI | InChI=1S/C21H20O9/c22-7-14(25)20-17(27)18(28)21(30-20)15-13(24)6-5-11-16(26)12(8-29-19(11)15)9-1-3-10(23)4-2-9/h1-6,8,14,17-18,20-25,27-28H,7H2/t14-,17-,18-,20-,21-/m1/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
||
| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
||
| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
Neopuerarin A Dilution Calculator
Neopuerarin A Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.4017 mL | 12.0083 mL | 24.0165 mL | 48.033 mL | 60.0413 mL |
| 5 mM | 0.4803 mL | 2.4017 mL | 4.8033 mL | 9.6066 mL | 12.0083 mL |
| 10 mM | 0.2402 mL | 1.2008 mL | 2.4017 mL | 4.8033 mL | 6.0041 mL |
| 50 mM | 0.048 mL | 0.2402 mL | 0.4803 mL | 0.9607 mL | 1.2008 mL |
| 100 mM | 0.024 mL | 0.1201 mL | 0.2402 mL | 0.4803 mL | 0.6004 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
Calcutta University
University of Minnesota
University of Maryland School of Medicine
University of Illinois at Chicago
The Ohio State University
University of Zurich
Harvard University
Colorado State University
Auburn University
Yale University
Worcester Polytechnic Institute
Washington State University
Stanford University
University of Leipzig
Universidade da Beira Interior
The Institute of Cancer Research
Heidelberg University
University of Amsterdam
University of Auckland
TsingHua University
The University of Michigan
Miami University
DRURY University
Jilin University
Fudan University
Wuhan University
Sun Yat-sen University
Universite de Paris
Deemed University
Auckland University
The University of Tokyo
Korea University
- Zeatin
Catalog No.:BCX1016
CAS No.:13114-27-7
- 6,8-Dihydroxy-1,2,7-trimethoxy-3-methylanthraquinone
Catalog No.:BCX1015
CAS No.:1622982-59-5
- Cycloastragenol-6-O-β-D-glucoside
Catalog No.:BCX1014
CAS No.:86764-12-7
- 6'-Hydroxy-3,4,2',3',4'-pentamethoxychalcone
Catalog No.:BCX1013
CAS No.:114021-62-4
- Isomaltotetraose
Catalog No.:BCX1012
CAS No.:35997-20-7
- Isomaltopentaose
Catalog No.:BCX1011
CAS No.:6082-32-2
- Isomaltohexaose
Catalog No.:BCX1010
CAS No.:6175-02-6
- Isomaltoheptaose
Catalog No.:BCX1009
CAS No.:6513-12-8
- Isomaltooctaose
Catalog No.:BCX1008
CAS No.:35867-37-9
- Alitame hydrate
Catalog No.:BCX1007
CAS No.:99016-42-9
- Euphorbetin
Catalog No.:BCX1006
CAS No.:35897-99-5
- Hericene A
Catalog No.:BCX1005
CAS No.:157207-54-0
- Docosyl ferulate
Catalog No.:BCX1018
CAS No.:101927-24-6
- Furopelargone B
Catalog No.:BCX1019
CAS No.:1143-46-0
- Pseudostellarin A
Catalog No.:BCX1020
CAS No.:156430-20-5
- Soyasaponin Be
Catalog No.:BCX1021
CAS No.:117210-14-7
- Diphylloside A
Catalog No.:BCX1022
CAS No.:113558-11-5
- Pseudoginsenoside
Catalog No.:BCX1023
CAS No.:96158-07-5
- Notoginsenoside D
Catalog No.:BCX1024
CAS No.:193895-50-0
- Flavanone hydrazone
Catalog No.:BCX1025
CAS No.:1692-46-2
- Gallic acid 4-O-β-D-glucopyranoside
Catalog No.:BCX1026
CAS No.:84274-52-2
- 18α,20β-Glycyrrhizic acid
Catalog No.:BCX1027
CAS No.:83896-44-0
- 6-Hydroxymusizin 8-glucoside
Catalog No.:BCX1028
CAS No.:23566-96-3
- Ciwujianoside D2
Catalog No.:BCX1029
CAS No.:114892-57-8
New hepatoprotective isoflavone glucosides from Pueraria lobata (Willd.) Ohwi.[Pubmed:29968479]
Nat Prod Res. 2019 Dec;33(24):3485-3492.
Two new isoflavone glucosides, 3'-methoxyNeopuerarin A (1) and 3'-methoxyneopuerarin B (2), together with nine known isoflavones including puerarin (3), Neopuerarin A (4), neopuerarin B (5), daidzin (6), daidzein (7), 3'-methoxypuerarin (PG-3) (8), puerarin xyloside (9), mirificin (10), 3'-hydroxypuerarin (11) were isolated from the water extraction of the dried roots of Pueraria lobata (Willd.) Ohwi. Their structures were elucidated by the means of spectroscopic and chromatographic analysis methods. All compounds were evaluated for their hepatoprotective activity on HepG2 cells. All of them showed statistically significant hepatoprotective effect.
Isolation of two new C-glucofuranosyl isoflavones from Pueraria lobata (Wild.) Ohwi with HPLC-MS guiding analysis.[Pubmed:20419540]
J Asian Nat Prod Res. 2010 Apr;12(4):293-9.
A profiling analysis of the total isoflavone extract of the root of Pueraria lobata (Wild.) Ohwi was performed using HPLC coupled with ESI-ion trap mass spectrometry. A total of seven isoflavones were identified according to their retention times, UV, MS data, and comparing with the literature data. Among them, two proposed new compounds were isolated and their structures were determined to be 8-C-alpha-glucofuranosyl-7,4'-dihydroxyisoflavone and 8-C-beta-glucofuranosyl-7,4'-dihydroxyisoflavone, named as Neopuerarin A (7) and neopuerarin B (6), on the basis of chemical and spectral analyses.
Profiling and quantification of isoflavone-C-glycosides impurities in puerarin injection by liquid chromatography coupled to ESI-ion trap mass spectrometry.[Pubmed:19186018]
J Pharm Biomed Anal. 2009 Apr 5;49(3):843-7.
An HPLC/DAD/MS(n) method was established for the qualitative and quantitative analysis of the impurities in puerarin injection (PI), a widely used drug in China. The analytical HPLC was performed on an Agela RP-C18 column using 0.1% aqueous formic acid (v:v) and methanol as mobile phase. A total of nine impurities were detected and eight of them were identified as isoflavone-C-glycosides basing on their UV spectra and MS(n) spectra and comparing with the literature data. An HPLC method for the assay of two common impurities in the commercial PI samples, i.e., Neopuerarin A and neopuerarin B, was then established. The validation of the method, including sensitivity, linearity, precision, accuracy, was carried out. The calibration curves showed good linearity of R(2)>0.9999 and LOQ (S/N=10) were less than 3.73 ng. The precision was evaluated by intra- and inter-day assays and R.S.D. values were less than 0.94%. The average recovery rates were 97.0% and 99.5%, respectively, with R.S.D. less than 1.38%. The contents of Neopuerarin A and neopuerarin B in various commercial brands of PI samples varied over the range of 0.30-1.16% and 0.42-1.66%, respectively. This is the first report on the impurities in PI.
