EuonymineCAS# 150881-01-9 |
- Evonine
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| Cas No. | 150881-01-9 | SDF | Download SDF |
| PubChem ID | 44593671 | Appearance | Powder |
| Formula | C38H47NO18 | M.Wt | 805.8 |
| Type of Compound | Sesquiterpenoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| SMILES | CC1C(C(=O)OC2C(C(C3(C(C(C4C(C3(C2(C)O)OC4(COC(=O)C5=C1N=CC=C5)C)OC(=O)C)OC(=O)C)OC(=O)C)COC(=O)C)OC(=O)C)OC(=O)C)C | ||
| Standard InChIKey | PBFGAFDJVQAMRS-KXCMQXIBSA-N | ||
| Standard InChI | InChI=1S/C38H47NO18/c1-16-17(2)33(46)56-30-28(52-20(5)42)32(55-23(8)45)37(15-49-18(3)40)31(54-22(7)44)27(51-19(4)41)25-29(53-21(6)43)38(37,36(30,10)48)57-35(25,9)14-50-34(47)24-12-11-13-39-26(16)24/h11-13,16-17,25,27-32,48H,14-15H2,1-10H3/t16?,17?,25-,27-,28+,29-,30+,31-,32+,35+,36+,37-,38+/m1/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | Peritassine A is a natural product from Tripterygium wilfordii Hook. f. |
| In vitro | Sesquiterpene alkaloids from Tripterygium hypoglaucum and Tripterygium wilfordii: a new class of potent anti-HIV agents.[Pubmed: 10757718]J Nat Prod. 2000 Mar;63(3):357-61.
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| Structure Identification | Zhong Yao Cai. 2012 Jul;35(7):1083-7.Study on chemical constituents from the root bark of Tripterygium hypoglaucum.[Pubmed: 23252270]To study the chemical constituents of the root bark of Tripterygium hypoglaucum.
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Euonymine Dilution Calculator
Euonymine Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 1.241 mL | 6.205 mL | 12.41 mL | 24.8201 mL | 31.0251 mL |
| 5 mM | 0.2482 mL | 1.241 mL | 2.482 mL | 4.964 mL | 6.205 mL |
| 10 mM | 0.1241 mL | 0.6205 mL | 1.241 mL | 2.482 mL | 3.1025 mL |
| 50 mM | 0.0248 mL | 0.1241 mL | 0.2482 mL | 0.4964 mL | 0.6205 mL |
| 100 mM | 0.0124 mL | 0.0621 mL | 0.1241 mL | 0.2482 mL | 0.3103 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Sesquiterpene alkaloids from Tripterygium hypoglaucum and Tripterygium wilfordii: a new class of potent anti-HIV agents.[Pubmed:10757718]
J Nat Prod. 2000 Mar;63(3):357-61.
Five new sesquiterpene pyridine alkaloids [triptonines A (1) and B (2), and wilfordinines A (3), B (4), and C (5)] and two known compounds (peritassine A and hypoglaunine C) were isolated from Tripterygium hypoglaucum and a clinically used extract of Tripterygium wilfordii. The structures of 1-5 were elucidated by spectroscopic methods. The anti-HIV activity of 1, 2, and several related compounds was evaluated. Triptonine B (2) demonstrated potent anti-HIV activity with an EC(50) value of <0.10 microg/mL and an in vitro therapeutic index value of >1000.
[Study on chemical constituents from the root bark of Tripterygium hypoglaucum].[Pubmed:23252270]
Zhong Yao Cai. 2012 Jul;35(7):1083-7.
OBJECTIVE: To study the chemical constituents of the root bark of Tripterygium hypoglaucum. METHODS: Column chromatography was used to separate the chemical constituents. The structures were determined by application of spectroscopic (NMR, MS) and chemical methods. RESULTS: Eleven compounds were isolated and identified as 4'-0-(-) methylepigallocatechin (1),3,4-dimethoxyphenyl-beta-D-glucopyranoside (2), 3,4,5-trimethoxyphenyl-f-D-glucopyranoside (3), (2R,3R)-3,5,7,3',5'-pentahydroxyflavan (4), 2-O-deacetyleuonine (5), tripfordine C (6), peritassine A (7) hypoglaunine C (8), wilfortrine (9), wilforgine (10) and wilfordine (11). CONCLUSION: Compounds 1-6 are isolated from this plant for the first time.
