Parkinson's Disease Research

Parkinson's disease (PD) is a degenerative disease of the central nervous system that often impairs motor skills, speech, and other functions. Symptoms of the disease include resting tremor, bradykinesia and rigidity. The primary symptoms are the result of decreased stimulation of the motor cortex by the basal ganglia, normally caused by the insufficient formation and action of dopamine, which is produced in the dopaminergic neurons of the brain. Symptoms of the disease appear once 50-80% of dopamine neurons have died. Parkinson's disease is both chronic and progressive.

Parkinson's Disease Research Products Targets

Products for Parkinson's Disease Research - Page 6

  1. Cat.No. Product Name Information/Activity
  2. BCN2187 4-Aminobutanoic acid γ-Aminobutyric acid (4-Aminobutyric acid) is a major inhibitory neurotransmitter in the adult mammalian brain, binding to the ionotropic GABA receptors (GABAA receptors) and metabotropic receptors (GABAB receptors). 4-Aminobutanoic acid chemical structure
  3. BCC6012 RuBi-GABA 1028141-88-9 RuBi-GABA chemical structure
  4. BCC6626 SKF 97541 127729-35-5 SKF 97541 chemical structure
  5. BCC6988 CGP 35348 Brain penetrant, selective GABA<sub>B</sub> antagonist CGP 35348 chemical structure
  6. BCC7605 CGP 36216 hydrochloride GABA<sub>B</sub> antagonist; displays activity at presynaptic receptors CGP 36216 hydrochloride chemical structure
  7. BCC6990 CGP 46381 123691-14-5 CGP 46381 chemical structure
  8. BCC6989 CGP 52432 CGP52432 is a GABAB receptor antagonist, with an IC50 of 85 nM. CGP 52432 chemical structure
  9. BCC6934 CGP 54626 hydrochloride 149184-21-4 CGP 54626 hydrochloride chemical structure
  10. BCC5737 CGP 55845 hydrochloride Potent, selective GABA<sub>B</sub> antagonist CGP 55845 hydrochloride chemical structure
  11. BCC6579 2-Hydroxysaclofen 117354-64-0 2-Hydroxysaclofen chemical structure

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