Ebenifoline E-II

CAS# 133740-16-6

Ebenifoline E-II

Catalog No. BCN3097----Order now to get a substantial discount!

Product Name & Size Price Stock
Ebenifoline E-II: 5mg Please Inquire In Stock
Ebenifoline E-II: 10mg Please Inquire In Stock
Ebenifoline E-II: 20mg Please Inquire Please Inquire
Ebenifoline E-II: 50mg Please Inquire Please Inquire
Ebenifoline E-II: 100mg Please Inquire Please Inquire
Ebenifoline E-II: 200mg Please Inquire Please Inquire
Ebenifoline E-II: 500mg Please Inquire Please Inquire
Ebenifoline E-II: 1000mg Please Inquire Please Inquire

Quality Control of Ebenifoline E-II

Number of papers citing our products

Chemical structure

Ebenifoline E-II

3D structure

Chemical Properties of Ebenifoline E-II

Cas No. 133740-16-6 SDF Download SDF
PubChem ID 195749 Appearance Powder
Formula C48H51NO18 M.Wt 929.9
Type of Compound Sesquiterpenoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
SMILES CC1C(C(=O)OC2C(C(C3(C(C(C4C(C3(C2(C)O)OC4(COC(=O)C5=C1N=CC=C5)C)OC(=O)C6=CC=CC=C6)OC(=O)C)OC(=O)C)COC(=O)C)OC(=O)C7=CC=CC=C7)OC(=O)C)C
Standard InChIKey PYDAEIINPZJDBO-UHFFFAOYSA-N
Standard InChI InChI=1S/C48H51NO18/c1-24-25(2)41(54)65-38-36(62-28(5)52)40(66-43(56)31-18-13-10-14-19-31)47(23-59-26(3)50)39(63-29(6)53)35(61-27(4)51)33-37(64-42(55)30-16-11-9-12-17-30)48(47,46(38,8)58)67-45(33,7)22-60-44(57)32-20-15-21-49-34(24)32/h9-21,24-25,33,35-40,58H,22-23H2,1-8H3
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Biological Activity of Ebenifoline E-II

DescriptionEbenifoline E-II is a natural product from Euonymus laxiflorus.

Protocol of Ebenifoline E-II

Structure Identification
J Nat Prod. 2003 Apr;66(4):554-7.

A novel NO-production-inhibiting triterpene and cytotoxicity of known alkaloids from Euonymus laxiflorus.[Pubmed: 12713415 ]


METHODS AND RESULTS:
A new triterpene, laxifolone A (1), four known sesquiterpene alkaloids, Ebenifoline E-II (2), carigorinine E (3), euojaponine C (4), and emarginatine E (5), and six triterpenoids, 3-hydroxyolean-12-en-22,29-gamma-lactone, 3,11-dioxo-beta-amyrene, 3beta,22alpha-dihydroxyolean-12-en-29-oic acid, 28,29-dihydroxyfriedelan-3-one, 29-hydroxy-3-oxo-D:A-friedooleanan-28-oic acid, and putranjivadione, were isolated from the stems and leaves of Euonymus laxiflorus.
CONCLUSIONS:
Structural elucidations of these compounds were established by spectral analysis. Compound 1 displayed significant nitric oxide (NO) inhibitory effect.

Ebenifoline E-II Dilution Calculator

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Ebenifoline E-II Molarity Calculator

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Preparing Stock Solutions of Ebenifoline E-II

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.0754 mL 5.3769 mL 10.7538 mL 21.5077 mL 26.8846 mL
5 mM 0.2151 mL 1.0754 mL 2.1508 mL 4.3015 mL 5.3769 mL
10 mM 0.1075 mL 0.5377 mL 1.0754 mL 2.1508 mL 2.6885 mL
50 mM 0.0215 mL 0.1075 mL 0.2151 mL 0.4302 mL 0.5377 mL
100 mM 0.0108 mL 0.0538 mL 0.1075 mL 0.2151 mL 0.2688 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Ebenifoline E-II

A novel NO-production-inhibiting triterpene and cytotoxicity of known alkaloids from Euonymus laxiflorus.[Pubmed:12713415]

J Nat Prod. 2003 Apr;66(4):554-7.

A new triterpene, laxifolone A (1), four known sesquiterpene alkaloids, Ebenifoline E-II (2), carigorinine E (3), euojaponine C (4), and emarginatine E (5), and six triterpenoids, 3-hydroxyolean-12-en-22,29-gamma-lactone, 3,11-dioxo-beta-amyrene, 3beta,22alpha-dihydroxyolean-12-en-29-oic acid, 28,29-dihydroxyfriedelan-3-one, 29-hydroxy-3-oxo-D:A-friedooleanan-28-oic acid, and putranjivadione, were isolated from the stems and leaves of Euonymus laxiflorus. Structural elucidations of these compounds were established by spectral analysis. Compound 1 displayed significant nitric oxide (NO) inhibitory effect.

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