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Peroxydehydrotumulosic acid

CAS# 943225-53-4

Peroxydehydrotumulosic acid

Catalog No. BCN3739----Order now to get a substantial discount!

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Peroxydehydrotumulosic acid: 5mg Please Inquire In Stock
Peroxydehydrotumulosic acid: 10mg Please Inquire In Stock
Peroxydehydrotumulosic acid: 20mg Please Inquire Please Inquire
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Peroxydehydrotumulosic acid: 200mg Please Inquire Please Inquire
Peroxydehydrotumulosic acid: 500mg Please Inquire Please Inquire
Peroxydehydrotumulosic acid: 1000mg Please Inquire Please Inquire

Quality Control of Peroxydehydrotumulosic acid

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Chemical structure

Peroxydehydrotumulosic acid

3D structure

Chemical Properties of Peroxydehydrotumulosic acid

Cas No. 943225-53-4 SDF Download SDF
PubChem ID 102004606 Appearance Powder
Formula C31H46O6 M.Wt 514.7
Type of Compound Triterpenoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
SMILES CC(C)C(=C)CCC(C1C(CC2(C1(CC=C3C24C=CC5(C3(CCC(C5(C)C)O)C)OO4)C)C)O)C(=O)O
Standard InChIKey NWPSXIIQUKYLPR-BGOOFPDJSA-N
Standard InChI InChI=1S/C31H46O6/c1-18(2)19(3)9-10-20(25(34)35)24-21(32)17-29(8)28(24,7)13-11-22-27(6)14-12-23(33)26(4,5)31(27)16-15-30(22,29)36-37-31/h11,15-16,18,20-21,23-24,32-33H,3,9-10,12-14,17H2,1-2,4-8H3,(H,34,35)/t20-,21-,23+,24+,27-,28-,29-,30?,31?/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Peroxydehydrotumulosic acid

The root of Wolfiporia cocos (Schw.) Ryv.

Biological Activity of Peroxydehydrotumulosic acid

Description1. 5alpha,8alpha-Peroxydehydrotumulosic acid exhibits inhibitory effects against the Epstein-Barr virus early antigen (EBV-EA) activation induced by 12-O-tetradecanoylphorbol-13-acetate (TPA) in Raji cells.

Peroxydehydrotumulosic acid Dilution Calculator

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Peroxydehydrotumulosic acid Molarity Calculator

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Preparing Stock Solutions of Peroxydehydrotumulosic acid

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.9429 mL 9.7144 mL 19.4288 mL 38.8576 mL 48.572 mL
5 mM 0.3886 mL 1.9429 mL 3.8858 mL 7.7715 mL 9.7144 mL
10 mM 0.1943 mL 0.9714 mL 1.9429 mL 3.8858 mL 4.8572 mL
50 mM 0.0389 mL 0.1943 mL 0.3886 mL 0.7772 mL 0.9714 mL
100 mM 0.0194 mL 0.0971 mL 0.1943 mL 0.3886 mL 0.4857 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Peroxydehydrotumulosic acid

Triterpene acids from Poria cocos and their anti-tumor-promoting effects.[Pubmed:17488130]

J Nat Prod. 2007 Jun;70(6):948-53.

The structures of six new lanostane-type triterpene acids isolated from the epidermis of the sclerotia of Poria cocos were established to be 15alpha-hydroxydehydrotumulosic acid (5), 16alpha,25-dihydroxydehydroeburicoic acid (9), 5alpha,8alpha-Peroxydehydrotumulosic acid (10), 25-hydroxyporicoic acid H (11), 16-deoxyporicoic acid B (12), and poricoic acid CM (16) on the basis of spectroscopic methods. On evaluation of these six and 11 other known triterpene acids isolated from the sclerotium, 1-4, 6-8, 13-15, and 17, against the Epstein-Barr virus early antigen (EBV-EA) activation induced by 12-O-tetradecanoylphorbol-13-acetate (TPA) in Raji cells, all of the compounds except for 1, 3, 4, and 8 exhibited inhibitory effects with IC50 values of 195-340 mol ratio/32 pmol TPA. Compound 12 and poricoic acid C (13) exhibited inhibitory effects on skin tumor promotion in an in vivo two-stage carcinogenesis test using 7,12-dimethylbenz[a]anthracene (DMBA) as an initiator and TPA as a promoter.

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