Wilforol ACAS# 167882-66-8 |
Quality Control & MSDS
3D structure
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Number of papers citing our products
| Cas No. | 167882-66-8 | SDF | Download SDF |
| PubChem ID | 10096097 | Appearance | Powder |
| Formula | C29H38O5 | M.Wt | 466.6 |
| Type of Compound | Triterpenoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | (2R,4aS,6aR,6aS,14aS,14bR)-10,11-dihydroxy-2,4a,6a,6a,9,14a-hexamethyl-8-oxo-1,3,4,5,6,13,14,14b-octahydropicene-2-carboxylic acid | ||
| SMILES | CC1=C2C(=CC(=C1O)O)C3(CCC4(C5CC(CCC5(CCC4(C3=CC2=O)C)C)(C)C(=O)O)C)C | ||
| Standard InChIKey | MIQDJLKXHZPMHH-CPISFEQASA-N | ||
| Standard InChI | InChI=1S/C29H38O5/c1-16-22-17(13-19(31)23(16)32)27(4)10-12-29(6)21-15-26(3,24(33)34)8-7-25(21,2)9-11-28(29,5)20(27)14-18(22)30/h13-14,21,31-32H,7-12,15H2,1-6H3,(H,33,34)/t21-,25-,26-,27+,28-,29+/m1/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | Wilforol A is a natural product from Tripterygium wilfordii Hook. f. |
| Structure Identification | J Am Chem Soc. 2015 Sep 23;137(37):11864-7.Total Synthesis of Celastrol, Development of a Platform to Access Celastroid Natural Products.[Pubmed: 26331410 ]Celastroid natural products, triterpenes, have been and continue to be investigated in clinical trials.
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Wilforol A Dilution Calculator
Wilforol A Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.1432 mL | 10.7158 mL | 21.4316 mL | 42.8633 mL | 53.5791 mL |
| 5 mM | 0.4286 mL | 2.1432 mL | 4.2863 mL | 8.5727 mL | 10.7158 mL |
| 10 mM | 0.2143 mL | 1.0716 mL | 2.1432 mL | 4.2863 mL | 5.3579 mL |
| 50 mM | 0.0429 mL | 0.2143 mL | 0.4286 mL | 0.8573 mL | 1.0716 mL |
| 100 mM | 0.0214 mL | 0.1072 mL | 0.2143 mL | 0.4286 mL | 0.5358 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Total Synthesis of Celastrol, Development of a Platform to Access Celastroid Natural Products.[Pubmed:26331410]
J Am Chem Soc. 2015 Sep 23;137(37):11864-7.
Celastroid natural products, triterpenes, have been and continue to be investigated in clinical trials. Celastrol, and for that matter any member of the celastroid family, was prepared for the first time through chemical synthesis starting from 2,3-dimethylbutadiene. A triene cyclization precursor generated in 12 steps underwent a nonbiomimetic polyene cyclization mediated by ferric chloride to generate the generic celastroid pentacyclic core. In the cyclization, engagement of a tetrasubstituted olefin formed adjacent all carbon quaternary centers stereospecifically. With access to the carbocyclic core of the family of natural products, wilforic acid and Wilforol A were prepared en route to racemic celastrol.
