Physalin C

CAS# 27503-33-9

Physalin C

2D Structure

Catalog No. BCN7918----Order now to get a substantial discount!

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Quality Control of Physalin C

3D structure

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Physalin C

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Chemical Properties of Physalin C

Cas No. 27503-33-9 SDF Download SDF
PubChem ID 101650329 Appearance Powder
Formula C28H30O9 M.Wt 510.53
Type of Compound Miscellaneous Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
SMILES CC12CC(C3(C45C1C(=O)C(O4)(C6CC=C7CC=CC(=O)C7(C6CCC5(C(=O)O3)O)C)O)C)OC(=O)C2=C
Standard InChIKey OZDVKLAQLVYYJW-VJCZVSKQSA-N
Standard InChI InChI=1S/C28H30O9/c1-13-21(31)35-18-12-23(13,2)19-20(30)27(34)16-9-8-14-6-5-7-17(29)24(14,3)15(16)10-11-26(33)22(32)36-25(18,4)28(19,26)37-27/h5,7-8,15-16,18-19,33-34H,1,6,9-12H2,2-4H3/t15-,16+,18+,19+,23+,24-,25-,26-,27-,28-/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Physalin C

The herbs of Physalis alkekengi

Biological Activity of Physalin C

DescriptionPhysalin C is a natural product from Physalis alkekengi.

Protocol of Physalin C

Structure Identification
Tetrahedron, 1970, 26(7):1743-1745.

The structure of physalin C : A bitter principle of Physalis Alkekengi var. Francheti[Reference: WebLink]

Physalin C, a bitter principle of Physalis Alkekengi var. Francheti, was isolated and the structure was established as 7-deoxyphysalin A.

Physalin C Dilution Calculator

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Physalin C Molarity Calculator

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Preparing Stock Solutions of Physalin C

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.9587 mL 9.7937 mL 19.5875 mL 39.175 mL 48.9687 mL
5 mM 0.3917 mL 1.9587 mL 3.9175 mL 7.835 mL 9.7937 mL
10 mM 0.1959 mL 0.9794 mL 1.9587 mL 3.9175 mL 4.8969 mL
50 mM 0.0392 mL 0.1959 mL 0.3917 mL 0.7835 mL 0.9794 mL
100 mM 0.0196 mL 0.0979 mL 0.1959 mL 0.3917 mL 0.4897 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Physalin C

Six new physalins from Physalis alkekengi var. franchetii and their cytotoxicity and antibacterial activity.[Pubmed:27215128]

Fitoterapia. 2016 Jul;112:144-52.

Six new physalin steroids, 7beta-methoxylisophysalin B (1), 7beta-methoxylPhysalin C (2), physalin V (3), physalin VI (4), physalin VII (5), isophysalin I (6), together with 20 known physalins (7-26) were isolated from calyces of Physalis alkekengi var. franchetii. Structures of the new compounds were revealed through 1D and 2D NMR and mass spectroscopic methods. Compounds 1-26 were evaluated for cytotoxicity against human HL-60, SMMC-7721, A-549, MCF-7 and SW-480, and the results indicated that compounds 8, 11, and 14 displayed potent cytotoxicities (IC50<5muM) in vitro. Further antibacterial assay indicated that compounds 8, 14, and 19 showed high antibacterial activities against Bacillus subtilis and Escherichia coli.

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