Serrin ACAS# 845959-98-0 |
Quality Control & MSDS
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| Cas No. | 845959-98-0 | SDF | Download SDF |
| PubChem ID | 11269305 | Appearance | Powder |
| Formula | C22H30O6 | M.Wt | 390.47 |
| Type of Compound | Diterpenoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | (1S,4S,8R,9R,12R,13S,16R)-9-ethoxy-11-hydroxy-7,7-dimethyl-17-methylidene-3,10-dioxapentacyclo[14.2.1.01,13.04,12.08,12]nonadecane-2,18-dione | ||
| SMILES | CCOC1C2C(CCC3C2(C4CCC5CC4(C(=O)C5=C)C(=O)O3)C(O1)O)(C)C | ||
| Standard InChIKey | BYOLCBRZEMRXHS-BGPRIOEDSA-N | ||
| Standard InChI | InChI=1S/C22H30O6/c1-5-26-17-15-20(3,4)9-8-14-22(15,19(25)28-17)13-7-6-12-10-21(13,18(24)27-14)16(23)11(12)2/h12-15,17,19,25H,2,5-10H2,1,3-4H3/t12-,13-,14+,15-,17-,19?,21+,22+/m1/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
The herbs of Rabdosia serra.
| Description | 1. Serrin A shows weak to moderate cytotoxic activities (IC50<10 uM) against two human cancer cell lines. |
Serrin A Dilution Calculator
Serrin A Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.561 mL | 12.8051 mL | 25.6102 mL | 51.2203 mL | 64.0254 mL |
| 5 mM | 0.5122 mL | 2.561 mL | 5.122 mL | 10.2441 mL | 12.8051 mL |
| 10 mM | 0.2561 mL | 1.2805 mL | 2.561 mL | 5.122 mL | 6.4025 mL |
| 50 mM | 0.0512 mL | 0.2561 mL | 0.5122 mL | 1.0244 mL | 1.2805 mL |
| 100 mM | 0.0256 mL | 0.1281 mL | 0.2561 mL | 0.5122 mL | 0.6403 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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ent-6,7-Secokaurane diterpenoids from Rabdosia serra and their cytotoxic activities.[Pubmed:26671519]
Phytochemistry. 2016 Feb;122:119-125.
Investigation of the hydrophobic extract of Rabdosia serra (Lamiaceae) led to the isolation of seven ent-6,7-secokaurane diterpenoids rabdosins E-K, along with twelve known ent-kaurane diterpenoids. Their structures were established by extensive spectroscopic analysis. The absolute configurations of rabdosins E, F, H and I were determined by single-crystal X-ray diffraction, with rabdosin E having a 3,20-epoxy group. These diterpenoids could be divided into two types according to their skeletons: rabdosins E-J are ent-6,20-epoxy-6,7-secokaur-1,7-olides, and rabdosin K is an ent-6,7-secokaur-7,20-olide. Cytotoxicity evaluation showed that serrin B, Serrin A, isodocarpin and lushanrubescensin J exhibited weak to moderate cytotoxic activities (IC50<10muM) against two human cancer cell lines.
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