Pueroside BCAS# 100692-54-4 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
Cas No. | 100692-54-4 | SDF | Download SDF |
PubChem ID | N/A | Appearance | Powder |
Formula | C30H36O15 | M.Wt | 636.6 |
Type of Compound | Flavonoids | Storage | Desiccate at -20°C |
Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
||
About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
||
Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. |
Description | Pueroside B may can treat coronary heart disease, it can interact with two or more targets[peroxisome proliferator activated receptor γ (PPAR-γ), angiotensin-converting enzyme (ACE), hydroxymethylglutaryl coenzyme A receptor (HMGR), cyclooxygenase-2 (COX2), and thrombin]. |
Targets | PPAR | COX | HMGR |
In vitro | Protective effects of puerariae radix extract and its single compounds on methylglyoxal-induced apoptosis in human retinal pigment epithelial cells.[Pubmed: 24486213]J Ethnopharmacol. 2014 Mar 28;152(3):594-8.
In Korea, Puerariae radix is a medicinal plant traditionally used to treat various diseases including diabetes mellitus. To provide pharmacological basis for Puerariae radix in the treatment of diabetes, we investigated the protective effects of the ethanolic extract and its single compounds on apoptosis associated with glycation in human retinal pigment epithelial (RPE) cells.
Molecular Docking in Xin-Ke-Shu Preparation's Multi-Target Effect on Coronary Heart Disease.[Reference: WebLink]ACTA PHYSICO-CHIMICA SINICA, 2012, 28(5).Xin-Ke-Shu (XKS), a traditional Chinese medicine (TCM) preparation, has been widely used for treatment of coronary heart disease (CHD) in China. However, the active constituents of XKS and their interactions with targets remain unclear.
|
Pueroside B Dilution Calculator
Pueroside B Molarity Calculator
1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
1 mM | 1.5708 mL | 7.8542 mL | 15.7085 mL | 31.4169 mL | 39.2711 mL |
5 mM | 0.3142 mL | 1.5708 mL | 3.1417 mL | 6.2834 mL | 7.8542 mL |
10 mM | 0.1571 mL | 0.7854 mL | 1.5708 mL | 3.1417 mL | 3.9271 mL |
50 mM | 0.0314 mL | 0.1571 mL | 0.3142 mL | 0.6283 mL | 0.7854 mL |
100 mM | 0.0157 mL | 0.0785 mL | 0.1571 mL | 0.3142 mL | 0.3927 mL |
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. |
Calcutta University
University of Minnesota
University of Maryland School of Medicine
University of Illinois at Chicago
The Ohio State University
University of Zurich
Harvard University
Colorado State University
Auburn University
Yale University
Worcester Polytechnic Institute
Washington State University
Stanford University
University of Leipzig
Universidade da Beira Interior
The Institute of Cancer Research
Heidelberg University
University of Amsterdam
University of Auckland
TsingHua University
The University of Michigan
Miami University
DRURY University
Jilin University
Fudan University
Wuhan University
Sun Yat-sen University
Universite de Paris
Deemed University
Auckland University
The University of Tokyo
Korea University
- Formononetin-8-C-beta-D-apiofuranosyl-(1->6)-O-beta-D-glucopyranoside
Catalog No.:BCN8767
CAS No.:1147858-78-3
- Daidzein-4'-glucoside
Catalog No.:BCN8766
CAS No.:58970-69-7
- Rhamnocitrin 3-apiosyl-(1→2)-glucoside
Catalog No.:BCN8765
CAS No.:148031-68-9
- Orientalide
Catalog No.:BCN8764
CAS No.:72704-05-3
- 3,7,23,24-tetrahydroxycucurbita-5,25-dien-19-al
Catalog No.:BCN8763
CAS No.:1446447-97-7
