PD-1/PD-L1 inhibitor 2PD-1/PD-L1 interaction inhibitor CAS# 1675203-84-5 |
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Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
Cas No. | 1675203-84-5 | SDF | Download SDF |
PubChem ID | 117951478 | Appearance | Powder |
Formula | C25H29N3O3 | M.Wt | 419.52 |
Type of Compound | N/A | Storage | Desiccate at -20°C |
Synonyms | PD-1/PD-L1 inhibitor 2 | ||
Solubility | DMSO : ≥ 100 mg/mL (238.37 mM) *"≥" means soluble, but saturation unknown. | ||
Chemical Name | N-[2-[[2-methoxy-6-[(2-methyl-3-phenylphenyl)methoxy]pyridin-3-yl]methylamino]ethyl]acetamide | ||
SMILES | CC1=C(C=CC=C1COC2=NC(=C(C=C2)CNCCNC(=O)C)OC)C3=CC=CC=C3 | ||
Standard InChIKey | JEDPSOYOYVELLZ-UHFFFAOYSA-N | ||
Standard InChI | InChI=1S/C25H29N3O3/c1-18-22(10-7-11-23(18)20-8-5-4-6-9-20)17-31-24-13-12-21(25(28-24)30-3)16-26-14-15-27-19(2)29/h4-13,26H,14-17H2,1-3H3,(H,27,29) | ||
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. |
Description | BMS-202 is an inhibitor of the PD-1/PD-L1 protein/protein interaction, mainly used for cancer treatment.In Vitro:BMS-202 inhibits PD-1/PD-Ll interaction, and may augment therapeutic immune response to a number of histologically distinct tumors. Blockade of the PD-1/PD-Ll ligation using antibodies to PD-Ll has been shown to restore and augment T cell activation in many systems[1]. References: |
PD-1/PD-L1 inhibitor 2 Dilution Calculator
PD-1/PD-L1 inhibitor 2 Molarity Calculator
1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
1 mM | 2.3837 mL | 11.9184 mL | 23.8368 mL | 47.6735 mL | 59.5919 mL |
5 mM | 0.4767 mL | 2.3837 mL | 4.7674 mL | 9.5347 mL | 11.9184 mL |
10 mM | 0.2384 mL | 1.1918 mL | 2.3837 mL | 4.7674 mL | 5.9592 mL |
50 mM | 0.0477 mL | 0.2384 mL | 0.4767 mL | 0.9535 mL | 1.1918 mL |
100 mM | 0.0238 mL | 0.1192 mL | 0.2384 mL | 0.4767 mL | 0.5959 mL |
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. |
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PD-1/PD-L1 inhibitor 2 is a PD-1/PD-L1 interaction inhibitor.
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