Tasumatrol L

CAS# 847835-17-0

Tasumatrol L

Catalog No. BCN6955----Order now to get a substantial discount!

Product Name & Size Price Stock
Tasumatrol L: 5mg $1012 In Stock
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Quality Control of Tasumatrol L

Number of papers citing our products

Chemical structure

Tasumatrol L

3D structure

Chemical Properties of Tasumatrol L

Cas No. 847835-17-0 SDF Download SDF
PubChem ID 11158380 Appearance Powder
Formula C36H44O15 M.Wt 716.73
Type of Compound Diterpenoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
SMILES CC(=O)OC1CC(C(=C)C2C1(C(C(C3(C4(COC3(C(=O)C(C4C2OC(=O)C)CO)C)C)O)OC(=O)C)OC(=O)C)COC(=O)C5=CC=CC=C5)O
Standard InChIKey ZFXSJZPTCKIFHG-CXFIUYFASA-N
Standard InChI InChI=1S/C36H44O15/c1-17-24(42)13-25(48-18(2)38)35(16-46-32(44)22-11-9-8-10-12-22)26(17)28(49-19(3)39)27-23(14-37)29(43)34(7)36(45,33(27,6)15-47-34)31(51-21(5)41)30(35)50-20(4)40/h8-12,23-28,30-31,37,42,45H,1,13-16H2,2-7H3/t23-,24+,25+,26+,27+,28+,30+,31+,33+,34-,35-,36+/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Tasumatrol L

The leaves and twigs of Taxus sumatrana.

Biological Activity of Tasumatrol L

DescriptionTasumatrol L is a natural product from Taxus sumatrana.

Protocol of Tasumatrol L

Structure Identification
Tetrahedron, 2005, 61(5):1345-1352.

Novel taxane diterpenes from Taxus sumatrana with the first C-21 taxane ester.[Reference: WebLink]


METHODS AND RESULTS:
Phytochemical investigation of the taxane diterpenes content of an acetone extract of the leaves and twigs of Taxus sumatrana (Taxaceae) has resulted in the isolation of five new taxane diterpenes esters, tasumatrol H, tasumatrol I, tasumatrol J, tasumatrol K, Tasumatrol L (1–5) together with 13 known taxanes (11–23). Compound 5 is the first 21-carbon taxane ester to be isolated from a natural source. The structures of these taxanes as well as their derivatives were established on the basis of spectral analyses, especially MS as well as 1-and 2D NMR.
CONCLUSIONS:
Compounds 2 and 4 showed significant activity against human liver carcinoma (Hepa59T/VGH), human large cell carcinoma of the lungs (NCI), human cervical epitheloid carcinoma (Hela), human colon adenocarcinoma (DLD-1) and human medulloblastoma (Med) cell lines.

Tasumatrol L Dilution Calculator

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Tasumatrol L Molarity Calculator

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Preparing Stock Solutions of Tasumatrol L

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.3952 mL 6.9761 mL 13.9523 mL 27.9045 mL 34.8806 mL
5 mM 0.279 mL 1.3952 mL 2.7905 mL 5.5809 mL 6.9761 mL
10 mM 0.1395 mL 0.6976 mL 1.3952 mL 2.7905 mL 3.4881 mL
50 mM 0.0279 mL 0.1395 mL 0.279 mL 0.5581 mL 0.6976 mL
100 mM 0.014 mL 0.0698 mL 0.1395 mL 0.279 mL 0.3488 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Tasumatrol L

Novel taxane diterpenes from Taxus sumatrana with the first C-21 taxane ester.

Tetrahedron, 2005, 61(5):1345-1352.

Phytochemical investigation of the taxane diterpenes content of an acetone extract of the leaves and twigs of Taxus sumatrana (Taxaceae) has resulted in the isolation of five new taxane diterpenes esters, tasumatrol H, tasumatrol I, tasumatrol J, tasumatrol K, Tasumatrol L (1–5) together with 13 known taxanes (11–23). Compound 5 is the first 21-carbon taxane ester to be isolated from a natural source. The structures of these taxanes as well as their derivatives were established on the basis of spectral analyses, especially MS as well as 1-and 2D NMR. Compounds 2 and 4 showed significant activity against human liver carcinoma (Hepa59T/VGH), human large cell carcinoma of the lungs (NCI), human cervical epitheloid carcinoma (Hela), human colon adenocarcinoma (DLD-1) and human medulloblastoma (Med) cell lines.

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