SecoxyloganinCAS# 58822-47-2 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
Cas No. | 58822-47-2 | SDF | Download SDF |
PubChem ID | 162868 | Appearance | Colorless-beige crystals |
Formula | C17H24O11 | M.Wt | 404.4 |
Type of Compound | Iridoids | Storage | Desiccate at -20°C |
Synonyms | Secologanoside 11-methyl ester | ||
Solubility | Soluble in methan | ||
Chemical Name | 2-[(2S,3R,4S)-3-ethenyl-5-methoxycarbonyl-2-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,4-dihydro-2H-pyran-4-yl]acetic acid | ||
SMILES | COC(=O)C1=COC(C(C1CC(=O)O)C=C)OC2C(C(C(C(O2)CO)O)O)O | ||
Standard InChIKey | MQLSOVRLZHTATK-PEYNGXJCSA-N | ||
Standard InChI | InChI=1S/C17H24O11/c1-3-7-8(4-11(19)20)9(15(24)25-2)6-26-16(7)28-17-14(23)13(22)12(21)10(5-18)27-17/h3,6-8,10,12-14,16-18,21-23H,1,4-5H2,2H3,(H,19,20)/t7-,8+,10-,12-,13+,14-,16+,17+/m1/s1 | ||
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. |
Description | Secoxyloganin possesses hepato- protective, cytotoxic, and antibacterial activities, it has the perfect protective effect on PRRSV infected cell and with the minimum protection concentration of 6. 25 Âμg/mL. |
Targets | Antifection |
In vitro | Cytotoxic activity of Guettarda pohliana Müll. Arg. (Rubiaceae).[Pubmed: 23387288]Nat Prod Res. 2013;27(18):1677-81.
Screening and identification of the antibacterial bioactive compounds from Lonicera japonica Thunb. leaves.[Pubmed: 23265495]Food Chem. 2013 May 1;138(1):327-33.Our aim was to screen for antibacterial bioactive compounds from Lonicera japonica leaves. Staphylococcus aureus and Escherichia coli were used as the indicator bacteria.
Bacteriostatic assay-guided extraction and stepwise partitioning of the samples yielded five compounds of interest.
CHEMICAL CONSTITUENTS IN FLOWER BUDS OF LONICERA JAPONICA THUNB.[Reference: WebLink]Chemistry & Industry of Forest Products, 2005, 25(3):29-32.Active constituents were isolated from the flower buds of Lonicera japonica Thunb. They were extracted with 70 % alcohol, then fractioned successively with petroleum ether, ethyl acetate and n-butanol.
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Cell Research | Isolation and identification of chemical constituents in effective fraction anti-PRRSV of the branches and leaves of the Lonicera japonica.[Reference: WebLink]Journal of Huazhong Normal University, 2013,52(2):213.The antiviral effect of the extracts of the Lonicera japonica leaves on PRRSV in vitro was evaluated by determining the minimum protection concentration on PRRSV infected Marc-145 cell and TCID50.
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Structure Identification | Zhong Yao Cai. 2014 Aug;37(8):1383-5.Chemical constituents from flower of Lonicera fragrantissima。[Pubmed: 25726645]To study the chemical constituents from the flower of Lonicera fragrantissima.
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Secoxyloganin Dilution Calculator
Secoxyloganin Molarity Calculator
1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
1 mM | 2.4728 mL | 12.364 mL | 24.728 mL | 49.456 mL | 61.82 mL |
5 mM | 0.4946 mL | 2.4728 mL | 4.9456 mL | 9.8912 mL | 12.364 mL |
10 mM | 0.2473 mL | 1.2364 mL | 2.4728 mL | 4.9456 mL | 6.182 mL |
50 mM | 0.0495 mL | 0.2473 mL | 0.4946 mL | 0.9891 mL | 1.2364 mL |
100 mM | 0.0247 mL | 0.1236 mL | 0.2473 mL | 0.4946 mL | 0.6182 mL |
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. |
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Screening and identification of the antibacterial bioactive compounds from Lonicera japonica Thunb. leaves.[Pubmed:23265495]
Food Chem. 2013 May 1;138(1):327-33.
Our aim was to screen for antibacterial bioactive compounds from Lonicera japonica leaves. Staphylococcus aureus and Escherichia coli were used as the indicator bacteria. Bacteriostatic assay-guided extraction and stepwise partitioning of the samples yielded five compounds of interest. Antimicrobial activities of the compounds were determined using a disk diffusion assay. Extracts, fractions, and compounds from L. japonica leaves possessed considerable antibacterial activities against the tested bacterial strains and the most active fraction was attributed to J3B2, which primarily contained 3,5-di-O-caffeoylquinic acid and 4,5-di-O-caffeoylquinic acid. Meanwhile, five bacteriostatic constituents were isolated (3-O-caffeoylquinic acid, Secoxyloganin, luteoloside, 3,5-di-O-caffeoylquinic acid and 4,5-di-O-caffeoylquinic acid), among which, Secoxyloganin was isolated for the first time from leaves. The antibacterial activity of the compounds was in the order of 3,5-bis-O-caffeoyl quinic acid, 4,5-bis-O-caffeoylquinic acid, luteoloside>3-O-caffeoylquinic acid>Secoxyloganin. Our results suggested that the phenolic compounds might significantly contribute to antibacterial activity and were the most responsible for the bacteriostatic activity of L. japonica leaves.
Cytotoxic activity of Guettarda pohliana Mull. Arg. (Rubiaceae).[Pubmed:23387288]
Nat Prod Res. 2013;27(18):1677-81.
The cytotoxic activity of crude extracts and their fractions from leaves and roots of G. pohliana was assessed against nine human cancer cell lines: melanoma (UACC-62), breast (MCF-7), breast expressing the multidrug resistance phenotype (NCI-ADR), lung (NCI-460), prostate (PCO-3), kidney (786-0), ovarian (OVCAR), colon (HT-29) and leukaemia (K-562). The hexane fraction from leaves (HL) and ethyl acetate (EAR), chloroform (CR) and hydromethanolic (HMR) fractions from roots were the most active fractions against K-562 with GI(5)(0) values being lower than 1 mug mL(-)(1). Also, CR and HMR fractions were active against UACC-62 cell line in the same order of magnitude. The phytochemical study of the CR fraction allowed identifying the known iridoids Secoxyloganin, sweroside and loganin.
[Chemical constituents from flower of Lonicera fragrantissima].[Pubmed:25726645]
Zhong Yao Cai. 2014 Aug;37(8):1383-5.
OBJECTIVE: To study the chemical constituents from the flower of Lonicera fragrantissima. METHODS: The chemical constituents were isolated and purified by means of several chromatographic techniques, and their structures were elucidated by spectroscopic methods. RESULTS: Nine compounds were isolated and identified as chlorogenic acid (1), caffeic acid (2), secologanoside (3), Secoxyloganin(4), loganin (5), sucrose (6), myo-inositol (7), rutin (8), and chrysoeriol-7-O-beta-D-glucoside (9). CONCLUSION: Compounds 2-9 are obtained from this plant for the first time.