- (1,5E,11E)-tridecatriene-7,9-diyne-3,4-diacetate
Catalog No.:BCN8762
CAS No.:201012-14-8
- Rhamnocitrin 3-glucoside
Catalog No.:BCN8761
CAS No.:41545-37-3
- Microgrewiapine A
Catalog No.:BCN8760
CAS No.:1420777-30-5
- ent-16beta,17-dihydroxy-9(11)-kauren-19-oic acid
Catalog No.:BCN8759
CAS No.:55483-24-4
- Torosachrysone 8-O-beta-gentiobioside
Catalog No.:BCN8758
CAS No.:94356-13-5
- Ampelopsin G
Catalog No.:BCN8757
CAS No.:151487-09-1
- Yuanhuanin
Catalog No.:BCN8756
CAS No.:83133-14-6
- Momordicoside X
Catalog No.:BCN8769
CAS No.:1333321-50-8
- Pueroside C
Catalog No.:BCN8770
CAS No.:112343-16-5
- 1,7-Diphenyl-5-hydroxy-4,6-hepten-3-one
Catalog No.:BCN8771
CAS No.:87095-77-0
- Genistein 7-O-beta-D-glucopyranoside-4'-O-[alpha-L-rhamnopyranosyl-(1->2)-beta-D-glucopyranoside]
Catalog No.:BCN8772
CAS No.:70404-42-1
- Citrusin B
Catalog No.:BCN8773
CAS No.:105279-10-5
- Licoricesaponin H2(18beta,20alpha-Glycyrrhizic acid)
Catalog No.:BCN8774
CAS No.:118441-85-3
- 3-O-[5'''-O-feruloyl-beta-D-apiofuranosyl(1'''->2'')-beta-D-glucopyranosyl] rhamnocitrin
Catalog No.:BCN8775
CAS No.:148210-00-8
- Yuanhunine
Catalog No.:BCN8776
CAS No.:104387-15-7
- Silychristin B
Catalog No.:BCN8777
CAS No.:879325-58-3
- Maculosidin
Catalog No.:BCN8778
CAS No.:522-19-0
- Isonardosinone
Catalog No.:BCN8779
CAS No.:27062-01-7
- Dehydrojuncusol
Catalog No.:BCN8780
CAS No.:117824-04-1
Protective effects of puerariae radix extract and its single compounds on methylglyoxal-induced apoptosis in human retinal pigment epithelial cells.[Pubmed:24486213]
J Ethnopharmacol. 2014 Mar 28;152(3):594-8.
ETHNOPHARMACOLOGICAL RELEVANCE: In Korea, Puerariae radix is a medicinal plant traditionally used to treat various diseases including diabetes mellitus. To provide pharmacological basis for Puerariae radix in the treatment of diabetes, we investigated the protective effects of the ethanolic extract and its single compounds on apoptosis associated with glycation in human retinal pigment epithelial (RPE) cells. MATERIALS AND METHODS: In the present work, a quantified ethanolic extract or single compounds of Puerariae radix were selected to determine its anti-apoptotic effect in human RPE cells cultured with methylglyoxal (MG), which is a stimulator of glycation. To assess the protective effect of the extract or single compounds, the cytotoxicity assessment was performed using an MTT assay in the human RPE cells. Selected active compounds or extracts were tested by FACS analysis with annexin V staining for apoptosis. RESULTS: Daidzein (1), daidzin (2), puerarin (3), 3'-hydroxy-daidzein 8-C-apiosyl (1-->6) glucoside (4), and daidzein 8-C-apiosyl (1-->6) glucoside (5), and Pueroside B (6) were isolated from an ethanolic extract of Puerariae radix. MG-induced apoptosis was completely inhibited by Puerariae radix, ethanolic extract, and single compounds. Of the six major compounds, daidzin (2) and 3'-hydroxy-daidzein 8-C-apiosyl (1-->6) glucoside (4) significantly inhibited MG-induced apoptosis. CONCLUSION: Our results provide the first evidence that, due to its anti-glycation effect, Puerariae radix extract could inhibit MG-induced apoptosis in the cultured human RPE cells. These data suggest that Puerariae radix extract, especially its single compounds daidzin and 3'-hydroxy-daidzein 8-C-apiosyl (1-->6) glucoside, has potential utility as a preventive agent for glycation-related diabetic retinopathy.