Stem Cell Differentiation
Stem cell differentiation involves the changing of a cell to a more specialized cell type, involving a switch from proliferation to specialization. This involves a succession of alterations in cell morphometry, membrane potential, metabolic activity and signal responsiveness.
Products for Stem Cell Differentiation - Page 2
- Cat.No. Product Name Information/Activity
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BCC8079
Dibutyryl-cAMP, sodium salt
Bucladesine sodium salt (Dibutyryl-cAMP sodium salt) is a stabilized cyclic AMP (cAMP) analog and a selective PKA activator. Bucladesine sodium salt raises the intracellular levels of cAMP. Bucladesine sodium salt is also a phosphodiesterase (PDE) inhibitor. Bucladesine sodium salt has anti-inflammatory activity and can be used for impaired wound healing.
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BCC5329
DMH-1
DMH-1 is a potent and selective BMP inhibitor with IC50s of 27/107.9/<5/47.6 nM for ALK1/ALK2/ALK3/ALK6, respectively.
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BCC4361
Dorsomorphin 2HCl
Dorsomorphin dihydrochloride (Compound C dihydrochloride) is a potent, selective and ATP-competitive AMPK inhibitor, with a Ki of 109 nM. Dorsomorphin dihydrochloride inhibits BMP pathway by targeting the type I receptors ALK2, ALK3, and ALK6. Dorsomorphin dihydrochloride induces autophagy.
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BCC6904
1-EBIO
10045-45-1
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BCC6097
EC 23
EC23 (AGN 190205) is a stable synthetic retinoid analogue and induces neuronal differentiation.
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BCC5341
FH1(BRD-K4477)
FH1(BRDK4477) is a small molecule that can enhance the functions of cultured hepatocytes.
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BCC1191
Fluoxetine HCl
Fluoxetine hydrochloride (LY 110140) is an antidepressant and a selective serotonin reuptake inhibitor.
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BCN2332
Forskolin
Forskolin (Coleonol) is a potent adenylate cyclase activator with an IC50 of 41 nM and an EC50 of 0.5 μM for type I adenylyl cyclase. Forskolin is also an inducer of intracellular cAMP formation. Forskolin induces differentiation of various cell types and activates pregnane X receptor (PXR) and FXR. Forskolin exerts a inotropic effect on the heart, and has platelet antiaggregatory and antihypertensive actions. Forskolin also induces autophagy.
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BCC6329
GSA 10
300833-95-8
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BCC7502
IBMX
IBMX is a broad-spectrum phosphodiesterase (PDE) inhibitor, with IC50s of 6.5, 26.3 and 31.7 μM for PDE3, PDE4 and PDE5, respectively.
