Wilfornine ACAS# 345954-00-9 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
Cas No. | 345954-00-9 | SDF | Download SDF |
PubChem ID | 44584747 | Appearance | Powder |
Formula | C45H51NO20 | M.Wt | 925.9 |
Type of Compound | Sesquiterpenoids | Storage | Desiccate at -20°C |
Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
Chemical Name | [(1S,3R,15R,18S,19R,20R,21R,22S,23R,24R,25R,26S)-19,20,22,23,25-pentaacetyloxy-21-(acetyloxymethyl)-26-hydroxy-3,15,26-trimethyl-6,16-dioxo-2,5,17-trioxa-11-azapentacyclo[16.7.1.01,21.03,24.07,12]hexacosa-7(12),8,10-trien-15-yl] benzoate | ||
SMILES | CC(=O)OCC12C(C(C3C(C14C(C(C(C2OC(=O)C)OC(=O)C)OC(=O)C(CCC5=C(C=CC=N5)C(=O)OCC3(O4)C)(C)OC(=O)C6=CC=CC=C6)(C)O)OC(=O)C)OC(=O)C)OC(=O)C | ||
Standard InChIKey | YJDNHPICMWQYIV-VTPOCOLISA-N | ||
Standard InChI | InChI=1S/C45H51NO20/c1-22(47)57-21-44-36(62-26(5)51)32(59-23(2)48)31-34(61-25(4)50)45(44)43(9,56)35(33(60-24(3)49)37(44)63-27(6)52)64-40(55)41(7,65-38(53)28-14-11-10-12-15-28)18-17-30-29(16-13-19-46-30)39(54)58-20-42(31,8)66-45/h10-16,19,31-37,56H,17-18,20-21H2,1-9H3/t31-,32-,33+,34-,35+,36-,37+,41-,42+,43+,44-,45+/m1/s1 | ||
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. |
Description | Wilfornine A is a natural product from Schisandra sphenanthera. |
Kinase Assay | Immunosuppressive sesquiterpene alkaloids from Tripterygium wilfordii.[Pubmed: 11374948]J Nat Prod. 2001 May;64(5):582-7.Nine new sesquiterpene pyridine alkaloids [Wilfornine A (1), wilfornine B (2), wilfornine C (3), wilfornine D (4), wilfornine E (5), wilfornine F (8), and wilfornine G (9); wilfordinines I (6) and J (7)] and six known compounds (10-15) were isolated from a clinically used extract (T(II)) of Tripterygium wilfordii.
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Wilfornine A Dilution Calculator
Wilfornine A Molarity Calculator
1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
1 mM | 1.08 mL | 5.4002 mL | 10.8003 mL | 21.6006 mL | 27.0008 mL |
5 mM | 0.216 mL | 1.08 mL | 2.1601 mL | 4.3201 mL | 5.4002 mL |
10 mM | 0.108 mL | 0.54 mL | 1.08 mL | 2.1601 mL | 2.7001 mL |
50 mM | 0.0216 mL | 0.108 mL | 0.216 mL | 0.432 mL | 0.54 mL |
100 mM | 0.0108 mL | 0.054 mL | 0.108 mL | 0.216 mL | 0.27 mL |
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. |
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Immunosuppressive sesquiterpene alkaloids from Tripterygium wilfordii.[Pubmed:11374948]
J Nat Prod. 2001 May;64(5):582-7.
Nine new sesquiterpene pyridine alkaloids [wilfornines A (1), B (2), C (3), D (4), E (5), F (8), and G (9); wilfordinines I (6) and J (7)] and six known compounds (10-15) were isolated from a clinically used extract (T(II)) of Tripterygium wilfordii. The structures of 1-9 were elucidated by spectroscopic and chemical methods. The inhibitory effects on cytokine production of 1-3 and several related compounds were evaluated. Compounds 10 and 14 showed significant inhibitory effects on cytokine production.