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Rhodiocyanoside A

CAS# 168433-86-1

Rhodiocyanoside A

Catalog No. BCN7852----Order now to get a substantial discount!

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Rhodiocyanoside A: 5mg $253 In Stock
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Quality Control of Rhodiocyanoside A

Number of papers citing our products

Chemical structure

Rhodiocyanoside A

3D structure

Chemical Properties of Rhodiocyanoside A

Cas No. 168433-86-1 SDF Download SDF
PubChem ID 6442274 Appearance Powder
Formula C11H17NO6 M.Wt 259.26
Type of Compound Miscellaneous Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (Z)-2-methyl-4-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxybut-2-enenitrile
SMILES CC(=CCOC1C(C(C(C(O1)CO)O)O)O)C#N
Standard InChIKey ZMELGIPFIBWPHX-GMLQCYRESA-N
Standard InChI InChI=1S/C11H17NO6/c1-6(4-12)2-3-17-11-10(16)9(15)8(14)7(5-13)18-11/h2,7-11,13-16H,3,5H2,1H3/b6-2-/t7-,8-,9+,10-,11-/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Rhodiocyanoside A

The underground parts of Rhodiola quadrifida.

Biological Activity of Rhodiocyanoside A

Description1. Rhodiocyanoside A has antiallergic activity, it exhibits inhibitory activity on the histamine release from rat peritoneal exudate cells sensitized with anti-DNP IgE and inhibits the PCA reaction in rats.
TargetsHistamine Receptor

Rhodiocyanoside A Dilution Calculator

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Rhodiocyanoside A Molarity Calculator

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Preparing Stock Solutions of Rhodiocyanoside A

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.8571 mL 19.2857 mL 38.5713 mL 77.1426 mL 96.4283 mL
5 mM 0.7714 mL 3.8571 mL 7.7143 mL 15.4285 mL 19.2857 mL
10 mM 0.3857 mL 1.9286 mL 3.8571 mL 7.7143 mL 9.6428 mL
50 mM 0.0771 mL 0.3857 mL 0.7714 mL 1.5429 mL 1.9286 mL
100 mM 0.0386 mL 0.1929 mL 0.3857 mL 0.7714 mL 0.9643 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Rhodiocyanoside A

Phytochemical characterization of an adaptogenic preparation from Rhodiola heterodonta.[Pubmed:19768982]

Nat Prod Commun. 2009 Aug;4(8):1053-8.

The phytochemical constituents of a biologically active, standardized, 80% ethanol extract of Rhodiola heterodonta were characterized. The extract was fractionated over a Sephadex LH-20 column to afford two main fractions representing two classes of secondary metabolites: phenylethanoids and proanthocyanidins. This fractionation facilitated the identification and quantification of individual compounds in the fractions and sub-fractions using HPLC, and LC-MS. The major compounds in the phenylethanoid fraction were heterodontoside, tyrosol methyl ether, salidroside, viridoside, mongrhoside, tyrosol, and the cyanogenic glucoside Rhodiocyanoside A. These seven compounds comprised 17.4% of the EtOH extract. Proanthocyanidins ranged from oligomers to polymers based on epigallocatechin and gallate units. The main identified oligomeric compounds in the proanthocyanidin fraction were epigallocatechin gallate, epigallocatechin-epigallocatechin-3-O-gallate and 3-O-galloyl-epigallocatechin-epigallocatechin-3-O-gallate, which constituted 1.75% of the ethanol extract. Tyrosol methyl ether, mongrhoside, and the two proanthocyanidin dimers were reported for the first time from this species in this study. Intraperitoneal injection of the 80% ethanol extract increased survival time of mice under hypoxia by 192%, as an indication of adaptogenic activity.

Rhodiocyanosides A and B, new antiallergic cyanoglycosides from Chinese natural medicine "si lie hong jing tian", the underground part of Rhodiola quadrifida (Pall.) Fisch. et Mey.[Pubmed:7586066]

Chem Pharm Bull (Tokyo). 1995 Jul;43(7):1245-7.

Two new antiallergic cyanoglycosides named rhodiocyanosides A and B were isolated from the Chinese natural medicine "Si Lie Hong Jing Tian" (Shiretsukoukeiten in Japanese), the underground part of Rhodiola quadrifida (Pall.) Fisch. et Mey., together with two new glycosides, octyl alpha-L-arabinopyranosyl(1-6)-beta-D-glucopyranoside and gossypetin 7-O-beta-D-glucopyranosyl(1-3)-alpha-L-rhamnopyranoside. Their chemical structures were determined on the basis of chemical and physicochemical evidence. Rhodiocyanosides A and B exhibited inhibitory activity on the histamine release from rat peritoneal exudate cells sensitized with anti-DNP IgE. In addition, Rhodiocyanoside A was found to inhibit the PCA reaction in rats.

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