Neocryptotanshinone IICAS# 27468-20-8 |
Quality Control & MSDS
3D structure
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| Cas No. | 27468-20-8 | SDF | Download SDF |
| PubChem ID | 15690458 | Appearance | Powder |
| Formula | C19H22O3 | M.Wt | 298.4 |
| Type of Compound | Diterpenoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | 1-hydroxy-8,8-dimethyl-2-propan-2-yl-6,7-dihydro-5H-phenanthrene-3,4-dione | ||
| SMILES | CC(C)C1=C(C2=C(C3=C(C=C2)C(CCC3)(C)C)C(=O)C1=O)O | ||
| Standard InChIKey | UPLOJIODCUTBOZ-UHFFFAOYSA-N | ||
| Standard InChI | InChI=1S/C19H22O3/c1-10(2)14-16(20)12-7-8-13-11(6-5-9-19(13,3)4)15(12)18(22)17(14)21/h7-8,10,20H,5-6,9H2,1-4H3 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
The roots of Salvia miltiorrhiza Bge.
| Description | 1. Neocryptotanshinone inhibits lipopolysaccharide-induced inflammation in RAW264.7 macrophages by suppression of NF-κB and iNOS signaling pathways. |
| Targets | NF-kB | NOS |
Neocryptotanshinone II Dilution Calculator
Neocryptotanshinone II Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 3.3512 mL | 16.756 mL | 33.5121 mL | 67.0241 mL | 83.7802 mL |
| 5 mM | 0.6702 mL | 3.3512 mL | 6.7024 mL | 13.4048 mL | 16.756 mL |
| 10 mM | 0.3351 mL | 1.6756 mL | 3.3512 mL | 6.7024 mL | 8.378 mL |
| 50 mM | 0.067 mL | 0.3351 mL | 0.6702 mL | 1.3405 mL | 1.6756 mL |
| 100 mM | 0.0335 mL | 0.1676 mL | 0.3351 mL | 0.6702 mL | 0.8378 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Diterpenoids from Salvia miltiorrhiza.[Pubmed:10820810]
Phytochemistry. 2000 Apr;53(8):951-3.
The abietane diterpenoid, Neocryptotanshinone II, and the known 6,12-dihydroxyabieta-5,8,11,13-tetraen-7-one were isolated as minor components from the roots of Salvia miltiorrhiza. Their structures were established on the basis of spectral evidence.
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