Pseudolarolide Q2CAS# 1338366-22-5 |
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| Cas No. | 1338366-22-5 | SDF | Download SDF |
| PubChem ID | 101733484 | Appearance | Powder |
| Formula | C30H42O7 | M.Wt | 514.65 |
| Type of Compound | Triterpenoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | (1R,3'R,4R,5R,6R,8S,10R,12S,13S,16S,22R)-3',4,6,12,17,17-hexamethylspiro[9,18,23,24-tetraoxahexacyclo[20.2.1.01,13.04,12.05,10.016,22]pentacos-20-ene-8,5'-oxolane]-2',19-dione | ||
| SMILES | CC1CC2(CC(C(=O)O2)C)OC3C1C4(CCC56CC7(C=CC(=O)OC(C7CCC5C4(C3)C)(C)C)OO6)C | ||
| Standard InChIKey | KYSAZQMUXWZIQI-CUAOZKIYSA-N | ||
| Standard InChI | InChI=1S/C30H42O7/c1-17-13-30(14-18(2)24(32)35-30)33-19-15-27(6)21-8-7-20-25(3,4)34-22(31)9-10-28(20)16-29(21,37-36-28)12-11-26(27,5)23(17)19/h9-10,17-21,23H,7-8,11-16H2,1-6H3/t17-,18-,19-,20+,21+,23+,26-,27+,28+,29-,30+/m1/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
The peel of Pseudolarix amabilis
| Description | 1. Pseudolarolide Q exhibits strong antimicrobial activity against Gram-positive Staphylococcus aureus and Candida albicans at the MICs of 6.08 and 24.32 uM. |
| Targets | Antifection |
Pseudolarolide Q2 Dilution Calculator
Pseudolarolide Q2 Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 1.9431 mL | 9.7153 mL | 19.4307 mL | 38.8614 mL | 48.5767 mL |
| 5 mM | 0.3886 mL | 1.9431 mL | 3.8861 mL | 7.7723 mL | 9.7153 mL |
| 10 mM | 0.1943 mL | 0.9715 mL | 1.9431 mL | 3.8861 mL | 4.8577 mL |
| 50 mM | 0.0389 mL | 0.1943 mL | 0.3886 mL | 0.7772 mL | 0.9715 mL |
| 100 mM | 0.0194 mL | 0.0972 mL | 0.1943 mL | 0.3886 mL | 0.4858 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Oxidatively rearranged cycloartane triterpenoids from the seeds of Pseudolarix amabilis.[Pubmed:29171302]
Nat Prod Res. 2018 Aug;32(15):1817-1823.
One novel and eight known oxidatively rearranged cycloartane triterpenoids were isolated from the seeds of Pseudolarix amabilis. The structure of the new isolate was elucidated on extensive spectroscopic analyses. Results indicated that pseudolarolide Q (4) exhibited strong antimicrobial activity against Gram-positive Staphylococcus aureus and Candida albicans at the MICs of 6.08 and 24.32 muM, respectively. Pseudolarolide I (2) showed the 11beta-HSD1 inhibitory property at the IC50 value of 34.5 nM.
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