(+)-NyasolCAS# 185020-38-6 |
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| Cas No. | 185020-38-6 | SDF | Download SDF |
| PubChem ID | 442880 | Appearance | Oil |
| Formula | C17H16O2 | M.Wt | 252.31 |
| Type of Compound | Lignans | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | 4-[(3S)-3-(4-hydroxyphenyl)penta-1,4-dienyl]phenol | ||
| SMILES | C=CC(C=CC1=CC=C(C=C1)O)C2=CC=C(C=C2)O | ||
| Standard InChIKey | VEAUNWQYYMXIRB-AWEZNQCLSA-N | ||
| Standard InChI | InChI=1S/C17H16O2/c1-2-14(15-7-11-17(19)12-8-15)6-3-13-4-9-16(18)10-5-13/h2-12,14,18-19H,1H2/t14-/m0/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
(+)-Nyasol Dilution Calculator
(+)-Nyasol Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 3.9634 mL | 19.8169 mL | 39.6338 mL | 79.2676 mL | 99.0845 mL |
| 5 mM | 0.7927 mL | 3.9634 mL | 7.9268 mL | 15.8535 mL | 19.8169 mL |
| 10 mM | 0.3963 mL | 1.9817 mL | 3.9634 mL | 7.9268 mL | 9.9084 mL |
| 50 mM | 0.0793 mL | 0.3963 mL | 0.7927 mL | 1.5854 mL | 1.9817 mL |
| 100 mM | 0.0396 mL | 0.1982 mL | 0.3963 mL | 0.7927 mL | 0.9908 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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[Alpha-glucosidase inhibitory active constituents contained in nutshell of Trapa acornis].[Pubmed:22860451]
Zhongguo Zhong Yao Za Zhi. 2012 May;37(10):1408-11.
OBJECTIVE: To study chemical constituents in nutshell of Trapa acornis and in vitro inhibitory activity against alpha-glucosidase. METHOD: EtOAC and n-butanol extractive fractions were separated by chromatography and their structures were identified by multiple spectroscopic techniques. RESULT: Nine compounds were separated, they were 4,23,24-trimethylcholest-22-en-3-ol (1), stigmasterol (2), alpha-amyrin (3), (+)-Nyasol (4), oleanolic acid (5), ursolic acid (6), hederagenin (7), 3,23-dihydroxy-12-ursen-28-oic acid (8) and beta-daucosterol (9). Total extracts from T. acornis nutshells, petroleum ether fractions, acetic ether fractions and normal butanol fractions showed inhibitory activity against alpha-glucosidase. Compound 5 (IC50 2.88 mg x L(-1)) and 6 (IC50 4.42 mg L(-1)) showed stronger inhibitory activity against alpha-glucosidase. CONCLUSION: All compounds except compound 2 were separated from the genus for the first time, and compound 1-9 were separated from this plant for the first time.
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