Voltage-gated Potassium (KV) Channels
Voltage-gated potassium channels (KV) belong to the 6-TM family of potassium channel that also comprises the Ca2+-activated Slo (actually 7-TM) and the Ca2+-activated SK subfamilies. The α -subunits contain a single pore-forming region and combine to form tetramers.
Products for Voltage-gated Potassium (KV) Channels - Page 3
- Cat.No. Product Name Information/Activity
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BCC3770
Dofetilide
Dofetilide(Tikosyn) is a class III antiarrhythmic agent.
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BCC7398
DPO-1
43077-30-1
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BCC7182
E-4031 dihydrochloride
E-4031 is a class III antiarrhythmic agent which selectively blocks hERG potassium channel.
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BCC7806
JNJ 303
JNJ 303 is a potent IKs blocker with an IC50 value of 64 nM. JNJ 303 does not have any effects on other cardiac channels at concentrations of 3.3 μM for INa, Ica, Ito, and IKr. JNJ 303 induces QT-prolongations and causes unprovoked torsades de pointes (TdP).
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BCC7710
Kaliotoxin
145199-73-1
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BCC1682
KN-92 phosphate
KN-92 phosphate is an inactive derivative of KN-93.
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BCC1683
KN-93
CaM kinase II inhibitor; also K<sup>+</sup> channel blocker (K<sub>V</sub>),KN-93 is a novel membrane-permeant synthetic inhibitor of purified neuronal <b>CaMK-II</b>, with K<sub>i</sub> of 370 nM.
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BCC7231
Linopirdine dihydrochloride
113168-57-3
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BCC7709
Margatoxin
Margatoxin, an alpha-KTx scorpion toxin, is a high affinity inhibitor of Kv1.3 (Kd=11.7 pM). Margatoxin inhibits the Kv1.2 (Kd=6.4 pM) and Kv1.1 (Kd=4.2 nM). Margatoxin, a 39 amino-acid-long peptide, is isolated from the venom of the scorpion Centruroides margaritatus and widely used in ion channel research.
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BCC6255
ProTx I
484598-35-8
