Atherosclerosis Research

Atherosclerosis is a disease of the arterial system that is characterized by the accumulation of fatty deposits within arterial walls, known as 'atherosclerotic plaques'.

Atherosclerosis Research Products Targets

Products for Atherosclerosis Research - Page 7

Cat.No. Product Name Information/Activity
BCC6365 iMDK 881970-80-5
BCC6023 4-IPP 4-IPP (4-Iodo-6-phenylpyrimidine) is a specific suicide substrate and irreversible inhibitor of macrophage migration inhibitory factor (MIF).
BCC5427 ISO-1 ISO-1 is a macrophage migration inhibitory factor (MIF) antagonist with an IC50 of 7 μM.
BCC7960 (D)-(+)-Neopterin D-(+)-Neopterin, a catabolic product of guanosine triphosphate (GTM), serves as a marker of cellular immune system activation.
BCC5086 Pirfenidone Pirfenidone (AMR69) is an antifibrotic agent that attenuates CCL2 and CCL12 production in fibrocyte cells. Pirfenidone has growth-inhibitory effect and reduces TGF-β2 protein levels in human glioma cell lines. Pirfenidone also has anti-inflammatory activities.
BCC7236 SKF 86002 dihydrochloride 116339-68-5
BCC4961 Suplatast Tosylate Suplatast Tosilate (IPD 1151T) is a Th2 cytokine inhibitor that attenuates IL-2, IL-5 and IL-13 production and has no effect on IFN-γ production.
BCC2248 Thalidomide Thalidomide is initially promoted as a sedative, inhibits cereblon (CRBN), a part of the cullin-4 E3 ubiquitin ligase complex CUL4-RBX1-DDB1, with a Kd of ∼250 nM, and has immunomodulatory, anti-inflammatory and anti-angiogenic cancer properties.
BCC5812 AF 12198 Potent, selective human type I IL-1 receptor antagonist
BCC7149 YM 90709 YM-90709 is a novel antagonist which inhibits the binding of interleukin-5 to interleukin-5 receptor.