Immunology Research

Immunology is a branch of science that studies all aspects of the immune system, ranging from normal physiological functioning through to malfunctions which can lead to immunological diseases. Disorders that result from aberrant activation of the immune system are termed autoimmune diseases.

Immunology Research Products Areas

Products for Immunology Research - Page 52

Cat.No. Product Name Information/Activity
BCC5267 4-Aminopyridine 4-Aminopyridine is a nonselective K+ channel blocker that binds from the cytoplasmic side of the cell membrane.
BCC7691 Astemizole Astemizole (R 43512), a second-generation antihistamine drug to diminish allergic symptoms with a long duration of action, is a histamine H1-receptor antagonist, with an IC50 of 4 nM. Astemizole also shows potent hERG K+ channel blocking activity with an IC50 of 0.9 nM. Astemizole has antipruritic effects.
BCC5456 BAPTA-AM BAPTA-AM is a well-known membrane permeable Ca2+ chelator. BAPTA-AM inhibits hERG channels, hKv1.3 and hKv1.5 channels in HEK 293 cells with IC50s of 1.3 μM, 1.45 μM and 1.23 μM, respectively.
BCC7055 Chromanol 293B 163163-23-3
BCC7080 (-)-[3R,4S]-Chromanol 293B 163163-24-4
BCC7048 CP 339818 hydrochloride 478341-55-8
BCC3770 Dofetilide Dofetilide(Tikosyn) is a class III antiarrhythmic agent.
BCC7398 DPO-1 43077-30-1
BCC7182 E-4031 dihydrochloride E-4031 is a class III antiarrhythmic agent which selectively blocks hERG potassium channel.
BCC7806 JNJ 303 JNJ 303 is a potent IKs blocker with an IC50 value of 64 nM. JNJ 303 does not have any effects on other cardiac channels at concentrations of 3.3 μM for INa, Ica, Ito, and IKr. JNJ 303 induces QT-prolongations and causes unprovoked torsades de pointes (TdP).