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Pseudoginsenoside RT5

CAS# 98474-78-3

Pseudoginsenoside RT5

Catalog No. BCN1076----Order now to get a substantial discount!

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Quality Control of Pseudoginsenoside RT5

Number of papers citing our products

Chemical structure

Pseudoginsenoside RT5

3D structure

Chemical Properties of Pseudoginsenoside RT5

Cas No. 98474-78-3 SDF Download SDF
PubChem ID 21633075 Appearance White powder
Formula C36H62O10 M.Wt 654.88
Type of Compound Triterpenoids Storage Desiccate at -20°C
Solubility Soluble in chloroform, ethanol, methanol and water
Chemical Name (2R,3R,4S,5S,6R)-2-[[(3S,5R,6S,8R,9R,10R,12R,13R,14R,17S)-3,12-dihydroxy-17-[(2S,5R)-5-(2-hydroxypropan-2-yl)-2-methyloxolan-2-yl]-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-6-yl]oxy]-6-(hydroxymethyl)oxane-3,4,5-triol
SMILES CC1(C(CCC2(C1C(CC3(C2CC(C4C3(CCC4C5(CCC(O5)C(C)(C)O)C)C)O)C)OC6C(C(C(C(O6)CO)O)O)O)C)O)C
Standard InChIKey PSOUXXNNRFNUAY-JLXGCTMESA-N
Standard InChI InChI=1S/C36H62O10/c1-31(2)23(39)10-12-33(5)22-15-19(38)25-18(36(8)14-11-24(46-36)32(3,4)43)9-13-34(25,6)35(22,7)16-20(29(31)33)44-30-28(42)27(41)26(40)21(17-37)45-30/h18-30,37-43H,9-17H2,1-8H3/t18-,19+,20-,21+,22+,23-,24+,25-,26+,27-,28+,29-,30+,33+,34+,35+,36-/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Pseudoginsenoside RT5

The roots of Panax ginseng C. A. Mey.

Biological Activity of Pseudoginsenoside RT5

DescriptionPseudoginsenoside RT5 is a nartural product from Panax ginseng C. A. Mey.
In vitro

Research on dynamic accumulation of nine ginsenosides and two pseudo-ginsenosides of Panax quinquefolium root of different growth years and harvest months in Canada.[Pubmed: 25895377]

Zhong Yao Cai. 2014 Oct;37(10):1743-8.

RP-HPLC-ELSD was adopted. The analysis was performed on a Dimaonsil C18 (250 mm x 4.6 mm, 5 μm) column, the mobile phase was acetonitrile (A)-deionized water (B) in gradient elution mode.
METHODS AND RESULTS:
The flow rate was 1.0 mL/min and column temperature was set at 30 °C. The carrier gas was nitrogen with flow rate of 2.8 L/min, the drift tube temperature was 100 °C, and the injection volume was 10 μL. The principle component analysis and cluster analysis of SPSS software (version 19.0) were conducted for the data analysis. The RP-HPLC-ELSD method for determining simultaneously nine ginsenosides and two pseudoginsenosides was established. The total content of ginsenosides of one- to two-year-old was low and increased from May to September in each year. That of three- to five-year-old declined from June to July and increased from August, and was the highest in September of three- to five-year-old samples. The total content from September of three-year-old samples was similar. The content of nine ginsenosides and two pseudo-ginsenosides was relatively high in all the samples except ginsenoside Rc, which wasn't determined in some samples. The ginsenosides Rd, Rb3 and pseudo-ginsenoside F11 were higher than others. The principle component analysis results showed that ginsenosides Rg1, Re, Rb1, Rc, Rb2, Rb3, Rg3 and pseudoginsenoside F11,Pseudoginsenoside RT5 could be the characteristic ginsenosides of Panax quinquefolium root in Canada.
CONCLUSIONS:
The cluster analysis indicated that the chemical constituent and dynamic accumulation of ginsenosides of one- to two-year-old was similar except the sample of July of four-year-old and there was no obvious difference of three- to five-year-old.

Protocol of Pseudoginsenoside RT5

Structure Identification
Zhongguo Zhong Yao Za Zhi. 2003 Sep;28(9):830-3.

[Studies on saponin constituents in roots of Panax quinquefolium].[Pubmed: 15015374]

To examine the saponins constituents in roots of Panax quinquefolium cultivated in China.
METHODS AND RESULTS:
The methanol extract from roots of P. quinquefolium cultivated in Jiling province of China was extracted by chloroform and n-butanol successively. Ten pure saponins were isolated from the n-butanol extract by silica gel and RP-8 reversed-phase column chromatography. Their structures were identified by means of spectral methods and compared with known compounds. Ten saponins were isolated from P. quinquefolium. They were identified as ginsenoside Rg1(2), Re(5), Rd(7), Rc(8), Rb1(9), Rb2(10), 24(R)-ginsenoside Rg3(3), 24(R)-Pseudoginsenoside RT5(1), F11(4) and notoginsenoside K(6), respectively.
CONCLUSIONS:
This work has elucidated the saponins constituents of P. quinquefolium cultivated in Jilin province of China and has shown that compound 1 was isolated from this plant for the first time.

Pseudoginsenoside RT5 Dilution Calculator

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Pseudoginsenoside RT5 Molarity Calculator

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Preparing Stock Solutions of Pseudoginsenoside RT5

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.527 mL 7.635 mL 15.27 mL 30.5399 mL 38.1749 mL
5 mM 0.3054 mL 1.527 mL 3.054 mL 6.108 mL 7.635 mL
10 mM 0.1527 mL 0.7635 mL 1.527 mL 3.054 mL 3.8175 mL
50 mM 0.0305 mL 0.1527 mL 0.3054 mL 0.6108 mL 0.7635 mL
100 mM 0.0153 mL 0.0763 mL 0.1527 mL 0.3054 mL 0.3817 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Pseudoginsenoside RT5

[Studies on saponin constituents in roots of Panax quinquefolium].[Pubmed:15015374]

Zhongguo Zhong Yao Za Zhi. 2003 Sep;28(9):830-3.

OBJECTIVE: To examine the saponins constituents in roots of Panax quinquefolium cultivated in China. METHOD: The methanol extract from roots of P. quinquefolium cultivated in Jiling province of China was extracted by chloroform and n-butanol successively. Ten pure saponins were isolated from the n-butanol extract by silica gel and RP-8 reversed-phase column chromatography. Their structures were identified by means of spectral methods and compared with known compounds. RESULT: Ten saponins were isolated from P. quinquefolium. They were identified as ginsenoside Rg1(2), Re(5), Rd(7), Rc(8), Rb1(9), Rb2(10), 24(R)-ginsenoside Rg3(3), 24(R)-Pseudoginsenoside RT5(1), F11(4) and notoginsenoside K(6), respectively. CONCLUSION: This work has elucidated the saponins constituents of P. quinquefolium cultivated in Jilin province of China and has shown that compound 1 was isolated from this plant for the first time.

Description

Pseudoginsenoside RT5 is isolated from Panax quinquefolium.

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