RA VIICAS# 86229-97-2 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
Cas No. | 86229-97-2 | SDF | Download SDF |
PubChem ID | 3034401 | Appearance | Powder |
Formula | C41H50N6O9 | M.Wt | 770.9 |
Type of Compound | Alkaloids | Storage | Desiccate at -20°C |
Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
SMILES | CC1C(=O)NC(C(=O)N(C(C(=O)NC(C(=O)N(C2CC3=CC=C(C=C3)OC4=C(C=CC(=C4)CC(C(=O)N1)N(C2=O)C)OC)C)C)CC5=CC=C(C=C5)OC)C)C | ||
Standard InChIKey | MBQKTLYFUYNAPZ-FEZMQHRXSA-N | ||
Standard InChI | InChI=1S/C41H50N6O9/c1-23-36(48)43-24(2)39(51)45(4)31(19-26-9-14-29(54-7)15-10-26)38(50)44-25(3)40(52)47(6)33-20-27-11-16-30(17-12-27)56-35-22-28(13-18-34(35)55-8)21-32(37(49)42-23)46(5)41(33)53/h9-18,22-25,31-33H,19-21H2,1-8H3,(H,42,49)(H,43,48)(H,44,50)/t23-,24+,25+,31+,32+,33+/m1/s1 | ||
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
||
About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
||
Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. |
Description | 1. RA VII is an antitumour agent, shows cytotoxic activity against P-388 cells. 2. RA VII causes the conformational change of F-actin and the stabilization of actin filaments to induce G2 arrest. |
RA VII Dilution Calculator
RA VII Molarity Calculator
1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
1 mM | 1.2972 mL | 6.4859 mL | 12.9719 mL | 25.9437 mL | 32.4296 mL |
5 mM | 0.2594 mL | 1.2972 mL | 2.5944 mL | 5.1887 mL | 6.4859 mL |
10 mM | 0.1297 mL | 0.6486 mL | 1.2972 mL | 2.5944 mL | 3.243 mL |
50 mM | 0.0259 mL | 0.1297 mL | 0.2594 mL | 0.5189 mL | 0.6486 mL |
100 mM | 0.013 mL | 0.0649 mL | 0.1297 mL | 0.2594 mL | 0.3243 mL |
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. |
Calcutta University
University of Minnesota
University of Maryland School of Medicine
University of Illinois at Chicago
The Ohio State University
University of Zurich
Harvard University
Colorado State University
Auburn University
Yale University
Worcester Polytechnic Institute
Washington State University
Stanford University
University of Leipzig
Universidade da Beira Interior
The Institute of Cancer Research
Heidelberg University
University of Amsterdam
University of Auckland
TsingHua University
The University of Michigan
Miami University
DRURY University
Jilin University
Fudan University
Wuhan University
Sun Yat-sen University
Universite de Paris
Deemed University
Auckland University
The University of Tokyo
Korea University
- Valeriotriate B
Catalog No.:BCN6751
CAS No.:862255-64-9
- Mirodenafil
Catalog No.:BCC5254
CAS No.:862189-95-5
- Nandrolone undecylate
Catalog No.:BCC9090
CAS No.:862-89-5
- Anamorelin hydrochloride
Catalog No.:BCC1364
CAS No.:861998-00-7
- 7-Methoxy-3,4-dihydro-1-naphthalenylacetonitrile
Catalog No.:BCC8781
CAS No.:861960-34-1
- 2''-O-Beta-L-Galorientin
Catalog No.:BCN3804
CAS No.:861691-37-4
- A-740003
Catalog No.:BCC1322
CAS No.:861393-28-4
- SKF 86466 hydrochloride
Catalog No.:BCC7795
CAS No.:86129-54-6
- Fmoc-D-Trp-OH
Catalog No.:BCC3559
CAS No.:86123-11-7
- Fmoc-D-Phe-OH
Catalog No.:BCC3537
CAS No.:86123-10-6
- 5'-Fluoroindirubinoxime
Catalog No.:BCC6104
CAS No.:861214-33-7
- A 844606
Catalog No.:BCC6200
CAS No.:861119-08-6
- Imatinib hydrochloride
Catalog No.:BCC1644
CAS No.:862366-25-4
- LY2228820
Catalog No.:BCC2528
CAS No.:862507-23-1
- IKK-3 Inhibitor
Catalog No.:BCC1643
CAS No.:862812-98-4
- Salvianan
Catalog No.:BCN3545
CAS No.:862832-46-0
- Ganoderic acid TR
Catalog No.:BCN3207
CAS No.:862893-75-2
- Isoiridogermanal
Catalog No.:BCN7613
CAS No.:86293-25-6
- 10-Hydroxycanthin-6-one
Catalog No.:BCN3906
CAS No.:86293-41-6
- alpha-Amyrin acetate
Catalog No.:BCN4410
CAS No.:863-76-3
- Azilsartan Medoxomil
Catalog No.:BCC5021
CAS No.:863031-21-4
- Azilsartan medoxomil monopotassium
Catalog No.:BCC4089
CAS No.:863031-24-7
- Impurity C of Calcitriol
Catalog No.:BCC5384
CAS No.:86307-44-0
- Dasatinib monohydrate
Catalog No.:BCN2177
CAS No.:863127-77-9
Aza-cycloisodityrosine analogue of RA-VII, an antitumor bicyclic hexapeptide.[Pubmed:24268554]
Bioorg Med Chem Lett. 2013 Dec 15;23(24):6728-31.
An aza-cycloisodityrosine analogue of RA-VII, 3, was designed and synthesized. The key aza-cycloisodityrosine unit was prepared by copper(II)-acetate-mediated intramolecular phenylamine/arylboronic acid coupling of dipeptide followed by connection with the tetrapeptide segment to afford a hexapeptide. Subsequent macrocyclization of the hexapeptide with EDC . HCl and HOOBt under dilute conditions gave 3. Analogue 3 showed significant cytotoxic activity against human promyelocytic leukemia HL-60 cells and human colon carcinoma HCT-116 cells, but its activity was weaker than that of parent peptide RA-VII (1).
Synthesis of [Tyr-5-Psi(CH2NMe)-Tyr-6]RA-VII, a reduced peptide bond analogue of RA-VII, an antitumor bicyclic hexapeptide.[Pubmed:22460024]
Bioorg Med Chem Lett. 2012 Apr 15;22(8):2757-9.
A reduced peptide bond analogue of RA-VII, [Tyr-5-Psi(CH(2)NMe)-Tyr-6]RA-VII (3), was designed and synthesized. The key reduced cycloisodityrosine unit was prepared by reduction of the cycloisodityrosine derived from natural RA-VII, followed by connection with the tetrapeptide segment to afford a hexapeptide. Subsequent macrocyclization of the hexapeptide with FDPP under dilute conditions gave 3. Analogue 3 showed cytotoxic activity against P-388 cells, but its activity was much weaker than that of parent peptide RA-VII.