Puerol ACAS# 152784-32-2 |
Quality Control & MSDS
3D structure
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| Cas No. | 152784-32-2 | SDF | Download SDF |
| PubChem ID | 14691941 | Appearance | Powder |
| Formula | C17H14O5 | M.Wt | 298.3 |
| Type of Compound | Phenols | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | 3-(2,4-dihydroxyphenyl)-2-[(4-hydroxyphenyl)methyl]-2H-furan-5-one | ||
| SMILES | C1=CC(=CC=C1CC2C(=CC(=O)O2)C3=C(C=C(C=C3)O)O)O | ||
| Standard InChIKey | AYXZYYUMEUUTRQ-UHFFFAOYSA-N | ||
| Standard InChI | InChI=1S/C17H14O5/c18-11-3-1-10(2-4-11)7-16-14(9-17(21)22-16)13-6-5-12(19)8-15(13)20/h1-6,8-9,16,18-20H,7H2 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
The stem bark of Sophora japonica.
| Description | 1. Puerol A exhibits potent inhibitory effects on aldose reductase with IC50 values of 6.4 uM. 2. dl-Puerol A has antioxdiant activity, it shows inhibitory effects on copper ion-induced protein oxidative modification of mouse brain homogenate in vitro. |
Puerol A Dilution Calculator
Puerol A Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 3.3523 mL | 16.7616 mL | 33.5233 mL | 67.0466 mL | 83.8082 mL |
| 5 mM | 0.6705 mL | 3.3523 mL | 6.7047 mL | 13.4093 mL | 16.7616 mL |
| 10 mM | 0.3352 mL | 1.6762 mL | 3.3523 mL | 6.7047 mL | 8.3808 mL |
| 50 mM | 0.067 mL | 0.3352 mL | 0.6705 mL | 1.3409 mL | 1.6762 mL |
| 100 mM | 0.0335 mL | 0.1676 mL | 0.3352 mL | 0.6705 mL | 0.8381 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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A new isoflavone glycoside from the stem bark of Sophora japonica.[Pubmed:20803118]
Arch Pharm Res. 2010 Aug;33(8):1165-8.
A new isoflavone glycoside, 6-methoxy-7-hydroxy-4'-O-beta-D-glucosyl isoflavone, glycitein-4'-O-beta-D-glucoside (10), along with nine known flavonoids, were isolated from the stem bark of Sophora japonica. The structures of these compounds were determined by analysis of spectroscopic data (1D -, 2D - NMR and HRMS). The inhibitory effects of all the isolated compounds on aldose reductase were evaluated in vitro. Among these compounds, daidzein (1), Puerol A (4), and paratensein-7-O-glucoside (9) exhibited potent inhibitory effects, with IC(50) values of 3.2, 6.4, and 1.9 microM, respectively.
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