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Tiamulin

CAS# 55297-95-5

Tiamulin

2D Structure

Catalog No. BCC9179----Order now to get a substantial discount!

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Tiamulin: 5mg $17 In Stock
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Quality Control of Tiamulin

3D structure

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Tiamulin

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Chemical Properties of Tiamulin

Cas No. 55297-95-5 SDF Download SDF
PubChem ID 656958 Appearance Powder
Formula C28H47NO4S M.Wt 493.7
Type of Compound N/A Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
SMILES CCN(CC)CCSCC(=O)OC1CC(C(C(C23CCC(C1(C2C(=O)CC3)C)C)C)O)(C)C=C
Standard InChIKey UURAUHCOJAIIRQ-QGLSALSOSA-N
Standard InChI InChI=1S/C28H47NO4S/c1-8-26(6)17-22(33-23(31)18-34-16-15-29(9-2)10-3)27(7)19(4)11-13-28(20(5)25(26)32)14-12-21(30)24(27)28/h8,19-20,22,24-25,32H,1,9-18H2,2-7H3/t19-,20+,22-,24+,25+,26-,27+,28+/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Tiamulin Dilution Calculator

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Tiamulin Molarity Calculator

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Preparing Stock Solutions of Tiamulin

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.0255 mL 10.1276 mL 20.2552 mL 40.5104 mL 50.638 mL
5 mM 0.4051 mL 2.0255 mL 4.051 mL 8.1021 mL 10.1276 mL
10 mM 0.2026 mL 1.0128 mL 2.0255 mL 4.051 mL 5.0638 mL
50 mM 0.0405 mL 0.2026 mL 0.4051 mL 0.8102 mL 1.0128 mL
100 mM 0.0203 mL 0.1013 mL 0.2026 mL 0.4051 mL 0.5064 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Tiamulin

Antimicrobial Susceptibility Profile of Enterococcus Species Isolated from Companion Birds and Poultry in the Northeast of Iran.[Pubmed:30280840]

Arch Razi Inst. 2018 Sep;73(3):207-213.

Enterococci are Gram-positive facultative anaerobic bacteria commonly found in the gastrointestinal tract of the mammals and birds. These cocci are isolated from urinary tract infections, bacteremia, endocarditis, and burn wounds in humans. The evolution of antibiotic-resistant enterococci raised a problem due to the possibility of the transmission of these organisms between poultry and human. Regarding this, the present study was conducted to evaluate the prevalence of Enterococcus species among companion birds and poultry in the Northeastern of Iran and determine the antibiotic susceptibility profile of enterococci. To this end, oral and cloacal swabs were collected from 150 caged birds. Antibiotic susceptibility profile was determined using the standard disk diffusion method. The results revealed that out of 150 samples, 56 (37.33%) cases contained enterococci. Most of the specimens (25.33%) were Enterococcus faecalis isolated from 6.66% of the samples. Additionally, 2.66% and 1.33% of the samples were contaminated with Enterococcus mundtii and Enterococcus gallinarum, respectively. Furthermore, Enterococcus malodoratus and Enterococcus raffinosus were isolated from 0.66% of the samples. The results revealed that all of the isolates of E. faecalis and E. faecium were resistant to more than five antimicrobial agents. Most of E. faecalis and E. faecium isolates showed resistance to Cefazolin, Tiamulin, Flumequine, and Cephalexin. Accordingly, the majority of the isolates had multidrug resistance to the tested antibiotics. In conclusion, the presence of multidrug-resistant enterococci in the birds living close to humans requires thorough observations due to the transmission of these organisms to humans.

Description

Tiamulin (Thiamutilin) is a diterpenic veterinary drug widely used in swine for the control of infectious diseases, including swine dysentery and enzootic pneumonia.

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