Seneganolide

CAS# 301530-12-1

Seneganolide

Catalog No. BCN5209----Order now to get a substantial discount!

Product Name & Size Price Stock
Seneganolide: 5mg $1098 In Stock
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Quality Control of Seneganolide

Number of papers citing our products

Chemical structure

Seneganolide

3D structure

Chemical Properties of Seneganolide

Cas No. 301530-12-1 SDF Download SDF
PubChem ID 10695684 Appearance Powder
Formula C26H30O8 M.Wt 470.5
Type of Compound Triterpenoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (1S,2R,6R,7R,10R,11S,16S,19S,20S)-6-(furan-3-yl)-20-hydroxy-7,17,17-trimethyl-5,13,21-trioxahexacyclo[17.2.1.01,10.02,7.011,16.011,20]docosane-4,14,18-trione
SMILES CC1(C2CC(=O)OCC23C4CCC5(C(C46CC(C1=O)C3(O6)O)CC(=O)OC5C7=COC=C7)C)C
Standard InChIKey VIOKSDWKSSMHBF-MQELVVIJSA-N
Standard InChI InChI=1S/C26H30O8/c1-22(2)16-8-18(27)32-12-24(16)15-4-6-23(3)17(9-19(28)33-21(23)13-5-7-31-11-13)25(15)10-14(20(22)29)26(24,30)34-25/h5,7,11,14-17,21,30H,4,6,8-10,12H2,1-3H3/t14-,15+,16-,17+,21-,23+,24+,25+,26-/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Seneganolide

The heartwood of Khaya senegalensis

Biological Activity of Seneganolide

Description1. Seneganolide A has antifungal activity. 2. Seneganolide has insect antifeeding activity.
TargetsAntifection

Seneganolide Dilution Calculator

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Seneganolide Molarity Calculator

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Preparing Stock Solutions of Seneganolide

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.1254 mL 10.627 mL 21.254 mL 42.508 mL 53.135 mL
5 mM 0.4251 mL 2.1254 mL 4.2508 mL 8.5016 mL 10.627 mL
10 mM 0.2125 mL 1.0627 mL 2.1254 mL 4.2508 mL 5.3135 mL
50 mM 0.0425 mL 0.2125 mL 0.4251 mL 0.8502 mL 1.0627 mL
100 mM 0.0213 mL 0.1063 mL 0.2125 mL 0.4251 mL 0.5313 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Seneganolide

Antifungal limonoids from the fruits of Khaya senegalensis.[Pubmed:15351110]

Fitoterapia. 2004 Sep;75(6):566-72.

Investigation of the fruits of Khaya senegalensis resulted in the isolation of three new mexicanolide limonoids containing a rare conjugated diene lactone system named Seneganolide A (1), 2-hydroxySeneganolide A (2) and 2-acetoxySeneganolide A (3). Two known limonoids, 3-deacetyl-7-deacetoxy-7-oxokhivorin (4) and methyl 6-hydroxyangolensate (5), were also found. The structures of the new compounds were elucidated on the basis of spectral methods. The antifungal activity of compounds 1, 3 and 5 was tested against the fungus Botrytis cinerea.

Limonoids from the fruits of Khaya ivorensis.[Pubmed:24609020]

Molecules. 2014 Mar 7;19(3):3004-11.

Two new limonoids, namely 14,15-didehydroruageanin A (1) and 3-O-methyl- butyrylSeneganolide A (2), were isolated from the fruits of Khaya ivorensis along with six known limonoids: Seneganolide A (3), 1,3-dideacetylkhivorin (4), 7-deacetylkhivorin (5), 3-deacetylkhivorin (6), 1-deacetylkhivorin (7), and 3-deacetyl-7-oxokhivorin (8). All the compounds were evaluated for their cytotoxicity against five tumor cell lines.

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