SeneganolideCAS# 301530-12-1 |
Quality Control & MSDS
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| Cas No. | 301530-12-1 | SDF | Download SDF |
| PubChem ID | 10695684 | Appearance | Powder |
| Formula | C26H30O8 | M.Wt | 470.5 |
| Type of Compound | Triterpenoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | (1S,2R,6R,7R,10R,11S,16S,19S,20S)-6-(furan-3-yl)-20-hydroxy-7,17,17-trimethyl-5,13,21-trioxahexacyclo[17.2.1.01,10.02,7.011,16.011,20]docosane-4,14,18-trione | ||
| SMILES | CC1(C2CC(=O)OCC23C4CCC5(C(C46CC(C1=O)C3(O6)O)CC(=O)OC5C7=COC=C7)C)C | ||
| Standard InChIKey | VIOKSDWKSSMHBF-MQELVVIJSA-N | ||
| Standard InChI | InChI=1S/C26H30O8/c1-22(2)16-8-18(27)32-12-24(16)15-4-6-23(3)17(9-19(28)33-21(23)13-5-7-31-11-13)25(15)10-14(20(22)29)26(24,30)34-25/h5,7,11,14-17,21,30H,4,6,8-10,12H2,1-3H3/t14-,15+,16-,17+,21-,23+,24+,25+,26-/m0/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
The heartwood of Khaya senegalensis
| Description | 1. Seneganolide A has antifungal activity. 2. Seneganolide has insect antifeeding activity. |
| Targets | Antifection |
Seneganolide Dilution Calculator
Seneganolide Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.1254 mL | 10.627 mL | 21.254 mL | 42.508 mL | 53.135 mL |
| 5 mM | 0.4251 mL | 2.1254 mL | 4.2508 mL | 8.5016 mL | 10.627 mL |
| 10 mM | 0.2125 mL | 1.0627 mL | 2.1254 mL | 4.2508 mL | 5.3135 mL |
| 50 mM | 0.0425 mL | 0.2125 mL | 0.4251 mL | 0.8502 mL | 1.0627 mL |
| 100 mM | 0.0213 mL | 0.1063 mL | 0.2125 mL | 0.4251 mL | 0.5313 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Antifungal limonoids from the fruits of Khaya senegalensis.[Pubmed:15351110]
Fitoterapia. 2004 Sep;75(6):566-72.
Investigation of the fruits of Khaya senegalensis resulted in the isolation of three new mexicanolide limonoids containing a rare conjugated diene lactone system named Seneganolide A (1), 2-hydroxySeneganolide A (2) and 2-acetoxySeneganolide A (3). Two known limonoids, 3-deacetyl-7-deacetoxy-7-oxokhivorin (4) and methyl 6-hydroxyangolensate (5), were also found. The structures of the new compounds were elucidated on the basis of spectral methods. The antifungal activity of compounds 1, 3 and 5 was tested against the fungus Botrytis cinerea.
Limonoids from the fruits of Khaya ivorensis.[Pubmed:24609020]
Molecules. 2014 Mar 7;19(3):3004-11.
Two new limonoids, namely 14,15-didehydroruageanin A (1) and 3-O-methyl- butyrylSeneganolide A (2), were isolated from the fruits of Khaya ivorensis along with six known limonoids: Seneganolide A (3), 1,3-dideacetylkhivorin (4), 7-deacetylkhivorin (5), 3-deacetylkhivorin (6), 1-deacetylkhivorin (7), and 3-deacetyl-7-oxokhivorin (8). All the compounds were evaluated for their cytotoxicity against five tumor cell lines.
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