Calmodulin-Dependent Kinase

Calmodulin-dependent kinases (CaMK) are a family of serine/threonine kinases that mediate many of the second messenger effects of Ca2+. At basal Ca2+ levels, CaMKs are maintained in a dormant state through autoinhibition, which can be relieved by increases in Ca2+ levels.

Products for Calmodulin-Dependent Kinase

  1. Cat.No. Product Name Information/Activity
  2. BCC6203 A 484954 A-484954 is a highly selective eukaryotic elongationfactor-2 (eEF2) inhibitor, with an IC50 of 280 nM. A 484954 chemical structure
  3. BCC7370 Arcyriaflavin A Potent cdk4/cyclin D1 and CaM Kinase II inhibitor. Antiviral agent (anti-HCMV) Arcyriaflavin A chemical structure
  4. BCC7153 Autocamtide-2-related inhibitory peptide Selective CaM kinase II inhibitor Autocamtide-2-related inhibitory peptide chemical structure
  5. BCC5638 KN-93 Phosphate KN-93 Phosphate is a potent and specific inhibitor of Ca2+/calmodulin-dependent protein kinase II (CaMKII) with Ki of 0.37 μM, no remarkable inhibitory effects on APK, PKC, MLCK or Ca2+-PDE activities. KN-93 Phosphate chemical structure
  6. BCC3602 KN-62 KN-62 is a selective and potent inhibitor of calmodulin-dependent protein kinase II (CaMK-II) with IC50 of 0.9 μM, KN-62 also displays noncompetitive antagonism at P2X7 receptors in HEK293 cells, with an IC50 value of approximately 15 nM. KN-62 chemical structure
  7. BCC1683 KN-93 CaM kinase II inhibitor; also K<sup>+</sup> channel blocker (K<sub>V</sub>),KN-93 is a novel membrane-permeant synthetic inhibitor of purified neuronal <b>CaMK-II</b>, with K<sub>i</sub> of 370 nM. KN-93 chemical structure
  8. BCC4001 NH125 NH125 is a potent and selective inhibitor of eukaryotic elongation factor 2 kinase (eEF-2K/CaMKIII), also can induce eEF2 phosphorylation, with an IC50 of 60 nM for eEF-2K. NH125 chemical structure
  9. BCC7112 STO-609 acetate 1173022-21-3 STO-609 acetate chemical structure

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